ko	pathway	ratio_in_study	ratio_in_pop	p_value
ko05033	Nicotine addiction	33/617	56/7206	1.2790661814e-21
ko04721	Synaptic vesicle cycle	39/617	80/7206	2.77383629573e-21
ko04724	Glutamatergic synapse	52/617	152/7206	2.15730031673e-19
ko04728	Dopaminergic synapse	56/617	185/7206	5.49544299014e-18
ko04727	GABAergic synapse	39/617	110/7206	2.0529772536e-15
ko05032	Morphine addiction	39/617	110/7206	2.0529772536e-15
ko04723	Retrograde endocannabinoid signaling	49/617	175/7206	2.24123530445e-14
ko04713	Circadian entrainment	42/617	136/7206	4.30169381579e-14
ko04080	Neuroactive ligand-receptor interaction	84/617	423/7206	5.58816362034e-14
ko04726	Serotonergic synapse	34/617	137/7206	7.66048342528e-09
ko04024	cAMP signaling pathway	54/617	279/7206	9.25800358253e-09
ko04725	Cholinergic synapse	37/617	160/7206	1.3104995974e-08
ko05031	Amphetamine addiction	26/617	91/7206	2.05585890213e-08
ko05030	Cocaine addiction	22/617	73/7206	8.90596786015e-08
ko04911	Insulin secretion	28/617	117/7206	3.7170119526e-07
ko05014	Amyotrophic lateral sclerosis (ALS)	21/617	74/7206	5.40493431306e-07
ko04514	Cell adhesion molecules (CAMs)	29/617	130/7206	1.11393996767e-06
ko04060	Cytokine-cytokine receptor interaction	1/617	191/7206	1.13281716348e-06
ko04261	Adrenergic signaling in cardiomyocytes	39/617	205/7206	1.47488207989e-06
ko04720	Long-term potentiation	24/617	99/7206	1.98643929895e-06
ko04744	Phototransduction	13/617	36/7206	4.25715659923e-06
ko04010	MAPK signaling pathway	50/617	321/7206	2.34480800683e-05
ko04970	Salivary secretion	20/617	95/7206	0.000122394763704
ko04966	Collecting duct acid secretion	9/617	26/7206	0.000192615213429
ko04961	Endocrine and other factor-regulated calcium reabsorption	14/617	59/7206	0.000346657625264
ko03040	Spliceosome	2/617	145/7206	0.000434244106112
ko04360	Axon guidance	36/617	233/7206	0.000467693980275
ko04120	Ubiquitin mediated proteolysis	2/617	138/7206	0.000620063564417
ko00604	Glycosphingolipid biosynthesis - ganglio series	6/617	14/7206	0.000634637924583
ko04921	Oxytocin signaling pathway	32/617	209/7206	0.00100887506466
ko04742	Taste transduction	13/617	61/7206	0.00163706339787
ko04022	cGMP-PKG signaling pathway	32/617	216/7206	0.00186150279446
ko01200	Carbon metabolism	2/617	128/7206	0.00197687431605
ko04350	TGF-beta signaling pathway	1/617	103/7206	0.00202808091622
ko05110	Vibrio cholerae infection	13/617	63/7206	0.00222675550906
ko05162	Measles	2/617	120/7206	0.00268603014522
ko04932	Non-alcoholic fatty liver disease (NAFLD)	5/617	182/7206	0.00276325160114
ko05034	Alcoholism	34/617	238/7206	0.00293102653514
ko04972	Pancreatic secretion	19/617	111/7206	0.00307339094254
ko04730	Long-term depression	15/617	78/7206	0.00310578220056
ko05322	Systemic lupus erythematosus	4/617	151/7206	0.00485747135219
ko05205	Proteoglycans in cancer	11/617	271/7206	0.00531417068328
ko04014	Ras signaling pathway	37/617	279/7206	0.0062419750773
ko04146	Peroxisome	1/617	89/7206	0.00639651740329
ko00533	Glycosaminoglycan biosynthesis - keratan sulfate	5/617	15/7206	0.00658027435591
ko04145	Phagosome	24/617	162/7206	0.00670158207261
ko05168	Herpes simplex infection	6/617	182/7206	0.00684253199493
ko04141	Protein processing in endoplasmic reticulum	6/617	184/7206	0.00696869318317
ko03013	RNA transport	5/617	166/7206	0.00699436526937
ko05120	Epithelial cell signaling in Helicobacter pylori infection	16/617	92/7206	0.00705728033923
ko05164	Influenza A	5/617	167/7206	0.00709983153303
ko05203	Viral carcinogenesis	12/617	277/7206	0.00821611877993
ko04066	HIF-1 signaling pathway	3/617	123/7206	0.00883522805505
ko04964	Proximal tubule bicarbonate reclamation	7/617	29/7206	0.00959715074545
ko04510	Focal adhesion	10/617	240/7206	0.00967925338106
ko04924	Renin secretion	15/617	86/7206	0.00978976407114
ko04915	Estrogen signaling pathway	20/617	131/7206	0.0105616714419
ko04621	NOD-like receptor signaling pathway	5/617	157/7206	0.0131213794897
ko04962	Vasopressin-regulated water reabsorption	11/617	58/7206	0.0146210278936
ko04064	NF-kappa B signaling pathway	2/617	96/7206	0.0159807943713
ko05146	Amoebiasis	2/617	99/7206	0.0166616328871
ko00310	Lysine degradation	1/617	73/7206	0.0194257757683
ko04114	Oocyte meiosis	20/617	139/7206	0.0203178622823
ko04020	Calcium signaling pathway	33/617	265/7206	0.0251385498692
ko00603	Glycosphingolipid biosynthesis - globo and isoglobo series	3/617	8/7206	0.0252291674401
ko04260	Cardiac muscle contraction	15/617	98/7206	0.0266120575939
ko04071	Sphingolipid signaling pathway	22/617	162/7206	0.0314881276363
ko04950	Maturity onset diabetes of the young	6/617	29/7206	0.0333302746182
ko04391	Hippo signaling pathway - fly	14/617	90/7206	0.0337745845836
ko04540	Gap junction	18/617	128/7206	0.0361279616554
ko00561	Glycerolipid metabolism	1/617	63/7206	0.0409400033861
ko05412	Arrhythmogenic right ventricular cardiomyopathy (ARVC)	12/617	79/7206	0.0422701042835
ko04740	Olfactory transduction	12/617	80/7206	0.0448857103398
ko03018	RNA degradation	2/617	84/7206	0.0463443728007
ko04611	Platelet activation	7/617	163/7206	0.0470814911189
ko04140	Autophagy - animal	7/617	164/7206	0.0471778289731
ko05167	Kaposi's sarcoma-associated herpesvirus infection	24/617	191/7206	0.0493926464642