ko	pathway	ratio_in_study	ratio_in_pop	p_value
ko04060	Cytokine-cytokine receptor interaction	58/509	191/7206	7.44293634757e-23
ko04380	Osteoclast differentiation	36/509	134/7206	9.38384294639e-13
ko05164	Influenza A	39/509	167/7206	1.24556790551e-11
ko05340	Primary immunodeficiency	16/509	30/7206	1.7599922162e-11
ko04621	NOD-like receptor signaling pathway	37/509	157/7206	3.21333478253e-11
ko04064	NF-kappa B signaling pathway	27/509	96/7206	2.27964445915e-10
ko04650	Natural killer cell mediated cytotoxicity	27/509	97/7206	2.95401635968e-10
ko05162	Measles	30/509	120/7206	5.39327837129e-10
ko05140	Leishmaniasis	23/509	75/7206	7.67709506691e-10
ko05145	Toxoplasmosis	30/509	126/7206	1.91608853287e-09
ko05321	Inflammatory bowel disease (IBD)	19/509	56/7206	3.52533434192e-09
ko05150	Staphylococcus aureus infection	15/509	36/7206	6.17659958328e-09
ko04659	Th17 cell differentiation	26/509	106/7206	1.20766538301e-08
ko04620	Toll-like receptor signaling pathway	25/509	100/7206	1.52925324096e-08
ko05330	Allograft rejection	12/509	24/7206	1.67765005932e-08
ko04217	Necroptosis	35/509	178/7206	1.90708146402e-08
ko05320	Autoimmune thyroid disease	13/509	29/7206	2.22624940372e-08
ko05168	Herpes simplex infection	35/509	182/7206	3.45439595955e-08
ko05152	Tuberculosis	35/509	187/7206	7.05008181253e-08
ko04630	Jak-STAT signaling pathway	28/509	132/7206	9.81016448379e-08
ko04640	Hematopoietic cell lineage	18/509	64/7206	2.41043658743e-07
ko04658	Th1 and Th2 cell differentiation	22/509	96/7206	5.82982677581e-07
ko04672	Intestinal immune network for IgA production	13/509	37/7206	6.90152973546e-07
ko04612	Antigen processing and presentation	19/509	77/7206	1.03810689698e-06
ko05332	Graft-versus-host disease	9/509	18/7206	1.11565647286e-06
ko04660	T cell receptor signaling pathway	25/509	124/7206	1.31352053865e-06
ko05133	Pertussis	20/509	87/7206	1.80760812946e-06
ko04610	Complement and coagulation cascades	18/509	79/7206	6.79144194926e-06
ko05310	Asthma	8/509	17/7206	8.0680420829e-06
ko05144	Malaria	13/509	45/7206	8.36339423299e-06
ko05167	Kaposi's sarcoma-associated herpesvirus infection	31/509	191/7206	9.96707671488e-06
ko04622	RIG-I-like receptor signaling pathway	15/509	62/7206	1.8483086237e-05
ko04062	Chemokine signaling pathway	31/509	201/7206	3.18568364694e-05
ko00120	Primary bile acid biosynthesis	8/509	20/7206	3.45683790239e-05
ko05323	Rheumatoid arthritis	18/509	89/7206	3.8504989035e-05
ko00590	Arachidonic acid metabolism	13/509	52/7206	4.59905976628e-05
ko04623	Cytosolic DNA-sensing pathway	11/509	41/7206	8.82901913364e-05
ko04662	B cell receptor signaling pathway	17/509	88/7206	0.000115009729086
ko00592	alpha-Linolenic acid metabolism	7/509	19/7206	0.000200647749685
ko05161	Hepatitis B	26/509	173/7206	0.000220054444049
ko05034	Alcoholism	4/509	238/7206	0.000251147768448
ko04940	Type I diabetes mellitus	9/509	32/7206	0.000262948288997
ko05142	Chagas disease (American trypanosomiasis)	21/509	130/7206	0.000341792484971
ko03040	Spliceosome	1/509	145/7206	0.000455848960255
ko04916	Melanogenesis	1/509	142/7206	0.000692156180542
ko04728	Dopaminergic synapse	3/509	185/7206	0.00119529038138
ko04390	Hippo signaling pathway	3/509	188/7206	0.0012367231449
ko04146	Peroxisome	15/509	89/7206	0.00128702859052
ko03010	Ribosome	1/509	129/7206	0.00145214640397
ko04310	Wnt signaling pathway	3/509	181/7206	0.00171867388959
ko04668	TNF signaling pathway	18/509	120/7206	0.00191948158323
ko04723	Retrograde endocannabinoid signaling	3/509	175/7206	0.0024221149185
ko04210	Apoptosis	24/509	180/7206	0.002701493075
ko04110	Cell cycle	2/509	145/7206	0.00284954705858
ko05160	Hepatitis C	21/509	153/7206	0.00339095522549
ko00950	Isoquinoline alkaloid biosynthesis	4/509	10/7206	0.00366474029909
ko04972	Pancreatic secretion	1/509	111/7206	0.00451855857584
ko05032	Morphine addiction	1/509	110/7206	0.00451954269249
ko00360	Phenylalanine metabolism	5/509	17/7206	0.00523110254596
ko05134	Legionellosis	12/509	74/7206	0.00528214058675
ko04713	Circadian entrainment	2/509	136/7206	0.00594697382326
ko04012	ErbB signaling pathway	1/509	109/7206	0.006922644714
ko00350	Tyrosine metabolism	7/509	33/7206	0.00716919197836
ko03320	PPAR signaling pathway	11/509	69/7206	0.00844805215917
ko05224	Breast cancer	4/509	174/7206	0.00991898518944
ko04145	Phagosome	20/509	162/7206	0.0124549278264
ko04611	Platelet activation	20/509	163/7206	0.0129790307673
ko00982	Drug metabolism - cytochrome P450	7/509	37/7206	0.0135357167106
ko00480	Glutathione metabolism	9/509	55/7206	0.0139931924004
ko04137	Mitophagy - animal	12/509	82/7206	0.0143282838153
ko04911	Insulin secretion	2/509	117/7206	0.0167439576221
ko05204	Chemical carcinogenesis	8/509	48/7206	0.0180162283729
ko04114	Oocyte meiosis	3/509	139/7206	0.0180402025571
ko04666	Fc gamma R-mediated phagocytosis	16/509	122/7206	0.0181981565938
ko04080	Neuroactive ligand-receptor interaction	18/509	423/7206	0.0185289241812
ko00980	Metabolism of xenobiotics by cytochrome P450	7/509	40/7206	0.0204292794462
ko05016	Huntington's disease	7/509	215/7206	0.021539658937
ko05143	African trypanosomiasis	6/509	32/7206	0.0226081236735
ko00140	Steroid hormone biosynthesis	7/509	41/7206	0.0231880478835
ko04727	GABAergic synapse	2/509	110/7206	0.0235336930302
ko04514	Cell adhesion molecules (CAMs)	16/509	130/7206	0.024428492437
ko04724	Glutamatergic synapse	4/509	152/7206	0.0248401064062
ko05132	Salmonella infection	13/509	98/7206	0.0260168152717
ko00960	Tropane, piperidine and pyridine alkaloid biosynthesis	2/509	4/7206	0.0271515145549
ko04925	Aldosterone synthesis and secretion	2/509	105/7206	0.0332288639157
ko05418	Fluid shear stress and atherosclerosis	20/509	173/7206	0.0334896820565
ko04530	Tight junction	8/509	228/7206	0.0343273255873
ko04540	Gap junction	3/509	128/7206	0.0346476870821
ko05166	HTLV-I infection	30/509	292/7206	0.0351808179056
ko00071	Fatty acid degradation	7/509	45/7206	0.0367714697636
ko00400	Phenylalanine, tyrosine and tryptophan biosynthesis	2/509	5/7206	0.0431551751509
ko04721	Synaptic vesicle cycle	1/509	80/7206	0.043898512271
ko05131	Shigellosis	11/509	82/7206	0.0458632297728
ko04971	Gastric acid secretion	2/509	98/7206	0.0464647664183
ko04720	Long-term potentiation	2/509	99/7206	0.0465896758676
ko04912	GnRH signaling pathway	3/509	122/7206	0.0475418934174