ko	pathway	ratio_in_study	ratio_in_pop	p_value
ko03040	Spliceosome	83/856	145/7206	2.36243502285e-40
ko04080	Neuroactive ligand-receptor interaction	1/856	423/7206	1.05189466726e-22
ko03050	Proteasome	36/856	54/7206	2.95034014732e-21
ko03030	DNA replication	28/856	38/7206	1.21511683376e-18
ko04110	Cell cycle	53/856	145/7206	6.73955146155e-15
ko04111	Cell cycle - yeast	39/856	90/7206	4.34653565805e-14
ko03013	RNA transport	56/856	166/7206	6.17728019462e-14
ko04020	Calcium signaling pathway	3/856	265/7206	2.3370678873e-11
ko00240	Pyrimidine metabolism	38/856	110/7206	3.35932499938e-10
ko03008	Ribosome biogenesis in eukaryotes	31/856	79/7206	3.87774543443e-10
ko03015	mRNA surveillance pathway	34/856	93/7206	5.16322404077e-10
ko05169	Epstein-Barr virus infection	56/856	206/7206	1.05597983168e-09
ko03420	Nucleotide excision repair	21/856	46/7206	1.10408790173e-08
ko05010	Alzheimer's disease	3/856	202/7206	5.13877942252e-08
ko03410	Base excision repair	18/856	38/7206	6.15240135194e-08
ko05217	Basal cell carcinoma	25/856	68/7206	9.06801236759e-08
ko03430	Mismatch repair	13/856	22/7206	1.52914026693e-07
ko04113	Meiosis - yeast	25/856	70/7206	1.74897901603e-07
ko05012	Parkinson's disease	2/856	155/7206	1.01010549936e-06
ko04724	Glutamatergic synapse	2/856	152/7206	1.50698390831e-06
ko04723	Retrograde endocannabinoid signaling	4/856	175/7206	4.84599858143e-06
ko03020	RNA polymerase	13/856	29/7206	9.36621195418e-06
ko04144	Endocytosis	17/856	342/7206	1.08655990292e-05
ko03460	Fanconi anemia pathway	18/856	51/7206	1.12931140619e-05
ko04932	Non-alcoholic fatty liver disease (NAFLD)	5/856	182/7206	1.27935832445e-05
ko04390	Hippo signaling pathway	43/856	188/7206	1.7057534516e-05
ko05032	Morphine addiction	1/856	110/7206	2.04886841785e-05
ko04070	Phosphatidylinositol signaling system	1/856	112/7206	2.12643354959e-05
ko04060	Cytokine-cytokine receptor interaction	6/856	191/7206	2.15298182572e-05
ko04062	Chemokine signaling pathway	7/856	201/7206	3.4144281744e-05
ko00230	Purine metabolism	43/856	194/7206	3.93296947545e-05
ko04024	cAMP signaling pathway	13/856	279/7206	4.10659514106e-05
ko00970	Aminoacyl-tRNA biosynthesis	15/856	44/7206	9.60415593057e-05
ko04550	Signaling pathways regulating pluripotency of stem cells	37/856	165/7206	0.000122527464986
ko04727	GABAergic synapse	2/856	110/7206	0.000163110669581
ko05224	Breast cancer	38/856	174/7206	0.00018689898386
ko04330	Notch signaling pathway	18/856	62/7206	0.000209861756557
ko04726	Serotonergic synapse	4/856	137/7206	0.00026654921125
ko04662	B cell receptor signaling pathway	1/856	88/7206	0.000349945412638
ko00562	Inositol phosphate metabolism	1/856	89/7206	0.000364646530716
ko04713	Circadian entrainment	4/856	136/7206	0.000396646477262
ko04725	Cholinergic synapse	6/856	160/7206	0.000464888430854
ko04072	Phospholipase D signaling pathway	9/856	197/7206	0.000495758483844
ko03440	Homologous recombination	13/856	41/7206	0.000621998176848
ko04650	Natural killer cell mediated cytotoxicity	2/856	97/7206	0.000746252394905
ko04971	Gastric acid secretion	2/856	98/7206	0.000756439195653
ko04976	Bile secretion	1/856	80/7206	0.000759012905332
ko00564	Glycerophospholipid metabolism	2/856	99/7206	0.000779711616173
ko04310	Wnt signaling pathway	37/856	181/7206	0.000975134531875
ko04970	Salivary secretion	2/856	95/7206	0.00111460364423
ko04923	Regulation of lipolysis in adipocytes	1/856	77/7206	0.00113267914064
ko04610	Complement and coagulation cascades	1/856	79/7206	0.00120980934992
ko04212	Longevity regulating pathway - worm	21/856	87/7206	0.00121917806691
ko04921	Oxytocin signaling pathway	11/856	209/7206	0.00152917916199
ko05120	Epithelial cell signaling in Helicobacter pylori infection	2/856	92/7206	0.00164418844798
ko04380	Osteoclast differentiation	5/856	134/7206	0.00167881376035
ko04010	MAPK signaling pathway	21/856	321/7206	0.00189134585026
ko05166	HTLV-I infection	52/856	292/7206	0.00224009372976
ko04924	Renin secretion	2/856	86/7206	0.00229594982047
ko04920	Adipocytokine signaling pathway	2/856	89/7206	0.00242718004988
ko03320	PPAR signaling pathway	1/856	69/7206	0.00248970989377
ko04022	cGMP-PKG signaling pathway	12/856	216/7206	0.00257265008415
ko04014	Ras signaling pathway	18/856	279/7206	0.00326016029513
ko05168	Herpes simplex infection	35/856	182/7206	0.0034759230212
ko04260	Cardiac muscle contraction	3/856	98/7206	0.00401370237521
ko05222	Small cell lung cancer	20/856	89/7206	0.00434651715099
ko04912	GnRH signaling pathway	5/856	122/7206	0.00441108186605
ko05231	Choline metabolism in cancer	6/856	134/7206	0.00443080192427
ko04931	Insulin resistance	6/856	137/7206	0.00459494800133
ko05230	Central carbon metabolism in cancer	2/856	81/7206	0.00490326678013
ko04138	Autophagy - yeast	2/856	81/7206	0.00490326678013
ko04712	Circadian rhythm - plant	4/856	7/7206	0.00514688942044
ko00561	Glycerolipid metabolism	1/856	63/7206	0.00544879364025
ko04621	NOD-like receptor signaling pathway	8/856	157/7206	0.00568229562726
ko04925	Aldosterone synthesis and secretion	4/856	105/7206	0.00592476548258
ko04630	Jak-STAT signaling pathway	6/856	132/7206	0.00610245238281
ko00670	One carbon pool by folate	7/856	20/7206	0.0062479787805
ko04371	Apelin signaling pathway	10/856	177/7206	0.00663509807448
ko04068	FoxO signaling pathway	9/856	167/7206	0.00724555035017
ko04340	Hedgehog signaling pathway	14/856	58/7206	0.00737138086633
ko01212	Fatty acid metabolism	1/856	60/7206	0.0080832586791
ko01200	Carbon metabolism	6/856	128/7206	0.00826263960331
ko04911	Insulin secretion	5/856	117/7206	0.00864146080942
ko04142	Lysosome	8/856	151/7206	0.0102995558912
ko03018	RNA degradation	18/856	84/7206	0.0104427342305
ko04066	HIF-1 signaling pathway	6/856	123/7206	0.0111419046767
ko05414	Dilated cardiomyopathy	5/856	112/7206	0.011530687607
ko04120	Ubiquitin mediated proteolysis	26/856	138/7206	0.0159853303021
ko04950	Maturity onset diabetes of the young	8/856	29/7206	0.0168189408809
ko04922	Glucagon signaling pathway	7/856	128/7206	0.0190109542042
ko00514	Other types of O-glycan biosynthesis	8/856	30/7206	0.0206165869556
ko05130	Pathogenic Escherichia coli infection	16/856	77/7206	0.02087369525
ko04612	Antigen processing and presentation	16/856	77/7206	0.02087369525
ko05205	Proteoglycans in cancer	45/856	271/7206	0.021063893699
ko04730	Long-term depression	3/856	78/7206	0.0216986382589
ko04659	Th17 cell differentiation	5/856	106/7206	0.0218064029947
ko00380	Tryptophan metabolism	1/856	50/7206	0.0259186177224
ko05410	Hypertrophic cardiomyopathy (HCM)	5/856	100/7206	0.0287299658858
ko04620	Toll-like receptor signaling pathway	5/856	100/7206	0.0287299658858
ko00600	Sphingolipid metabolism	2/856	63/7206	0.0294643164002
ko04917	Prolactin signaling pathway	4/856	87/7206	0.0299124129148
ko05140	Leishmaniasis	3/856	75/7206	0.030311648204
ko04146	Peroxisome	4/856	89/7206	0.0303558788985
ko04933	AGE-RAGE signaling pathway in diabetic complications	8/856	135/7206	0.0306809024524
ko04370	VEGF signaling pathway	3/856	77/7206	0.0312117027791
ko04217	Necroptosis	12/856	178/7206	0.0337999283514
ko04972	Pancreatic secretion	6/856	111/7206	0.0367874162657
ko04261	Adrenergic signaling in cardiomyocytes	15/856	205/7206	0.0375922319822
ko00071	Fatty acid degradation	1/856	45/7206	0.0376418106623
ko04728	Dopaminergic synapse	13/856	185/7206	0.0378620638307
ko05204	Chemical carcinogenesis	1/856	48/7206	0.0395615435922
ko05142	Chagas disease (American trypanosomiasis)	8/856	130/7206	0.0398252520229
ko04915	Estrogen signaling pathway	8/856	131/7206	0.0399667903387
ko04961	Endocrine and other factor-regulated calcium reabsorption	2/856	59/7206	0.041640616229
ko04910	Insulin signaling pathway	12/856	172/7206	0.0424838182333
ko05030	Cocaine addiction	3/856	73/7206	0.0429333762039
ko04742	Taste transduction	2/856	61/7206	0.0433174896743
ko05206	MicroRNAs in cancer	30/856	177/7206	0.0444681600721
ko04350	TGF-beta signaling pathway	19/856	103/7206	0.0453487724212
ko03060	Protein export	6/856	23/7206	0.0473066025267