ko	pathway	ratio_in_study	ratio_in_pop	p_value
ko04080	Neuroactive ligand-receptor interaction	101/759	423/7206	2.99295974094e-16
ko05033	Nicotine addiction	28/759	56/7206	1.14875789465e-13
ko04260	Cardiac muscle contraction	36/759	98/7206	4.02596564845e-12
ko04721	Synaptic vesicle cycle	28/759	80/7206	3.65205427864e-09
ko04261	Adrenergic signaling in cardiomyocytes	50/759	205/7206	9.02217112152e-09
ko04727	GABAergic synapse	33/759	110/7206	1.28447500054e-08
ko04724	Glutamatergic synapse	40/759	152/7206	2.38928324304e-08
ko04728	Dopaminergic synapse	45/759	185/7206	6.30433535046e-08
ko05410	Hypertrophic cardiomyopathy (HCM)	29/759	100/7206	2.22218129186e-07
ko04911	Insulin secretion	32/759	117/7206	2.35481037183e-07
ko04950	Maturity onset diabetes of the young	14/759	29/7206	3.14663973021e-07
ko04713	Circadian entrainment	35/759	136/7206	3.2744742727e-07
ko04974	Protein digestion and absorption	27/759	96/7206	1.13525551412e-06
ko05414	Dilated cardiomyopathy	29/759	112/7206	2.93562406576e-06
ko04060	Cytokine-cytokine receptor interaction	4/759	191/7206	1.15921682099e-05
ko05032	Morphine addiction	27/759	110/7206	2.30047412702e-05
ko05203	Viral carcinogenesis	10/759	277/7206	2.33548513442e-05
ko05168	Herpes simplex infection	4/759	182/7206	2.37679172353e-05
ko04723	Retrograde endocannabinoid signaling	37/759	175/7206	2.76919534707e-05
ko04742	Taste transduction	18/759	61/7206	3.4276791675e-05
ko05162	Measles	1/759	120/7206	3.43782343434e-05
ko05412	Arrhythmogenic right ventricular cardiomyopathy (ARVC)	21/759	79/7206	4.45250614817e-05
ko04512	ECM-receptor interaction	21/759	79/7206	4.45250614817e-05
ko04010	MAPK signaling pathway	57/759	321/7206	5.59389828411e-05
ko04725	Cholinergic synapse	34/759	160/7206	6.43564240207e-05
ko03013	RNA transport	4/759	166/7206	0.000100437145322
ko05164	Influenza A	4/759	167/7206	0.000100904676522
ko05030	Cocaine addiction	19/759	73/7206	0.00013839675659
ko04978	Mineral absorption	13/759	40/7206	0.000142483701605
ko04976	Bile secretion	20/759	80/7206	0.000169611141542
ko04120	Ubiquitin mediated proteolysis	3/759	138/7206	0.000356715993743
ko04540	Gap junction	27/759	128/7206	0.000373747676694
ko04514	Cell adhesion molecules (CAMs)	27/759	130/7206	0.000449615470347
ko04360	Axon guidance	42/759	233/7206	0.000450470865668
ko04964	Proximal tubule bicarbonate reclamation	10/759	29/7206	0.000489964303401
ko04024	cAMP signaling pathway	48/759	279/7206	0.000642733465495
ko04140	Autophagy - animal	5/759	164/7206	0.000678988329419
ko05014	Amyotrophic lateral sclerosis (ALS)	18/759	74/7206	0.00076156631168
ko04921	Oxytocin signaling pathway	38/759	209/7206	0.000789756085251
ko04151	PI3K-Akt signaling pathway	62/759	390/7206	0.000874618354823
ko04621	NOD-like receptor signaling pathway	5/759	157/7206	0.000909802893551
ko04970	Salivary secretion	21/759	95/7206	0.00100917202034
ko04730	Long-term depression	18/759	78/7206	0.00115401301649
ko05166	HTLV-I infection	15/759	292/7206	0.00123788334818
ko04610	Complement and coagulation cascades	18/759	79/7206	0.00130633827541
ko05031	Amphetamine addiction	20/759	91/7206	0.00146877808032
ko05169	Epstein-Barr virus infection	9/759	206/7206	0.0017732933512
ko03008	Ribosome biogenesis in eukaryotes	1/759	79/7206	0.00266520489826
ko04141	Protein processing in endoplasmic reticulum	8/759	184/7206	0.00331277548485
ko05322	Systemic lupus erythematosus	6/759	151/7206	0.00468453170815
ko04142	Lysosome	6/759	151/7206	0.00468453170815
ko04740	Olfactory transduction	17/759	80/7206	0.00482918381276
ko04914	Progesterone-mediated oocyte maturation	3/759	104/7206	0.00584544245465
ko04217	Necroptosis	8/759	178/7206	0.00604893988045
ko04726	Serotonergic synapse	25/759	137/7206	0.006820852713
ko05152	Tuberculosis	9/759	187/7206	0.00749993360933
ko04110	Cell cycle	6/759	145/7206	0.00874292525776
ko04137	Mitophagy - animal	2/759	82/7206	0.0104983169659
ko04138	Autophagy - yeast	2/759	81/7206	0.0104993080933
ko04020	Calcium signaling pathway	41/759	265/7206	0.0105394545519
ko00430	Taurine and hypotaurine metabolism	5/759	14/7206	0.0113841997838
ko00564	Glycerophospholipid metabolism	3/759	99/7206	0.0120167845615
ko00561	Glycerolipid metabolism	1/759	63/7206	0.0124523349573
ko00600	Sphingolipid metabolism	1/759	63/7206	0.0124523349573
ko04218	Cellular senescence	9/759	177/7206	0.0129506745607
ko04145	Phagosome	27/759	162/7206	0.0136975133107
ko04062	Chemokine signaling pathway	11/759	201/7206	0.0142128280002
ko00250	Alanine, aspartate and glutamate metabolism	9/759	38/7206	0.015000975916
ko04612	Antigen processing and presentation	2/759	77/7206	0.0150075184134
ko04211	Longevity regulating pathway	5/759	123/7206	0.0165936098552
ko05161	Hepatitis B	9/759	173/7206	0.0169639738257
ko04022	cGMP-PKG signaling pathway	34/759	216/7206	0.0173767292534
ko04144	Endocytosis	23/759	342/7206	0.0185358453939
ko00350	Tyrosine metabolism	8/759	33/7206	0.0186013076329
ko05218	Melanoma	16/759	85/7206	0.0192874763877
ko04150	mTOR signaling pathway	10/759	184/7206	0.020240692421
ko04924	Renin secretion	16/759	86/7206	0.0205544039735
ko05134	Legionellosis	2/759	74/7206	0.0213681796493
ko05140	Leishmaniasis	2/759	75/7206	0.0215551086309
ko00520	Amino sugar and nucleotide sugar metabolism	1/759	55/7206	0.0266948580682
ko04961	Endocrine and other factor-regulated calcium reabsorption	12/759	59/7206	0.0292183370966
ko04214	Apoptosis - fly	2/759	72/7206	0.0311194116865
ko03018	RNA degradation	3/759	84/7206	0.0314167952948
ko00310	Lysine degradation	2/759	73/7206	0.0319219759838
ko04973	Carbohydrate digestion and absorption	9/759	42/7206	0.0372964834561
ko04064	NF-kappa B signaling pathway	4/759	96/7206	0.0426874617209
ko05224	Breast cancer	27/759	174/7206	0.044078411484
ko04630	Jak-STAT signaling pathway	7/759	132/7206	0.0451948380756