ko	pathway	ratio_in_study	ratio_in_pop	p_value
ko04724	Glutamatergic synapse	78/745	152/7206	8.11318368501e-38
ko05033	Nicotine addiction	43/745	56/7206	7.03769771974e-32
ko04080	Neuroactive ligand-receptor interaction	124/745	423/7206	1.71611475076e-29
ko05032	Morphine addiction	54/745	110/7206	3.6923253008e-25
ko04727	GABAergic synapse	53/745	110/7206	3.2529061105e-24
ko04713	Circadian entrainment	58/745	136/7206	5.14269533367e-23
ko04723	Retrograde endocannabinoid signaling	64/745	175/7206	5.69641729968e-21
ko04728	Dopaminergic synapse	63/745	185/7206	8.22140990754e-19
ko04725	Cholinergic synapse	54/745	160/7206	4.47239554824e-16
ko04020	Calcium signaling pathway	71/745	265/7206	9.45944698133e-15
ko04024	cAMP signaling pathway	73/745	279/7206	1.49044604712e-14
ko04720	Long-term potentiation	39/745	99/7206	1.87578084597e-14
ko04911	Insulin secretion	42/745	117/7206	8.19313110336e-14
ko05031	Amphetamine addiction	36/745	91/7206	1.66920616545e-13
ko05030	Cocaine addiction	31/745	73/7206	8.69555924179e-13
ko04921	Oxytocin signaling pathway	55/745	209/7206	2.48795363346e-11
ko04726	Serotonergic synapse	42/745	137/7206	3.27427647668e-11
ko04742	Taste transduction	25/745	61/7206	3.65857322231e-10
ko04721	Synaptic vesicle cycle	29/745	80/7206	4.7373071921e-10
ko04261	Adrenergic signaling in cardiomyocytes	52/745	205/7206	5.18881535512e-10
ko04925	Aldosterone synthesis and secretion	33/745	105/7206	2.15855142955e-09
ko04970	Salivary secretion	31/745	95/7206	2.3894595098e-09
ko04010	MAPK signaling pathway	67/745	321/7206	9.92103918717e-09
ko04730	Long-term depression	25/745	78/7206	1.27325626706e-07
ko04070	Phosphatidylinositol signaling system	31/745	112/7206	1.78432453618e-07
ko04060	Cytokine-cytokine receptor interaction	2/745	191/7206	3.74774268461e-07
ko04972	Pancreatic secretion	29/745	111/7206	1.64879608146e-06
ko04072	Phospholipase D signaling pathway	43/745	197/7206	2.06808911983e-06
ko05203	Viral carcinogenesis	8/745	277/7206	2.7951084634e-06
ko04915	Estrogen signaling pathway	32/745	131/7206	2.92411031913e-06
ko04022	cGMP-PKG signaling pathway	44/745	216/7206	1.09560198069e-05
ko05014	Amyotrophic lateral sclerosis (ALS)	21/745	74/7206	1.13093229984e-05
ko04971	Gastric acid secretion	25/745	98/7206	1.3477074516e-05
ko04744	Phototransduction	13/745	36/7206	3.34550991691e-05
ko04540	Gap junction	28/745	128/7206	9.90692963254e-05
ko05168	Herpes simplex infection	5/745	182/7206	0.000171777450808
ko04110	Cell cycle	3/745	145/7206	0.000254922924357
ko05414	Dilated cardiomyopathy	24/745	112/7206	0.000441721137587
ko04918	Thyroid hormone synthesis	20/745	86/7206	0.00045275110345
ko05322	Systemic lupus erythematosus	4/745	151/7206	0.000601444016357
ko00562	Inositol phosphate metabolism	20/745	89/7206	0.000657564574116
ko04750	Inflammatory mediator regulation of TRP channels	25/745	122/7206	0.000759752998539
ko05412	Arrhythmogenic right ventricular cardiomyopathy (ARVC)	18/745	79/7206	0.00110660513109
ko04740	Olfactory transduction	18/745	80/7206	0.0012465374932
ko00240	Pyrimidine metabolism	2/745	110/7206	0.00125145993939
ko04350	TGF-beta signaling pathway	2/745	103/7206	0.00171249516795
ko04932	Non-alcoholic fatty liver disease (NAFLD)	7/745	182/7206	0.0018659229917
ko04961	Endocrine and other factor-regulated calcium reabsorption	14/745	59/7206	0.00223893594289
ko04912	GnRH signaling pathway	24/745	122/7206	0.00224118537389
ko05231	Choline metabolism in cancer	25/745	134/7206	0.00362321070025
ko04745	Phototransduction - fly	10/745	38/7206	0.00421500211106
ko04141	Protein processing in endoplasmic reticulum	8/745	184/7206	0.00449036504887
ko04514	Cell adhesion molecules (CAMs)	24/745	130/7206	0.00505082498196
ko04923	Regulation of lipolysis in adipocytes	16/745	77/7206	0.00686790993232
ko04924	Renin secretion	17/745	86/7206	0.00708974498351
ko05169	Epstein-Barr virus infection	10/745	206/7206	0.00711455735001
ko00604	Glycosphingolipid biosynthesis - ganglio series	5/745	14/7206	0.0105324020968
ko04930	Type II diabetes mellitus	12/745	54/7206	0.0105749281738
ko04270	Vascular smooth muscle contraction	26/745	154/7206	0.0105833219104
ko00515	Mannose type O-glycan biosynthesis	7/745	25/7206	0.0111650161503
ko04320	Dorso-ventral axis formation	8/745	31/7206	0.0114540955394
ko04371	Apelin signaling pathway	29/745	177/7206	0.0117737458966
ko05110	Vibrio cholerae infection	13/745	63/7206	0.0119961371625
ko05034	Alcoholism	37/745	238/7206	0.0121885110472
ko05205	Proteoglycans in cancer	16/745	271/7206	0.0141354893738
ko04360	Axon guidance	36/745	233/7206	0.0154469972511
ko04260	Cardiac muscle contraction	18/745	98/7206	0.0174917189948
ko04145	Phagosome	8/745	162/7206	0.0184840774205
ko05202	Transcriptional misregulation in cancer	10/745	188/7206	0.0204029786971
ko05418	Fluid shear stress and atherosclerosis	9/745	173/7206	0.0222914777019
ko05162	Measles	5/745	120/7206	0.0223105791524
ko04062	Chemokine signaling pathway	31/745	201/7206	0.0246085067851
ko00512	Mucin type O-glycan biosynthesis	7/745	29/7206	0.0252229340838
ko04916	Melanogenesis	23/745	142/7206	0.0256274670946
ko05321	Inflammatory bowel disease (IBD)	1/745	56/7206	0.0268458044952
ko04630	Jak-STAT signaling pathway	6/745	132/7206	0.0288991049524
ko04914	Progesterone-mediated oocyte maturation	18/745	104/7206	0.0326943042637
ko00510	N-Glycan biosynthesis	10/745	50/7206	0.0337906933066
ko00513	Various types of N-glycan biosynthesis	9/745	42/7206	0.0353104309466
ko04071	Sphingolipid signaling pathway	25/745	162/7206	0.0365160519539
ko04550	Signaling pathways regulating pluripotency of stem cells	9/745	165/7206	0.0375456501093
ko03013	RNA transport	9/745	166/7206	0.037823006342
ko04711	Circadian rhythm - fly	4/745	13/7206	0.037895630872
ko00190	Oxidative phosphorylation	6/745	127/7206	0.0379719461537
ko05164	Influenza A	9/745	167/7206	0.0382365017627
ko04012	ErbB signaling pathway	18/745	109/7206	0.0389973603157
ko00480	Glutathione metabolism	1/745	55/7206	0.0409955340079
ko04940	Type I diabetes mellitus	7/745	32/7206	0.041528025292
ko04976	Bile secretion	14/745	80/7206	0.0416326240373
ko05223	Non-small cell lung cancer	12/745	66/7206	0.0423548222448
ko04064	NF-kappa B signaling pathway	4/745	96/7206	0.0424332693531
ko05131	Shigellosis	3/745	82/7206	0.0437464470854
ko04015	Rap1 signaling pathway	39/745	278/7206	0.04424205918
ko03018	RNA degradation	3/745	84/7206	0.0446868427247
ko04014	Ras signaling pathway	39/745	279/7206	0.0449821733698
ko00430	Taurine and hypotaurine metabolism	4/745	14/7206	0.0488409223824