ko	pathway	ratio_in_study	ratio_in_pop	p_value
ko04080	Neuroactive ligand-receptor interaction	166/1011	423/7206	1.62657881616e-40
ko04724	Glutamatergic synapse	78/1011	152/7206	2.54096672195e-28
ko05033	Nicotine addiction	44/1011	56/7206	1.33078287105e-27
ko05032	Morphine addiction	60/1011	110/7206	7.91300311212e-24
ko04728	Dopaminergic synapse	77/1011	185/7206	1.01004458475e-20
ko04727	GABAergic synapse	56/1011	110/7206	2.15257277152e-20
ko04713	Circadian entrainment	60/1011	136/7206	7.49400391808e-18
ko04721	Synaptic vesicle cycle	43/1011	80/7206	4.37645238265e-17
ko04723	Retrograde endocannabinoid signaling	68/1011	175/7206	1.53172773998e-16
ko04024	cAMP signaling pathway	91/1011	279/7206	7.61956123995e-16
ko04725	Cholinergic synapse	61/1011	160/7206	1.65936566815e-14
ko04360	Axon guidance	77/1011	233/7206	6.03026367511e-14
ko04726	Serotonergic synapse	50/1011	137/7206	2.72071743991e-11
ko04742	Taste transduction	30/1011	61/7206	5.09151486009e-11
ko04020	Calcium signaling pathway	77/1011	265/7206	9.68162978122e-11
ko04911	Insulin secretion	44/1011	117/7206	1.38796840503e-10
ko04744	Phototransduction	21/1011	36/7206	6.89404008897e-10
ko05031	Amphetamine addiction	34/1011	91/7206	2.14135252257e-08
ko04921	Oxytocin signaling pathway	60/1011	209/7206	2.22308309225e-08
ko04261	Adrenergic signaling in cardiomyocytes	59/1011	205/7206	2.939725241e-08
ko05203	Viral carcinogenesis	12/1011	277/7206	1.27874712342e-07
ko03040	Spliceosome	2/1011	145/7206	1.62881256688e-07
ko05030	Cocaine addiction	28/1011	73/7206	1.9877313516e-07
ko04010	MAPK signaling pathway	77/1011	321/7206	9.63882628428e-07
ko04720	Long-term potentiation	33/1011	99/7206	1.05258162766e-06
ko03013	RNA transport	5/1011	166/7206	2.38619171964e-06
ko04970	Salivary secretion	30/1011	95/7206	8.96368191694e-06
ko05014	Amyotrophic lateral sclerosis (ALS)	25/1011	74/7206	1.27947061107e-05
ko05322	Systemic lupus erythematosus	5/1011	151/7206	1.50580344342e-05
ko04514	Cell adhesion molecules (CAMs)	37/1011	130/7206	1.63529043431e-05
ko04740	Olfactory transduction	25/1011	80/7206	6.2384061213e-05
ko04141	Protein processing in endoplasmic reticulum	9/1011	184/7206	8.87279719686e-05
ko04060	Cytokine-cytokine receptor interaction	10/1011	191/7206	0.000122998817398
ko03008	Ribosome biogenesis in eukaryotes	1/1011	79/7206	0.00013048654254
ko04022	cGMP-PKG signaling pathway	51/1011	216/7206	0.000132856412028
ko00604	Glycosphingolipid biosynthesis - ganglio series	8/1011	14/7206	0.000199820958389
ko04014	Ras signaling pathway	61/1011	279/7206	0.00028554950328
ko04120	Ubiquitin mediated proteolysis	6/1011	138/7206	0.000287960446409
ko04146	Peroxisome	2/1011	89/7206	0.000305125483765
ko04260	Cardiac muscle contraction	27/1011	98/7206	0.000362206731957
ko04730	Long-term depression	23/1011	78/7206	0.000392717898912
ko05412	Arrhythmogenic right ventricular cardiomyopathy (ARVC)	23/1011	79/7206	0.000446751651873
ko04391	Hippo signaling pathway - fly	25/1011	90/7206	0.000592645476714
ko03018	RNA degradation	2/1011	84/7206	0.000680910905463
ko05168	Herpes simplex infection	11/1011	182/7206	0.00076084202605
ko04972	Pancreatic secretion	29/1011	111/7206	0.000763538292182
ko04971	Gastric acid secretion	26/1011	98/7206	0.00103217212193
ko04612	Antigen processing and presentation	2/1011	77/7206	0.00141106348275
ko05164	Influenza A	10/1011	167/7206	0.00144770091308
ko04621	NOD-like receptor signaling pathway	9/1011	157/7206	0.0015239267125
ko04966	Collecting duct acid secretion	10/1011	26/7206	0.00177313725843
ko00240	Pyrimidine metabolism	5/1011	110/7206	0.00206908646274
ko05162	Measles	6/1011	120/7206	0.00211540813824
ko04072	Phospholipase D signaling pathway	43/1011	197/7206	0.00242483979261
ko04064	NF-kappa B signaling pathway	4/1011	96/7206	0.0027372421371
ko04925	Aldosterone synthesis and secretion	26/1011	105/7206	0.00275679023321
ko04745	Phototransduction - fly	12/1011	38/7206	0.00438906955069
ko00480	Glutathione metabolism	1/1011	55/7206	0.0051528322177
ko05205	Proteoglycans in cancer	23/1011	271/7206	0.00563900132831
ko05110	Vibrio cholerae infection	17/1011	63/7206	0.00569895002614
ko04640	Hematopoietic cell lineage	2/1011	64/7206	0.00632852269076
ko00534	Glycosaminoglycan biosynthesis - heparan sulfate / heparin	9/1011	26/7206	0.00674774926745
ko04540	Gap junction	29/1011	128/7206	0.00683661721634
ko05140	Leishmaniasis	3/1011	75/7206	0.00715632834132
ko04961	Endocrine and other factor-regulated calcium reabsorption	16/1011	59/7206	0.0073142314188
ko00590	Arachidonic acid metabolism	1/1011	52/7206	0.00763515820539
ko05169	Epstein-Barr virus infection	16/1011	206/7206	0.00777512661322
ko04070	Phosphatidylinositol signaling system	26/1011	112/7206	0.00847599972773
ko04930	Type II diabetes mellitus	15/1011	54/7206	0.00870953853226
ko01200	Carbon metabolism	8/1011	128/7206	0.00952984935719
ko00270	Cysteine and methionine metabolism	1/1011	47/7206	0.0109323716369
ko00260	Glycine, serine and threonine metabolism	1/1011	48/7206	0.0109801692349
ko04924	Renin secretion	21/1011	86/7206	0.0112277676204
ko00533	Glycosaminoglycan biosynthesis - keratan sulfate	6/1011	15/7206	0.0121407352754
ko04932	Non-alcoholic fatty liver disease (NAFLD)	14/1011	182/7206	0.0123629678112
ko04964	Proximal tubule bicarbonate reclamation	9/1011	29/7206	0.014656937639
ko03022	Basal transcription factors	1/1011	44/7206	0.0162223319374
ko05144	Malaria	1/1011	45/7206	0.0162702579807
ko00071	Fatty acid degradation	1/1011	45/7206	0.0162702579807
ko00620	Pyruvate metabolism	1/1011	46/7206	0.0167068471384
ko05414	Dilated cardiomyopathy	25/1011	112/7206	0.018589745551
ko05321	Inflammatory bowel disease (IBD)	2/1011	56/7206	0.0191344055408
ko04915	Estrogen signaling pathway	28/1011	131/7206	0.0213531349498
ko04110	Cell cycle	11/1011	145/7206	0.0214014846769
ko00140	Steroid hormone biosynthesis	1/1011	41/7206	0.0240234684933
ko00983	Drug metabolism - other enzymes	1/1011	42/7206	0.024068279752
ko04711	Circadian rhythm - fly	5/1011	13/7206	0.0261392900756
ko04115	p53 signaling pathway	4/1011	74/7206	0.0280997511778
ko04350	TGF-beta signaling pathway	7/1011	103/7206	0.0314363104545
ko00630	Glyoxylate and dicarboxylate metabolism	1/1011	38/7206	0.0354952125971
ko00980	Metabolism of xenobiotics by cytochrome P450	1/1011	40/7206	0.0363432545203
ko04722	Neurotrophin signaling pathway	32/1011	160/7206	0.0372693137141
ko04071	Sphingolipid signaling pathway	32/1011	162/7206	0.0391347188171
ko00380	Tryptophan metabolism	2/1011	50/7206	0.039320877065
ko04611	Platelet activation	14/1011	163/7206	0.0402685884378
ko05210	Colorectal cancer	19/1011	86/7206	0.0406317238672
ko05146	Amoebiasis	7/1011	99/7206	0.0415413264862
ko05231	Choline metabolism in cancer	27/1011	134/7206	0.0444377466855
ko04510	Focal adhesion	23/1011	240/7206	0.0466069993384
ko05120	Epithelial cell signaling in Helicobacter pylori infection	20/1011	92/7206	0.0474687205374
ko04750	Inflammatory mediator regulation of TRP channels	25/1011	122/7206	0.0474794573169