ko	pathway	ratio_in_study	ratio_in_pop	p_value
ko04380	Osteoclast differentiation	43/495	134/7206	1.21881731451e-18
ko04060	Cytokine-cytokine receptor interaction	49/495	191/7206	1.40608951728e-16
ko04621	NOD-like receptor signaling pathway	40/495	157/7206	1.29403915611e-13
ko04064	NF-kappa B signaling pathway	30/495	96/7206	5.26069889228e-13
ko05164	Influenza A	40/495	167/7206	1.14512995468e-12
ko05140	Leishmaniasis	26/495	75/7206	1.28922950836e-12
ko04668	TNF signaling pathway	32/495	120/7206	1.0619347619e-11
ko05162	Measles	30/495	120/7206	2.73029476442e-10
ko05321	Inflammatory bowel disease (IBD)	20/495	56/7206	2.88367086185e-10
ko04610	Complement and coagulation cascades	23/495	79/7206	1.39326281742e-09
ko05152	Tuberculosis	37/495	187/7206	2.8701218263e-09
ko05323	Rheumatoid arthritis	24/495	89/7206	3.37825702885e-09
ko05150	Staphylococcus aureus infection	15/495	36/7206	4.20889194294e-09
ko05168	Herpes simplex infection	36/495	182/7206	4.77813893252e-09
ko04659	Th17 cell differentiation	26/495	106/7206	6.73440457053e-09
ko04217	Necroptosis	35/495	178/7206	9.27173053418e-09
ko04630	Jak-STAT signaling pathway	29/495	132/7206	1.35243210036e-08
ko04620	Toll-like receptor signaling pathway	24/495	100/7206	4.08511001468e-08
ko05133	Pertussis	22/495	87/7206	5.5138517093e-08
ko05145	Toxoplasmosis	27/495	126/7206	7.52024364695e-08
ko04933	AGE-RAGE signaling pathway in diabetic complications	28/495	135/7206	8.99758379198e-08
ko04650	Natural killer cell mediated cytotoxicity	23/495	97/7206	9.99206609935e-08
ko05161	Hepatitis B	32/495	173/7206	1.82285796079e-07
ko04660	T cell receptor signaling pathway	26/495	124/7206	2.08244889957e-07
ko04658	Th1 and Th2 cell differentiation	22/495	96/7206	3.60547609952e-07
ko04672	Intestinal immune network for IgA production	13/495	37/7206	5.00632821674e-07
ko05144	Malaria	14/495	45/7206	9.97392854483e-07
ko04662	B cell receptor signaling pathway	20/495	88/7206	1.41629747961e-06
ko05340	Primary immunodeficiency	11/495	30/7206	2.36976063308e-06
ko05167	Kaposi's sarcoma-associated herpesvirus infection	32/495	191/7206	2.85534820526e-06
ko04210	Apoptosis	30/495	180/7206	6.60417218099e-06
ko04623	Cytosolic DNA-sensing pathway	12/495	41/7206	1.21281876229e-05
ko05142	Chagas disease (American trypanosomiasis)	23/495	130/7206	2.12646957834e-05
ko00120	Primary bile acid biosynthesis	8/495	20/7206	2.82229191151e-05
ko05132	Salmonella infection	19/495	98/7206	2.97775316648e-05
ko05160	Hepatitis C	25/495	153/7206	5.48969142911e-05
ko04622	RIG-I-like receptor signaling pathway	14/495	62/7206	5.86670220455e-05
ko04657	IL-17 signaling pathway	17/495	87/7206	7.01069681101e-05
ko05310	Asthma	7/495	17/7206	7.33803727232e-05
ko04640	Hematopoietic cell lineage	14/495	64/7206	8.49995806023e-05
ko03013	RNA transport	1/495	166/7206	0.000143849372173
ko04612	Antigen processing and presentation	15/495	77/7206	0.000192382742954
ko04670	Leukocyte transendothelial migration	23/495	151/7206	0.000250689621039
ko04062	Chemokine signaling pathway	28/495	201/7206	0.000306391487523
ko05418	Fluid shear stress and atherosclerosis	25/495	173/7206	0.000345317476791
ko04611	Platelet activation	24/495	163/7206	0.00039455995144
ko05320	Autoimmune thyroid disease	8/495	29/7206	0.000554065581446
ko05330	Allograft rejection	7/495	24/7206	0.000855845325292
ko05332	Graft-versus-host disease	6/495	18/7206	0.000927722581308
ko05134	Legionellosis	13/495	74/7206	0.00140573039177
ko05034	Alcoholism	5/495	238/7206	0.00151992555308
ko04666	Fc gamma R-mediated phagocytosis	18/495	122/7206	0.00173215963506
ko05166	HTLV-I infection	34/495	292/7206	0.00201023269997
ko01200	Carbon metabolism	1/495	128/7206	0.00217560943189
ko05131	Shigellosis	13/495	82/7206	0.00362389559242
ko04916	Melanogenesis	2/495	142/7206	0.00410518609104
ko04145	Phagosome	21/495	162/7206	0.00420296801695
ko04940	Type I diabetes mellitus	7/495	32/7206	0.00515616219256
ko04713	Circadian entrainment	2/495	136/7206	0.00585790887406
ko04664	Fc epsilon RI signaling pathway	12/495	77/7206	0.00586988664815
ko04972	Pancreatic secretion	1/495	111/7206	0.00681943017276
ko05012	Parkinson's disease	3/495	155/7206	0.00937226527291
ko04068	FoxO signaling pathway	20/495	167/7206	0.0127272281754
ko05016	Huntington's disease	6/495	215/7206	0.013008774677
ko05212	Pancreatic cancer	12/495	83/7206	0.0132815241594
ko04724	Glutamatergic synapse	3/495	152/7206	0.0135355202828
ko04144	Endocytosis	35/495	342/7206	0.0156159189028
ko04931	Insulin resistance	17/495	137/7206	0.0156953308957
ko04932	Non-alcoholic fatty liver disease (NAFLD)	21/495	182/7206	0.0168613940682
ko05020	Prion diseases	7/495	40/7206	0.017778042387
ko04728	Dopaminergic synapse	5/495	185/7206	0.0179962646437
ko05143	African trypanosomiasis	6/495	32/7206	0.0199735637308
ko00140	Steroid hormone biosynthesis	7/495	41/7206	0.020212084473
ko00051	Fructose and mannose metabolism	7/495	42/7206	0.0228691916776
ko00350	Tyrosine metabolism	6/495	33/7206	0.0230418761332
ko05169	Epstein-Barr virus infection	23/495	206/7206	0.023865688099
ko00590	Arachidonic acid metabolism	8/495	52/7206	0.0242608095062
ko05146	Amoebiasis	13/495	99/7206	0.0243537918584
ko04114	Oocyte meiosis	3/495	139/7206	0.0256116478143
ko00643	Styrene degradation	2/495	4/7206	0.0257464403795
ko04010	MAPK signaling pathway	32/495	321/7206	0.0312432227341
ko05120	Epithelial cell signaling in Helicobacter pylori infection	12/495	92/7206	0.0336979326535
ko04727	GABAergic synapse	2/495	110/7206	0.0339582201652
ko05032	Morphine addiction	2/495	110/7206	0.0339582201652
ko04540	Gap junction	3/495	128/7206	0.0343559084279
ko04390	Hippo signaling pathway	6/495	188/7206	0.0403231172185
ko00400	Phenylalanine, tyrosine and tryptophan biosynthesis	2/495	5/7206	0.0409761355624
ko04917	Prolactin signaling pathway	11/495	87/7206	0.0498139168801