ko pathway ratio_in_study ratio_in_pop p_value ko04114 Oocyte meiosis 10/96 139/7206 1.41645882834e-05 ko04720 Long-term potentiation 8/96 99/7206 4.68063909195e-05 ko04722 Neurotrophin signaling pathway 10/96 160/7206 4.80391388413e-05 ko04626 Plant-pathogen interaction 4/96 18/7206 7.84489805353e-05 ko04745 Phototransduction - fly 5/96 38/7206 0.00013394441701 ko05031 Amphetamine addiction 7/96 91/7206 0.000194310196026 ko04014 Ras signaling pathway 12/96 279/7206 0.000305357948899 ko05130 Pathogenic Escherichia coli infection 6/96 77/7206 0.00052882998243 ko05214 Glioma 6/96 79/7206 0.000606890528079 ko04728 Dopaminergic synapse 9/96 185/7206 0.000755538723599 ko05167 Kaposi's sarcoma-associated herpesvirus infection 9/96 191/7206 0.000949048269912 ko04360 Axon guidance 10/96 233/7206 0.00101425804905 ko05203 Viral carcinogenesis 11/96 277/7206 0.00107117184868 ko04912 GnRH signaling pathway 7/96 122/7206 0.00115060723958 ko05034 Alcoholism 10/96 238/7206 0.00119229563184 ko04725 Cholinergic synapse 8/96 160/7206 0.00125522420963 ko05120 Epithelial cell signaling in Helicobacter pylori infection 6/96 92/7206 0.00135536502948 ko04062 Chemokine signaling pathway 9/96 201/7206 0.00135996133454 ko05211 Renal cell carcinoma 6/96 96/7206 0.00168861149418 ko05100 Bacterial invasion of epithelial cells 6/96 99/7206 0.00197690233637 ko04713 Circadian entrainment 7/96 136/7206 0.00215597950721 ko04371 Apelin signaling pathway 8/96 177/7206 0.00238189607943 ko05152 Tuberculosis 8/96 187/7206 0.00334618248154 ko04370 VEGF signaling pathway 5/96 77/7206 0.00350464917366 ko04024 cAMP signaling pathway 10/96 279/7206 0.00383780130131 ko04740 Olfactory transduction 5/96 80/7206 0.00413300308273 ko05212 Pancreatic cancer 5/96 83/7206 0.00483815222833 ko04151 PI3K-Akt signaling pathway 12/96 390/7206 0.00538048932103 ko04750 Inflammatory mediator regulation of TRP channels 6/96 122/7206 0.00558606288066 ko05210 Colorectal cancer 5/96 86/7206 0.00562497226152 ko04145 Phagosome 7/96 162/7206 0.00569122054097 ko04261 Adrenergic signaling in cardiomyocytes 8/96 205/7206 0.00582143708386 ko04662 B cell receptor signaling pathway 5/96 88/7206 0.00619727074836 ko04921 Oxytocin signaling pathway 8/96 209/7206 0.00652430445135 ko04922 Glucagon signaling pathway 6/96 128/7206 0.00703377335788 ko04540 Gap junction 6/96 128/7206 0.00703377335788 ko04910 Insulin signaling pathway 7/96 172/7206 0.00783590890717 ko04933 AGE-RAGE signaling pathway in diabetic complications 6/96 135/7206 0.00904667287034 ko04650 Natural killer cell mediated cytotoxicity 5/96 97/7206 0.00928547844538 ko04971 Gastric acid secretion 5/96 98/7206 0.00968378612665 ko05205 Proteoglycans in cancer 9/96 271/7206 0.00979036675445 ko04210 Apoptosis 7/96 180/7206 0.00994267366583 ko04310 Wnt signaling pathway 7/96 181/7206 0.0102325548487 ko04015 Rap1 signaling pathway 9/96 278/7206 0.0114527968146 ko04925 Aldosterone synthesis and secretion 5/96 105/7206 0.0128063521961 ko04270 Vascular smooth muscle contraction 6/96 154/7206 0.0165447629993 ko04070 Phosphatidylinositol signaling system 5/96 112/7206 0.0165504400655 ko04960 Aldosterone-regulated sodium reabsorption 3/96 41/7206 0.0169460927225 ko05169 Epstein-Barr virus infection 7/96 206/7206 0.0196595297457 ko04137 Mitophagy - animal 4/96 82/7206 0.0234794195144 ko04066 HIF-1 signaling pathway 5/96 123/7206 0.0237991735119 ko04660 T cell receptor signaling pathway 5/96 124/7206 0.0245452840346 ko04022 cGMP-PKG signaling pathway 7/96 216/7206 0.0247459005484 ko05133 Pertussis 4/96 87/7206 0.0284272054136 ko04016 MAPK signaling pathway - plant 2/96 20/7206 0.0285566737488 ko04915 Estrogen signaling pathway 5/96 131/7206 0.0301919685967 ko04218 Cellular senescence 6/96 177/7206 0.0303443404587 ko04726 Serotonergic synapse 5/96 137/7206 0.0356368201633 ko05200 Pathways in cancer 12/96 492/7206 0.03829985825 ko04916 Melanogenesis 5/96 142/7206 0.0406113659251 ko04961 Endocrine and other factor-regulated calcium reabsorption 3/96 59/7206 0.0435829367571 ko04110 Cell cycle 5/96 145/7206 0.0437895916745 ko04966 Collecting duct acid secretion 2/96 26/7206 0.0464031602712 ko04520 Adherens junction 4/96 103/7206 0.0481732460688