ko	pathway	ratio_in_study	ratio_in_pop	p_value
ko04080	Neuroactive ligand-receptor interaction	207/1305	423/7206	7.60569347416e-51
ko04724	Glutamatergic synapse	94/1305	152/7206	1.15880438552e-33
ko05033	Nicotine addiction	48/1305	56/7206	3.66896308353e-28
ko04727	GABAergic synapse	69/1305	110/7206	1.76489208753e-25
ko05032	Morphine addiction	69/1305	110/7206	1.76489208753e-25
ko04713	Circadian entrainment	78/1305	136/7206	5.13202380823e-25
ko04728	Dopaminergic synapse	88/1305	185/7206	1.38774343092e-20
ko04721	Synaptic vesicle cycle	50/1305	80/7206	1.10864186095e-18
ko04020	Calcium signaling pathway	108/1305	265/7206	1.46687565861e-18
ko04725	Cholinergic synapse	75/1305	160/7206	3.02213658802e-17
ko04024	cAMP signaling pathway	109/1305	279/7206	5.64736603579e-17
ko04723	Retrograde endocannabinoid signaling	79/1305	175/7206	6.53750044382e-17
ko04726	Serotonergic synapse	65/1305	137/7206	1.99413829988e-15
ko04744	Phototransduction	26/1305	36/7206	1.60365093753e-12
ko04742	Taste transduction	35/1305	61/7206	6.55204109344e-12
ko04911	Insulin secretion	53/1305	117/7206	8.01566672509e-12
ko04921	Oxytocin signaling pathway	79/1305	209/7206	8.26196168304e-12
ko05031	Amphetamine addiction	44/1305	91/7206	3.33223435453e-11
ko03010	Ribosome	1/1305	129/7206	2.09861896757e-10
ko04720	Long-term potentiation	44/1305	99/7206	1.03324982999e-09
ko04022	cGMP-PKG signaling pathway	75/1305	216/7206	2.90471464498e-09
ko04261	Adrenergic signaling in cardiomyocytes	71/1305	205/7206	1.01211768773e-08
ko04970	Salivary secretion	41/1305	95/7206	1.60204421795e-08
ko03040	Spliceosome	4/1305	145/7206	2.05319089793e-08
ko05322	Systemic lupus erythematosus	5/1305	151/7206	4.34879564471e-08
ko04925	Aldosterone synthesis and secretion	42/1305	105/7206	1.19404559776e-07
ko05030	Cocaine addiction	32/1305	73/7206	2.93193427712e-07
ko03013	RNA transport	8/1305	166/7206	5.98319564059e-07
ko05203	Viral carcinogenesis	21/1305	277/7206	6.07621043868e-07
ko04070	Phosphatidylinositol signaling system	41/1305	112/7206	2.78589620712e-06
ko04971	Gastric acid secretion	37/1305	98/7206	3.80469759219e-06
ko04740	Olfactory transduction	32/1305	80/7206	5.36391879233e-06
ko05168	Herpes simplex infection	12/1305	182/7206	8.92304087447e-06
ko04110	Cell cycle	8/1305	145/7206	1.54514903417e-05
ko05014	Amyotrophic lateral sclerosis (ALS)	29/1305	74/7206	2.16618442926e-05
ko04966	Collecting duct acid secretion	14/1305	26/7206	4.16892497182e-05
ko03008	Ribosome biogenesis in eukaryotes	2/1305	79/7206	4.49814843326e-05
ko04072	Phospholipase D signaling pathway	59/1305	197/7206	4.53330183728e-05
ko04924	Renin secretion	31/1305	86/7206	6.14088833734e-05
ko04710	Circadian rhythm	19/1305	43/7206	6.70214491384e-05
ko04730	Long-term depression	29/1305	78/7206	7.58307331967e-05
ko04010	MAPK signaling pathway	86/1305	321/7206	7.87532113889e-05
ko04060	Cytokine-cytokine receptor interaction	15/1305	191/7206	7.96503819319e-05
ko04621	NOD-like receptor signaling pathway	11/1305	157/7206	8.82738355167e-05
ko04745	Phototransduction - fly	17/1305	38/7206	0.000133872341646
ko04141	Protein processing in endoplasmic reticulum	15/1305	184/7206	0.000142866902923
ko04270	Vascular smooth muscle contraction	47/1305	154/7206	0.000178432992261
ko04514	Cell adhesion molecules (CAMs)	41/1305	130/7206	0.000192820542832
ko04014	Ras signaling pathway	75/1305	279/7206	0.000242598769963
ko04972	Pancreatic secretion	36/1305	111/7206	0.000254222639366
ko04540	Gap junction	40/1305	128/7206	0.000278481074047
ko00520	Amino sugar and nucleotide sugar metabolism	1/1305	55/7206	0.000328041649244
ko05169	Epstein-Barr virus infection	19/1305	206/7206	0.000444529688284
ko04923	Regulation of lipolysis in adipocytes	27/1305	77/7206	0.000464419043544
ko04750	Inflammatory mediator regulation of TRP channels	38/1305	122/7206	0.000490797668048
ko05164	Influenza A	14/1305	167/7206	0.000495791853188
ko05161	Hepatitis B	15/1305	173/7206	0.000618759822907
ko04360	Axon guidance	63/1305	233/7206	0.0006875211943
ko04371	Apelin signaling pathway	50/1305	177/7206	0.000732170736288
ko04120	Ubiquitin mediated proteolysis	11/1305	138/7206	0.00108573777935
ko04922	Glucagon signaling pathway	38/1305	128/7206	0.00111862632725
ko04915	Estrogen signaling pathway	39/1305	131/7206	0.00118901338764
ko03420	Nucleotide excision repair	1/1305	46/7206	0.00175530366576
ko03022	Basal transcription factors	1/1305	44/7206	0.00266606835136
ko05205	Proteoglycans in cancer	31/1305	271/7206	0.00285057273844
ko05412	Arrhythmogenic right ventricular cardiomyopathy (ARVC)	25/1305	79/7206	0.0030668153039
ko05166	HTLV-I infection	34/1305	292/7206	0.00308182990418
ko04214	Apoptosis - fly	4/1305	72/7206	0.00311525958739
ko04711	Circadian rhythm - fly	7/1305	13/7206	0.0038943173793
ko04330	Notch signaling pathway	3/1305	62/7206	0.00419251165537
ko04622	RIG-I-like receptor signaling pathway	3/1305	62/7206	0.00419251165537
ko05110	Vibrio cholerae infection	21/1305	63/7206	0.00441589836808
ko04064	NF-kappa B signaling pathway	7/1305	96/7206	0.00458586611351
ko04657	IL-17 signaling pathway	6/1305	87/7206	0.0046071069765
ko05133	Pertussis	6/1305	87/7206	0.0046071069765
ko04976	Bile secretion	25/1305	80/7206	0.00489285241843
ko04630	Jak-STAT signaling pathway	12/1305	132/7206	0.00579968118311
ko05414	Dilated cardiomyopathy	32/1305	112/7206	0.00612508111704
ko05140	Leishmaniasis	5/1305	75/7206	0.00639079286675
ko04930	Type II diabetes mellitus	18/1305	54/7206	0.00683544445373
ko05131	Shigellosis	6/1305	82/7206	0.00876117822806
ko04626	Plant-pathogen interaction	8/1305	18/7206	0.00886819906404
ko04672	Intestinal immune network for IgA production	1/1305	37/7206	0.00920857467197
ko03410	Base excision repair	1/1305	38/7206	0.00948479574399
ko04961	Endocrine and other factor-regulated calcium reabsorption	19/1305	59/7206	0.00961577857108
ko04658	Th1 and Th2 cell differentiation	8/1305	96/7206	0.0106358100634
ko05144	Malaria	2/1305	45/7206	0.0112744089114
ko04260	Cardiac muscle contraction	28/1305	98/7206	0.0113285552325
ko04610	Complement and coagulation cascades	6/1305	79/7206	0.0119472061321
ko00280	Valine, leucine and isoleucine degradation	3/1305	54/7206	0.0122607519571
ko04964	Proximal tubule bicarbonate reclamation	11/1305	29/7206	0.0123831733772
ko05416	Viral myocarditis	3/1305	55/7206	0.0125176839913
ko04960	Aldosterone-regulated sodium reabsorption	14/1305	41/7206	0.0130277849945
ko04217	Necroptosis	20/1305	178/7206	0.0136706501791
ko04973	Carbohydrate digestion and absorption	14/1305	42/7206	0.0152156943555
ko04612	Antigen processing and presentation	6/1305	77/7206	0.0164236473436
ko05162	Measles	12/1305	120/7206	0.0168043037292
ko04932	Non-alcoholic fatty liver disease (NAFLD)	21/1305	182/7206	0.0189691891111
ko00965	Betalain biosynthesis	3/1305	4/7206	0.0204984555588
ko05202	Transcriptional misregulation in cancer	22/1305	188/7206	0.0208660714952
ko05200	Pathways in cancer	70/1305	492/7206	0.0210431308171
ko04115	p53 signaling pathway	6/1305	74/7206	0.0222542029618
ko05231	Choline metabolism in cancer	35/1305	134/7206	0.0227564832201
ko04213	Longevity regulating pathway - multiple species	24/1305	86/7206	0.0234539077699
ko00240	Pyrimidine metabolism	11/1305	110/7206	0.0243429442856
ko05222	Small cell lung cancer	8/1305	89/7206	0.0256109503805
ko00604	Glycosphingolipid biosynthesis - ganglio series	6/1305	14/7206	0.0279294216663
ko05206	MicroRNAs in cancer	21/1305	177/7206	0.0292959279759
ko00480	Glutathione metabolism	4/1305	55/7206	0.0342993547106
ko05321	Inflammatory bowel disease (IBD)	4/1305	56/7206	0.0347596900758
ko05219	Bladder cancer	3/1305	48/7206	0.0361732587259
ko00562	Inositol phosphate metabolism	24/1305	89/7206	0.0368213181135
ko05130	Pathogenic Escherichia coli infection	7/1305	77/7206	0.0370681382407
ko04113	Meiosis - yeast	6/1305	70/7206	0.0411086544519
ko00680	Methane metabolism	11/1305	34/7206	0.0419833333632
ko04912	GnRH signaling pathway	31/1305	122/7206	0.0430129594459
ko03018	RNA degradation	8/1305	84/7206	0.044700392261
ko05145	Toxoplasmosis	14/1305	126/7206	0.0462375764697
ko05215	Prostate cancer	12/1305	111/7206	0.0462847397958
ko05016	Huntington's disease	28/1305	215/7206	0.0481439180171