ko	pathway	ratio_in_study	ratio_in_pop	p_value
ko04080	Neuroactive ligand-receptor interaction	139/788	423/7206	1.80191114101e-36
ko04724	Glutamatergic synapse	75/788	152/7206	3.72361929972e-33
ko05033	Nicotine addiction	42/788	56/7206	2.04707449463e-29
ko04727	GABAergic synapse	54/788	110/7206	5.91061672914e-24
ko05032	Morphine addiction	54/788	110/7206	5.91061672914e-24
ko04723	Retrograde endocannabinoid signaling	65/788	175/7206	2.26422778069e-20
ko04713	Circadian entrainment	56/788	136/7206	3.60358595936e-20
ko04728	Dopaminergic synapse	66/788	185/7206	1.41029632389e-19
ko04024	cAMP signaling pathway	81/788	279/7206	1.68723504947e-17
ko04721	Synaptic vesicle cycle	38/788	80/7206	1.4098228747e-16
ko04725	Cholinergic synapse	54/788	160/7206	5.15532552429e-15
ko04911	Insulin secretion	41/788	117/7206	2.68716710096e-12
ko04742	Taste transduction	28/788	61/7206	4.33317818127e-12
ko04261	Adrenergic signaling in cardiomyocytes	57/788	205/7206	9.31805118566e-12
ko04726	Serotonergic synapse	43/788	137/7206	5.12722556029e-11
ko04020	Calcium signaling pathway	66/788	265/7206	6.09508151054e-11
ko05031	Amphetamine addiction	33/788	91/7206	1.3275662029e-10
ko04921	Oxytocin signaling pathway	55/788	209/7206	2.43225144921e-10
ko05030	Cocaine addiction	28/788	73/7206	7.6038228556e-10
ko04720	Long-term potentiation	33/788	99/7206	1.6698276114e-09
ko04744	Phototransduction	18/788	36/7206	5.57275746031e-09
ko04060	Cytokine-cytokine receptor interaction	3/788	191/7206	8.27824560429e-07
ko04072	Phospholipase D signaling pathway	45/788	197/7206	1.15320799868e-06
ko03040	Spliceosome	1/788	145/7206	1.31034930747e-06
ko04010	MAPK signaling pathway	64/788	321/7206	1.38255601341e-06
ko05014	Amyotrophic lateral sclerosis (ALS)	23/788	74/7206	2.02180198956e-06
ko05203	Viral carcinogenesis	9/788	277/7206	2.94007273293e-06
ko04970	Salivary secretion	26/788	95/7206	6.30158344834e-06
ko04972	Pancreatic secretion	29/788	111/7206	7.48456900178e-06
ko04514	Cell adhesion molecules (CAMs)	32/788	130/7206	1.09939819331e-05
ko04925	Aldosterone synthesis and secretion	27/788	105/7206	1.96061015217e-05
ko05412	Arrhythmogenic right ventricular cardiomyopathy (ARVC)	22/788	79/7206	2.39796156856e-05
ko04260	Cardiac muscle contraction	25/788	98/7206	4.62137560942e-05
ko05164	Influenza A	4/788	167/7206	4.76653231927e-05
ko05168	Herpes simplex infection	5/788	182/7206	5.72099443161e-05
ko04022	cGMP-PKG signaling pathway	43/788	216/7206	8.4975771837e-05
ko05414	Dilated cardiomyopathy	26/788	112/7206	0.000169287403063
ko03013	RNA transport	5/788	166/7206	0.000229943964557
ko04966	Collecting duct acid secretion	10/788	26/7206	0.000238397844898
ko05322	Systemic lupus erythematosus	4/788	151/7206	0.000292581165171
ko04730	Long-term depression	20/788	78/7206	0.00030848926897
ko04740	Olfactory transduction	20/788	80/7206	0.000371538004302
ko04971	Gastric acid secretion	23/788	98/7206	0.000421852701282
ko04915	Estrogen signaling pathway	27/788	131/7206	0.000985988122174
ko04110	Cell cycle	5/788	145/7206	0.00174681439796
ko03008	Ribosome biogenesis in eukaryotes	1/788	79/7206	0.00176049835078
ko04014	Ras signaling pathway	47/788	279/7206	0.00228415274675
ko00604	Glycosphingolipid biosynthesis - ganglio series	6/788	14/7206	0.00232424782863
ko04612	Antigen processing and presentation	1/788	77/7206	0.00265578063059
ko05169	Epstein-Barr virus infection	10/788	206/7206	0.00299433875465
ko04120	Ubiquitin mediated proteolysis	5/788	138/7206	0.00339435852948
ko05162	Measles	4/788	120/7206	0.00450075716488
ko05205	Proteoglycans in cancer	16/788	271/7206	0.00524646107785
ko04141	Protein processing in endoplasmic reticulum	9/788	184/7206	0.00557552238732
ko05034	Alcoholism	40/788	238/7206	0.0056802262349
ko04976	Bile secretion	17/788	80/7206	0.00608472173243
ko04745	Phototransduction - fly	10/788	38/7206	0.00629669552508
ko04371	Apelin signaling pathway	31/788	177/7206	0.0070227787351
ko05110	Vibrio cholerae infection	14/788	63/7206	0.00768240597582
ko04640	Hematopoietic cell lineage	1/788	64/7206	0.00835156875856
ko05410	Hypertrophic cardiomyopathy (HCM)	20/788	100/7206	0.00864675277157
ko04540	Gap junction	24/788	128/7206	0.00917020876693
ko04360	Axon guidance	38/788	233/7206	0.010248552877
ko04330	Notch signaling pathway	1/788	62/7206	0.0124608719836
ko05161	Hepatitis B	9/788	173/7206	0.0129565535405
ko04924	Renin secretion	17/788	86/7206	0.0137591495244
ko04621	NOD-like receptor signaling pathway	8/788	157/7206	0.0137700938197
ko04930	Type II diabetes mellitus	12/788	54/7206	0.0139993347026
ko05140	Leishmaniasis	2/788	75/7206	0.0147888184268
ko04510	Focal adhesion	15/788	240/7206	0.0153145085744
ko04062	Chemokine signaling pathway	33/788	201/7206	0.0156491188019
ko04146	Peroxisome	3/788	89/7206	0.0159967005193
ko04350	TGF-beta signaling pathway	4/788	103/7206	0.0163416834967
ko04750	Inflammatory mediator regulation of TRP channels	22/788	122/7206	0.0180073073661
ko04214	Apoptosis - fly	2/788	72/7206	0.0212228260327
ko04550	Signaling pathways regulating pluripotency of stem cells	9/788	165/7206	0.0221719758876
ko00520	Amino sugar and nucleotide sugar metabolism	1/788	55/7206	0.0270556249717
ko00480	Glutathione metabolism	1/788	55/7206	0.0270556249717
ko05321	Inflammatory bowel disease (IBD)	1/788	56/7206	0.0279090519386
ko04071	Sphingolipid signaling pathway	27/788	162/7206	0.0291902107845
ko00240	Pyrimidine metabolism	5/788	110/7206	0.0297454956361
ko04932	Non-alcoholic fatty liver disease (NAFLD)	11/788	182/7206	0.0299733089833
ko05217	Basal cell carcinoma	2/788	68/7206	0.0301219313222
ko04015	Rap1 signaling pathway	42/788	278/7206	0.0303956745784
ko04070	Phosphatidylinositol signaling system	20/788	112/7206	0.0307503253302
ko04064	NF-kappa B signaling pathway	4/788	96/7206	0.0309028154966
ko04961	Endocrine and other factor-regulated calcium reabsorption	12/788	59/7206	0.0325694069739
ko00512	Mucin type O-glycan biosynthesis	7/788	29/7206	0.0331447960488
ko04964	Proximal tubule bicarbonate reclamation	7/788	29/7206	0.0331447960488
ko04630	Jak-STAT signaling pathway	7/788	132/7206	0.0341393393431
ko05166	HTLV-I infection	21/788	292/7206	0.0350290377863
ko00513	Various types of N-glycan biosynthesis	9/788	42/7206	0.0423771925172
ko04973	Carbohydrate digestion and absorption	9/788	42/7206	0.0423771925172
ko04140	Autophagy - animal	10/788	164/7206	0.0426811156636
ko05231	Choline metabolism in cancer	22/788	134/7206	0.0492169234384