ko	pathway	ratio_in_study	ratio_in_pop	p_value
ko04080	Neuroactive ligand-receptor interaction	154/947	423/7206	1.66114501919e-36
ko05033	Nicotine addiction	49/947	56/7206	2.00798741565e-36
ko04724	Glutamatergic synapse	80/947	152/7206	4.43946716927e-32
ko04727	GABAergic synapse	62/947	110/7206	2.99508911873e-27
ko05032	Morphine addiction	62/947	110/7206	2.99508911873e-27
ko04713	Circadian entrainment	62/947	136/7206	8.62849507516e-21
ko04723	Retrograde endocannabinoid signaling	72/947	175/7206	9.14478443394e-21
ko04728	Dopaminergic synapse	74/947	185/7206	1.88844296106e-20
ko04725	Cholinergic synapse	65/947	160/7206	1.68532363093e-18
ko04721	Synaptic vesicle cycle	42/947	80/7206	2.80344681147e-17
ko04744	Phototransduction	27/947	36/7206	3.31686416458e-17
ko04024	cAMP signaling pathway	83/947	279/7206	1.39688447935e-13
ko04742	Taste transduction	31/947	61/7206	1.37401670379e-12
ko04726	Serotonergic synapse	48/947	137/7206	3.4333213603e-11
ko04911	Insulin secretion	43/947	117/7206	6.24818082628e-11
ko04020	Calcium signaling pathway	73/947	265/7206	1.94589800826e-10
ko04921	Oxytocin signaling pathway	62/947	209/7206	2.13021260831e-10
ko04261	Adrenergic signaling in cardiomyocytes	61/947	205/7206	2.90533298992e-10
ko04740	Olfactory transduction	33/947	80/7206	3.24704251304e-10
ko05031	Amphetamine addiction	34/947	91/7206	3.91836931204e-09
ko04720	Long-term potentiation	35/947	99/7206	1.246826432e-08
ko03040	Spliceosome	1/947	145/7206	3.69062696632e-08
ko05030	Cocaine addiction	28/947	73/7206	4.82374202366e-08
ko04060	Cytokine-cytokine receptor interaction	4/947	191/7206	9.42387616965e-08
ko05203	Viral carcinogenesis	12/947	277/7206	1.09111114183e-06
ko04010	MAPK signaling pathway	73/947	321/7206	1.66587338587e-06
ko05014	Amyotrophic lateral sclerosis (ALS)	25/947	74/7206	3.93281803816e-06
ko04925	Aldosterone synthesis and secretion	31/947	105/7206	7.47889536426e-06
ko04970	Salivary secretion	29/947	95/7206	8.22211486698e-06
ko05412	Arrhythmogenic right ventricular cardiomyopathy (ARVC)	25/947	79/7206	1.45778005751e-05
ko04514	Cell adhesion molecules (CAMs)	35/947	130/7206	1.99122522962e-05
ko05164	Influenza A	6/947	167/7206	3.89957646698e-05
ko03013	RNA transport	6/947	166/7206	3.90884035508e-05
ko04730	Long-term depression	24/947	78/7206	5.20757439799e-05
ko04260	Cardiac muscle contraction	28/947	98/7206	5.28566804071e-05
ko04120	Ubiquitin mediated proteolysis	4/947	138/7206	5.83244226704e-05
ko05322	Systemic lupus erythematosus	5/947	151/7206	7.24142866693e-05
ko05168	Herpes simplex infection	8/947	182/7206	0.000128542017154
ko04072	Phospholipase D signaling pathway	45/947	197/7206	0.000153023223841
ko04610	Complement and coagulation cascades	1/947	79/7206	0.000315165104036
ko05205	Proteoglycans in cancer	17/947	271/7206	0.000317348451794
ko04022	cGMP-PKG signaling pathway	47/947	216/7206	0.000444538289949
ko04621	NOD-like receptor signaling pathway	7/947	157/7206	0.000453808051047
ko04745	Phototransduction - fly	13/947	38/7206	0.00072761964922
ko04971	Gastric acid secretion	25/947	98/7206	0.000784225882122
ko04141	Protein processing in endoplasmic reticulum	10/947	184/7206	0.000830891959019
ko04966	Collecting duct acid secretion	10/947	26/7206	0.00106180024976
ko04972	Pancreatic secretion	27/947	111/7206	0.00153002328605
ko05162	Measles	5/947	120/7206	0.00154412930983
ko04110	Cell cycle	7/947	145/7206	0.00167399961978
ko03008	Ribosome biogenesis in eukaryotes	2/947	79/7206	0.00216483788109
ko04640	Hematopoietic cell lineage	1/947	64/7206	0.00235853386023
ko05166	HTLV-I infection	22/947	292/7206	0.00257517676414
ko05414	Dilated cardiomyopathy	26/947	112/7206	0.00286917043937
ko04070	Phosphatidylinositol signaling system	26/947	112/7206	0.00286917043937
ko05140	Leishmaniasis	2/947	75/7206	0.0031257540203
ko05169	Epstein-Barr virus infection	14/947	206/7206	0.00453225874435
ko04014	Ras signaling pathway	53/947	279/7206	0.00489410754278
ko05016	Huntington's disease	15/947	215/7206	0.00537636676196
ko04064	NF-kappa B signaling pathway	4/947	96/7206	0.00564287079795
ko05161	Hepatitis B	11/947	173/7206	0.00590488788909
ko00604	Glycosphingolipid biosynthesis - ganglio series	6/947	14/7206	0.00595321625418
ko04360	Axon guidance	45/947	233/7206	0.00744235555243
ko00480	Glutathione metabolism	1/947	55/7206	0.00779697877567
ko04915	Estrogen signaling pathway	28/947	131/7206	0.00842814965158
ko04924	Renin secretion	20/947	86/7206	0.00929197691697
ko04612	Antigen processing and presentation	3/947	77/7206	0.0105105718754
ko04540	Gap junction	27/947	128/7206	0.0114522690338
ko04930	Type II diabetes mellitus	14/947	54/7206	0.0128347475589
ko04630	Jak-STAT signaling pathway	8/947	132/7206	0.0128662685829
ko04932	Non-alcoholic fatty liver disease (NAFLD)	13/947	182/7206	0.0139826104248
ko04657	IL-17 signaling pathway	4/947	87/7206	0.0154031431315
ko05410	Hypertrophic cardiomyopathy (HCM)	22/947	100/7206	0.0157797854211
ko04217	Necroptosis	13/947	178/7206	0.0178606082906
ko05034	Alcoholism	44/947	238/7206	0.0186660043099
ko03018	RNA degradation	4/947	84/7206	0.0213923391368
ko00310	Lysine degradation	3/947	73/7206	0.0216163858479
ko04710	Circadian rhythm	11/947	43/7206	0.0226199276166
ko04371	Apelin signaling pathway	34/947	177/7206	0.0234303598313
ko03022	Basal transcription factors	1/947	44/7206	0.0246735642294
ko00071	Fatty acid degradation	1/947	45/7206	0.0248255564697
ko04510	Focal adhesion	20/947	240/7206	0.0249490693396
ko03420	Nucleotide excision repair	1/947	46/7206	0.0254639428319
ko00562	Inositol phosphate metabolism	19/947	89/7206	0.0267253548421
ko05321	Inflammatory bowel disease (IBD)	2/947	56/7206	0.0281321020252
ko04142	Lysosome	11/947	151/7206	0.0283041764147
ko03320	PPAR signaling pathway	3/947	69/7206	0.0296707363765
ko00240	Pyrimidine metabolism	7/947	110/7206	0.0322342324807
ko04062	Chemokine signaling pathway	37/947	201/7206	0.0333928713096
ko00140	Steroid hormone biosynthesis	1/947	41/7206	0.0363221581414
ko05133	Pertussis	5/947	87/7206	0.0374544123092
ko04146	Peroxisome	5/947	89/7206	0.0382314626778
ko00280	Valine, leucine and isoleucine degradation	2/947	54/7206	0.0406614614349
ko04750	Inflammatory mediator regulation of TRP channels	24/947	122/7206	0.0412982259316
ko05145	Toxoplasmosis	9/947	126/7206	0.0452678315113
ko04071	Sphingolipid signaling pathway	30/947	162/7206	0.0453948247574
ko04964	Proximal tubule bicarbonate reclamation	8/947	29/7206	0.0460193945311
ko04140	Autophagy - animal	13/947	164/7206	0.0463710967114
ko04658	Th1 and Th2 cell differentiation	6/947	96/7206	0.0467180012972