ko	pathway	ratio_in_study	ratio_in_pop	p_value
ko04080	Neuroactive ligand-receptor interaction	196/1225	423/7206	5.79175648409e-48
ko04724	Glutamatergic synapse	88/1225	152/7206	1.17279516881e-30
ko05033	Nicotine addiction	46/1225	56/7206	1.20064081005e-26
ko04713	Circadian entrainment	73/1225	136/7206	7.62195674422e-23
ko05032	Morphine addiction	63/1225	110/7206	7.12090231071e-22
ko04727	GABAergic synapse	61/1225	110/7206	3.1159768244e-20
ko04728	Dopaminergic synapse	83/1225	185/7206	2.8107063727e-19
ko04020	Calcium signaling pathway	104/1225	265/7206	1.51676108694e-18
ko04721	Synaptic vesicle cycle	46/1225	80/7206	2.17980203621e-16
ko04723	Retrograde endocannabinoid signaling	75/1225	175/7206	3.66969737396e-16
ko04725	Cholinergic synapse	70/1225	160/7206	1.00297357175e-15
ko04024	cAMP signaling pathway	101/1225	279/7206	3.2453636526e-15
ko04911	Insulin secretion	56/1225	117/7206	6.84723643035e-15
ko04726	Serotonergic synapse	60/1225	137/7206	1.12299352673e-13
ko04921	Oxytocin signaling pathway	78/1225	209/7206	8.49748540746e-13
ko04742	Taste transduction	35/1225	61/7206	9.72969647038e-13
ko05031	Amphetamine addiction	41/1225	91/7206	3.20852408142e-10
ko04720	Long-term potentiation	43/1225	99/7206	4.98086790567e-10
ko03010	Ribosome	1/1225	129/7206	1.54074254366e-09
ko04970	Salivary secretion	41/1225	95/7206	1.59833934786e-09
ko04261	Adrenergic signaling in cardiomyocytes	68/1225	205/7206	1.26507574519e-08
ko04744	Phototransduction	21/1225	36/7206	2.45378850146e-08
ko04022	cGMP-PKG signaling pathway	69/1225	216/7206	5.42800065886e-08
ko04925	Aldosterone synthesis and secretion	41/1225	105/7206	5.52027791319e-08
ko03040	Spliceosome	4/1225	145/7206	7.98569276337e-08
ko05322	Systemic lupus erythematosus	5/1225	151/7206	2.49806325365e-07
ko04971	Gastric acid secretion	37/1225	98/7206	8.52021673828e-07
ko05168	Herpes simplex infection	9/1225	182/7206	1.08847446726e-06
ko05203	Viral carcinogenesis	20/1225	277/7206	1.79408452468e-06
ko03013	RNA transport	8/1225	166/7206	2.87157586036e-06
ko04730	Long-term depression	30/1225	78/7206	5.09895023327e-06
ko04070	Phosphatidylinositol signaling system	38/1225	112/7206	1.0754352496e-05
ko05030	Cocaine addiction	28/1225	73/7206	1.13704396633e-05
ko04360	Axon guidance	66/1225	233/7206	1.15070629088e-05
ko05014	Amyotrophic lateral sclerosis (ALS)	28/1225	74/7206	1.47687728686e-05
ko04120	Ubiquitin mediated proteolysis	7/1225	138/7206	3.06948187384e-05
ko04621	NOD-like receptor signaling pathway	9/1225	157/7206	3.51893645972e-05
ko04010	MAPK signaling pathway	83/1225	321/7206	3.74986477134e-05
ko04514	Cell adhesion molecules (CAMs)	41/1225	130/7206	4.50226007613e-05
ko04072	Phospholipase D signaling pathway	56/1225	197/7206	4.6586745466e-05
ko04110	Cell cycle	8/1225	145/7206	4.67983052368e-05
ko04972	Pancreatic secretion	36/1225	111/7206	5.86721998901e-05
ko04745	Phototransduction - fly	17/1225	38/7206	5.88117495877e-05
ko05164	Influenza A	11/1225	167/7206	9.69908401172e-05
ko04966	Collecting duct acid secretion	13/1225	26/7206	0.000108343214178
ko03008	Ribosome biogenesis in eukaryotes	2/1225	79/7206	0.000111156902781
ko04740	Olfactory transduction	28/1225	80/7206	0.000119022336735
ko04060	Cytokine-cytokine receptor interaction	14/1225	191/7206	0.000121694468735
ko04540	Gap junction	39/1225	128/7206	0.000184798733623
ko04750	Inflammatory mediator regulation of TRP channels	37/1225	122/7206	0.000226143300936
ko04976	Bile secretion	27/1225	80/7206	0.000240758289125
ko04014	Ras signaling pathway	71/1225	279/7206	0.00031896116964
ko04710	Circadian rhythm	17/1225	43/7206	0.000367419950109
ko05161	Hepatitis B	13/1225	173/7206	0.000434550177511
ko05412	Arrhythmogenic right ventricular cardiomyopathy (ARVC)	26/1225	79/7206	0.000452322365677
ko04270	Vascular smooth muscle contraction	43/1225	154/7206	0.000680508635943
ko04371	Apelin signaling pathway	48/1225	177/7206	0.000740606904444
ko04922	Glucagon signaling pathway	37/1225	128/7206	0.000765557755447
ko04064	NF-kappa B signaling pathway	5/1225	96/7206	0.000873857021741
ko05169	Epstein-Barr virus infection	18/1225	206/7206	0.000908486622014
ko04915	Estrogen signaling pathway	37/1225	131/7206	0.00134737861555
ko04141	Protein processing in endoplasmic reticulum	16/1225	184/7206	0.00140810377368
ko04964	Proximal tubule bicarbonate reclamation	12/1225	29/7206	0.00167474129809
ko04260	Cardiac muscle contraction	29/1225	98/7206	0.00168645937955
ko05110	Vibrio cholerae infection	21/1225	63/7206	0.00189803687559
ko04924	Renin secretion	26/1225	86/7206	0.00214817141473
ko04630	Jak-STAT signaling pathway	10/1225	132/7206	0.00221187205717
ko03420	Nucleotide excision repair	1/1225	46/7206	0.00284833802519
ko04930	Type II diabetes mellitus	18/1225	54/7206	0.00305269075154
ko05162	Measles	9/1225	120/7206	0.00315810161795
ko04612	Antigen processing and presentation	4/1225	77/7206	0.00332464081322
ko03022	Basal transcription factors	1/1225	44/7206	0.00427038825767
ko05144	Malaria	1/1225	45/7206	0.00434417527943
ko05140	Leishmaniasis	4/1225	75/7206	0.00477792896045
ko05414	Dilated cardiomyopathy	31/1225	112/7206	0.00482222155073
ko00280	Valine, leucine and isoleucine degradation	2/1225	54/7206	0.00555419822891
ko04626	Plant-pathogen interaction	8/1225	18/7206	0.00598217686035
ko04217	Necroptosis	17/1225	178/7206	0.00612691995091
ko04622	RIG-I-like receptor signaling pathway	3/1225	62/7206	0.00626391694121
ko04960	Aldosterone-regulated sodium reabsorption	14/1225	41/7206	0.0063085007332
ko04610	Complement and coagulation cascades	5/1225	79/7206	0.00956062650561
ko05205	Proteoglycans in cancer	31/1225	271/7206	0.0131115171037
ko05166	HTLV-I infection	34/1225	292/7206	0.0134011619731
ko04015	Rap1 signaling pathway	63/1225	278/7206	0.0142695683718
ko00630	Glyoxylate and dicarboxylate metabolism	1/1225	38/7206	0.0149263140066
ko03410	Base excision repair	1/1225	38/7206	0.0149263140066
ko00562	Inositol phosphate metabolism	24/1225	89/7206	0.015550977708
ko05321	Inflammatory bowel disease (IBD)	3/1225	56/7206	0.0186049481633
ko04912	GnRH signaling pathway	31/1225	122/7206	0.0200315097025
ko04142	Lysosome	15/1225	151/7206	0.020804501831
ko05016	Huntington's disease	24/1225	215/7206	0.0208150254386
ko00604	Glycosphingolipid biosynthesis - ganglio series	6/1225	14/7206	0.0208228978803
ko04657	IL-17 signaling pathway	7/1225	87/7206	0.0214832710393
ko05133	Pertussis	7/1225	87/7206	0.0214832710393
ko00860	Porphyrin and chlorophyll metabolism	1/1225	34/7206	0.021723494424
ko05410	Hypertrophic cardiomyopathy (HCM)	26/1225	100/7206	0.0218369008774
ko04146	Peroxisome	7/1225	89/7206	0.0219061647149
ko05222	Small cell lung cancer	7/1225	89/7206	0.0219061647149
ko04973	Carbohydrate digestion and absorption	13/1225	42/7206	0.0224190248246
ko05145	Toxoplasmosis	12/1225	126/7206	0.0225982072559
ko00590	Arachidonic acid metabolism	3/1225	52/7206	0.0258792526076
ko04932	Non-alcoholic fatty liver disease (NAFLD)	20/1225	182/7206	0.0276662419341
ko00240	Pyrimidine metabolism	10/1225	110/7206	0.028604247337
ko04916	Melanogenesis	34/1225	142/7206	0.031590616196
ko04210	Apoptosis	20/1225	180/7206	0.0343531189675
ko05231	Choline metabolism in cancer	32/1225	134/7206	0.0366022229522
ko05230	Central carbon metabolism in cancer	21/1225	81/7206	0.0370893262694
ko04668	TNF signaling pathway	12/1225	120/7206	0.0373061791356
ko05131	Shigellosis	7/1225	82/7206	0.0382843646619
ko04114	Oocyte meiosis	33/1225	139/7206	0.0395103184956
ko05340	Primary immunodeficiency	1/1225	30/7206	0.0486581755667