ko	pathway	ratio_in_study	ratio_in_pop	p_value
ko04724	Glutamatergic synapse	53/662	152/7206	8.85792537845e-19
ko05033	Nicotine addiction	28/662	56/7206	3.46185509007e-15
ko04728	Dopaminergic synapse	52/662	185/7206	5.32735835536e-14
ko04727	GABAergic synapse	38/662	110/7206	1.22862454462e-13
ko04713	Circadian entrainment	42/662	136/7206	4.87361421812e-13
ko04721	Synaptic vesicle cycle	31/662	80/7206	6.84406208961e-13
ko05032	Morphine addiction	36/662	110/7206	3.48721541806e-12
ko04723	Retrograde endocannabinoid signaling	47/662	175/7206	5.57622701607e-12
ko04080	Neuroactive ligand-receptor interaction	82/662	423/7206	2.49263752687e-11
ko04725	Cholinergic synapse	43/662	160/7206	4.50465042461e-11
ko04911	Insulin secretion	35/662	117/7206	1.21940363498e-10
ko04024	cAMP signaling pathway	56/662	279/7206	1.560217082e-08
ko04261	Adrenergic signaling in cardiomyocytes	45/662	205/7206	2.01819651411e-08
ko04726	Serotonergic synapse	32/662	137/7206	5.02930274043e-07
ko04514	Cell adhesion molecules (CAMs)	30/662	130/7206	1.50262149467e-06
ko04260	Cardiac muscle contraction	24/662	98/7206	5.64840397865e-06
ko04744	Phototransduction	13/662	36/7206	9.28714499977e-06
ko05031	Amphetamine addiction	22/662	91/7206	1.72141511715e-05
ko04060	Cytokine-cytokine receptor interaction	3/662	191/7206	1.99761316268e-05
ko05030	Cocaine addiction	19/662	73/7206	2.10936236419e-05
ko05014	Amyotrophic lateral sclerosis (ALS)	19/662	74/7206	2.59900279918e-05
ko03040	Spliceosome	1/662	145/7206	2.74728682283e-05
ko04120	Ubiquitin mediated proteolysis	1/662	138/7206	3.82572145747e-05
ko05412	Arrhythmogenic right ventricular cardiomyopathy (ARVC)	19/662	79/7206	6.91014152558e-05
ko04512	ECM-receptor interaction	19/662	79/7206	6.91014152558e-05
ko05322	Systemic lupus erythematosus	2/662	151/7206	9.18534998605e-05
ko04360	Axon guidance	40/662	233/7206	0.000110487638252
ko04964	Proximal tubule bicarbonate reclamation	10/662	29/7206	0.000159072411003
ko05162	Measles	1/662	120/7206	0.000185218972476
ko05164	Influenza A	3/662	167/7206	0.000188087426824
ko04921	Oxytocin signaling pathway	36/662	209/7206	0.000210531158802
ko05203	Viral carcinogenesis	10/662	277/7206	0.000414919466489
ko04020	Calcium signaling pathway	42/662	265/7206	0.000450997613671
ko04974	Protein digestion and absorption	20/662	96/7206	0.000456314016864
ko04720	Long-term potentiation	20/662	99/7206	0.000625586374589
ko04010	MAPK signaling pathway	48/662	321/7206	0.000695825923353
ko04611	Platelet activation	4/662	163/7206	0.000885933228341
ko04140	Autophagy - animal	4/662	164/7206	0.000888480402454
ko04970	Salivary secretion	19/662	95/7206	0.000965615582148
ko05168	Herpes simplex infection	5/662	182/7206	0.000988608926532
ko04972	Pancreatic secretion	21/662	111/7206	0.00127195639564
ko05414	Dilated cardiomyopathy	21/662	112/7206	0.00137914675593
ko04022	cGMP-PKG signaling pathway	34/662	216/7206	0.00167840944318
ko04966	Collecting duct acid secretion	8/662	26/7206	0.00169910803078
ko05410	Hypertrophic cardiomyopathy (HCM)	19/662	100/7206	0.00233125551046
ko03013	RNA transport	5/662	166/7206	0.00259175732975
ko04742	Taste transduction	13/662	61/7206	0.00306937695027
ko04211	Longevity regulating pathway	3/662	123/7206	0.00648458094159
ko05010	Alzheimer's disease	30/662	202/7206	0.00880710247258
ko03008	Ribosome biogenesis in eukaryotes	1/662	79/7206	0.00923013071003
ko00240	Pyrimidine metabolism	3/662	110/7206	0.0121062869543
ko05215	Prostate cancer	3/662	111/7206	0.0121429810075
ko04916	Melanogenesis	22/662	142/7206	0.0123894765035
ko04214	Apoptosis - fly	1/662	72/7206	0.0130411911364
ko04146	Peroxisome	2/662	89/7206	0.0156527990779
ko04621	NOD-like receptor signaling pathway	6/662	157/7206	0.016548716815
ko01521	EGFR tyrosine kinase inhibitor resistance	3/662	106/7206	0.0169075166678
ko04976	Bile secretion	14/662	80/7206	0.0172548477849
ko04740	Olfactory transduction	14/662	80/7206	0.0172548477849
ko04150	mTOR signaling pathway	8/662	184/7206	0.0191724697883
ko04745	Phototransduction - fly	8/662	38/7206	0.0199349129201
ko04068	FoxO signaling pathway	7/662	167/7206	0.0205416185578
ko04971	Gastric acid secretion	16/662	98/7206	0.0206894081222
ko00230	Purine metabolism	9/662	194/7206	0.0229060821405
ko00561	Glycerolipid metabolism	1/662	63/7206	0.0277329989648
ko04730	Long-term depression	13/662	78/7206	0.0290691301679
ko04138	Autophagy - yeast	2/662	81/7206	0.0316029541723
ko05205	Proteoglycans in cancer	15/662	271/7206	0.0317754858182
ko04137	Mitophagy - animal	2/662	82/7206	0.0319720796242
ko00680	Methane metabolism	7/662	34/7206	0.0321039421725
ko04064	NF-kappa B signaling pathway	3/662	96/7206	0.0325405432487
ko05161	Hepatitis B	8/662	173/7206	0.0325838856048
ko04910	Insulin signaling pathway	8/662	172/7206	0.0325979585179
ko00604	Glycosphingolipid biosynthesis - ganglio series	4/662	14/7206	0.0334962700337
ko04151	PI3K-Akt signaling pathway	48/662	390/7206	0.0375116449305
ko04141	Protein processing in endoplasmic reticulum	9/662	184/7206	0.0383250434163
ko04925	Aldosterone synthesis and secretion	16/662	105/7206	0.0395362997189
ko05140	Leishmaniasis	2/662	75/7206	0.0443442833438
ko01524	Platinum drug resistance	2/662	76/7206	0.0444300522395
ko04612	Antigen processing and presentation	2/662	77/7206	0.044798815324
ko04371	Apelin signaling pathway	24/662	177/7206	0.0476069020798
ko04932	Non-alcoholic fatty liver disease (NAFLD)	9/662	182/7206	0.0497983489871