ko	pathway	ratio_in_study	ratio_in_pop	p_value
ko03040	Spliceosome	97/640	145/7206	1.37443483222e-68
ko03013	RNA transport	65/640	166/7206	5.41333748932e-27
ko04110	Cell cycle	57/640	145/7206	7.32625951511e-24
ko04111	Cell cycle - yeast	43/640	90/7206	2.83733018393e-22
ko03030	DNA replication	28/640	38/7206	4.18439153891e-22
ko00240	Pyrimidine metabolism	42/640	110/7206	2.6970652053e-17
ko03008	Ribosome biogenesis in eukaryotes	32/640	79/7206	2.54496042207e-14
ko03460	Fanconi anemia pathway	25/640	51/7206	8.87372719265e-14
ko04113	Meiosis - yeast	29/640	70/7206	2.12967336736e-13
ko03430	Mismatch repair	16/640	22/7206	5.64665938141e-13
ko03020	RNA polymerase	18/640	29/7206	1.28195646223e-12
ko03022	Basal transcription factors	22/640	44/7206	1.67934678269e-12
ko03440	Homologous recombination	21/640	41/7206	2.96387773198e-12
ko03410	Base excision repair	20/640	38/7206	5.09523639358e-12
ko03420	Nucleotide excision repair	22/640	46/7206	5.30491198305e-12
ko03015	mRNA surveillance pathway	31/640	93/7206	2.80371698127e-11
ko04144	Endocytosis	3/640	342/7206	8.08909318039e-11
ko04020	Calcium signaling pathway	1/640	265/7206	7.21504336553e-10
ko03018	RNA degradation	27/640	84/7206	1.37098879534e-09
ko04024	cAMP signaling pathway	3/640	279/7206	2.10690667647e-08
ko04360	Axon guidance	3/640	233/7206	1.00813594497e-06
ko04932	Non-alcoholic fatty liver disease (NAFLD)	1/640	182/7206	1.07420782491e-06
ko04921	Oxytocin signaling pathway	2/640	209/7206	1.43256283985e-06
ko04151	PI3K-Akt signaling pathway	11/640	390/7206	1.44092831044e-06
ko04022	cGMP-PKG signaling pathway	3/640	216/7206	4.57878069729e-06
ko05322	Systemic lupus erythematosus	31/640	151/7206	7.41022028186e-06
ko04725	Cholinergic synapse	1/640	160/7206	7.96639252654e-06
ko04145	Phagosome	1/640	162/7206	8.1723932791e-06
ko05012	Parkinson's disease	1/640	155/7206	1.18860256421e-05
ko00230	Purine metabolism	36/640	194/7206	1.62161446646e-05
ko04142	Lysosome	1/640	151/7206	1.7666175603e-05
ko04724	Glutamatergic synapse	1/640	152/7206	1.7765715352e-05
ko04072	Phospholipase D signaling pathway	3/640	197/7206	2.04244930166e-05
ko04723	Retrograde endocannabinoid signaling	2/640	175/7206	2.04911492387e-05
ko04015	Rap1 signaling pathway	7/640	278/7206	2.14665758492e-05
ko04510	Focal adhesion	5/640	240/7206	2.35599198103e-05
ko04114	Oocyte meiosis	28/640	139/7206	2.91792275043e-05
ko04726	Serotonergic synapse	1/640	137/7206	5.81134244234e-05
ko04062	Chemokine signaling pathway	4/640	201/7206	7.8446483868e-05
ko04380	Osteoclast differentiation	1/640	134/7206	8.64045878429e-05
ko04014	Ras signaling pathway	8/640	279/7206	8.96574054687e-05
ko04713	Circadian entrainment	1/640	136/7206	9.02474182848e-05
ko04621	NOD-like receptor signaling pathway	2/640	157/7206	9.39701718545e-05
ko04120	Ubiquitin mediated proteolysis	27/640	138/7206	9.8582360224e-05
ko05205	Proteoglycans in cancer	8/640	271/7206	0.000119343543671
ko04371	Apelin signaling pathway	3/640	177/7206	0.000132372484882
ko04270	Vascular smooth muscle contraction	2/640	154/7206	0.00014021280489
ko05145	Toxoplasmosis	1/640	126/7206	0.00019249808585
ko04530	Tight junction	6/640	228/7206	0.000204645028385
ko05152	Tuberculosis	4/640	187/7206	0.000225854995497
ko04810	Regulation of actin cytoskeleton	8/640	264/7206	0.000230838128869
ko04261	Adrenergic signaling in cardiomyocytes	5/640	205/7206	0.000258966202854
ko04668	TNF signaling pathway	1/640	120/7206	0.00027956738117
ko04912	GnRH signaling pathway	1/640	122/7206	0.000288003075963
ko04914	Progesterone-mediated oocyte maturation	21/640	104/7206	0.000318688933581
ko04071	Sphingolipid signaling pathway	3/640	162/7206	0.000382712109217
ko04140	Autophagy - animal	3/640	164/7206	0.000398728664016
ko05169	Epstein-Barr virus infection	34/640	206/7206	0.00040661855998
ko04911	Insulin secretion	1/640	117/7206	0.000420599854905
ko04972	Pancreatic secretion	1/640	111/7206	0.000610078922119
ko04933	AGE-RAGE signaling pathway in diabetic complications	2/640	135/7206	0.000615907210372
ko05418	Fluid shear stress and atherosclerosis	4/640	173/7206	0.000638800849209
ko04670	Leukocyte transendothelial migration	3/640	151/7206	0.000773564633176
ko04010	MAPK signaling pathway	13/640	321/7206	0.000877923573424
ko04727	GABAergic synapse	1/640	110/7206	0.000971789165121
ko05166	HTLV-I infection	43/640	292/7206	0.00101249200184
ko05203	Viral carcinogenesis	41/640	277/7206	0.00109955211453
ko03450	Non-homologous end-joining	6/640	15/7206	0.00119227026326
ko01200	Carbon metabolism	2/640	128/7206	0.00135206998434
ko04540	Gap junction	2/640	128/7206	0.00135206998434
ko04916	Melanogenesis	3/640	142/7206	0.00156502800752
ko04722	Neurotrophin signaling pathway	4/640	160/7206	0.00177327035303
ko04611	Platelet activation	4/640	163/7206	0.00185083829623
ko04650	Natural killer cell mediated cytotoxicity	1/640	97/7206	0.00194962781443
ko05132	Salmonella infection	1/640	98/7206	0.001956936296
ko00564	Glycerophospholipid metabolism	1/640	99/7206	0.00198448926682
ko04620	Toll-like receptor signaling pathway	1/640	100/7206	0.00203282758945
ko04630	Jak-STAT signaling pathway	3/640	132/7206	0.00314205338875
ko05231	Choline metabolism in cancer	3/640	134/7206	0.0031598131549
ko05168	Herpes simplex infection	28/640	182/7206	0.00344919848908
ko05160	Hepatitis C	4/640	153/7206	0.00355565488793
ko04728	Dopaminergic synapse	6/640	185/7206	0.00367327090271
ko05032	Morphine addiction	2/640	110/7206	0.0038026724148
ko03010	Ribosome	3/640	129/7206	0.00444492789414
ko05142	Chagas disease (American trypanosomiasis)	3/640	130/7206	0.00449273079418
ko04210	Apoptosis	6/640	180/7206	0.00499016343717
ko04660	T cell receptor signaling pathway	3/640	124/7206	0.00624165077664
ko04918	Thyroid hormone synthesis	1/640	86/7206	0.00634405987138
ko05133	Pertussis	1/640	87/7206	0.00652250426932
ko05167	Kaposi's sarcoma-associated herpesvirus infection	7/640	191/7206	0.00656869864581
ko04520	Adherens junction	2/640	103/7206	0.00788116621364
ko04925	Aldosterone synthesis and secretion	2/640	105/7206	0.00821296591712
ko05200	Pathways in cancer	28/640	492/7206	0.00845616614948
ko05162	Measles	3/640	120/7206	0.00880058381054
ko04512	ECM-receptor interaction	1/640	79/7206	0.00901749118106
ko04740	Olfactory transduction	1/640	80/7206	0.0090623643395
ko04931	Insulin resistance	4/640	137/7206	0.0092383256388
ko05034	Alcoholism	33/640	238/7206	0.0101936787796
ko03060	Protein export	6/640	23/7206	0.0130195430519
ko05140	Leishmaniasis	1/640	75/7206	0.0131959508058
ko04923	Regulation of lipolysis in adipocytes	1/640	77/7206	0.013577020511
ko05120	Epithelial cell signaling in Helicobacter pylori infection	2/640	92/7206	0.0158014537666
ko04152	AMPK signaling pathway	6/640	161/7206	0.0165152351872
ko04922	Glucagon signaling pathway	4/640	128/7206	0.0175364979763
ko04910	Insulin signaling pathway	7/640	172/7206	0.0206667129025
ko04146	Peroxisome	2/640	89/7206	0.0226521513211
ko05031	Amphetamine addiction	2/640	91/7206	0.0234870789222
ko04750	Inflammatory mediator regulation of TRP channels	4/640	122/7206	0.0237875412307
ko04659	Th17 cell differentiation	3/640	106/7206	0.0238695839821
ko04141	Protein processing in endoplasmic reticulum	8/640	184/7206	0.0251620174506
ko04623	Cytosolic DNA-sensing pathway	8/640	41/7206	0.0255598981947
ko03320	PPAR signaling pathway	1/640	69/7206	0.0296305639788
ko01230	Biosynthesis of amino acids	2/640	85/7206	0.0323130943934
ko04720	Long-term potentiation	3/640	99/7206	0.0328085065408
ko05202	Transcriptional misregulation in cancer	25/640	188/7206	0.0371095279542
ko00330	Arginine and proline metabolism	1/640	61/7206	0.0406498188784
ko05213	Endometrial cancer	1/640	62/7206	0.0409435782031
ko04622	RIG-I-like receptor signaling pathway	1/640	62/7206	0.0409435782031
ko04139	Mitophagy - yeast	7/640	37/7206	0.0414949172174
ko05110	Vibrio cholerae infection	1/640	63/7206	0.0415538026116
ko05161	Hepatitis B	8/640	173/7206	0.0425880190707
ko04070	Phosphatidylinositol signaling system	4/640	112/7206	0.0438858953744
ko05211	Renal cell carcinoma	3/640	96/7206	0.0453694713248
ko04658	Th1 and Th2 cell differentiation	3/640	96/7206	0.0453694713248
ko05230	Central carbon metabolism in cancer	2/640	81/7206	0.0460276005826
ko04138	Autophagy - yeast	2/640	81/7206	0.0460276005826