ko	pathway	ratio_in_study	ratio_in_pop	p_value
ko04080	Neuroactive ligand-receptor interaction	162/898	423/7206	5.56116982347e-45
ko05033	Nicotine addiction	42/898	56/7206	4.4914729923e-27
ko04724	Glutamatergic synapse	70/898	152/7206	4.49614239917e-25
ko04721	Synaptic vesicle cycle	45/898	80/7206	5.63816660966e-21
ko05032	Morphine addiction	53/898	110/7206	2.35992292287e-20
ko04713	Circadian entrainment	57/898	136/7206	3.37689722224e-18
ko04727	GABAergic synapse	50/898	110/7206	6.62009516291e-18
ko04728	Dopaminergic synapse	68/898	185/7206	8.01400933396e-18
ko04725	Cholinergic synapse	59/898	160/7206	1.11229377384e-15
ko04723	Retrograde endocannabinoid signaling	60/898	175/7206	2.98064111572e-14
ko04024	cAMP signaling pathway	79/898	279/7206	3.79298955018e-13
ko04020	Calcium signaling pathway	75/898	265/7206	1.6693989958e-12
ko04921	Oxytocin signaling pathway	63/898	209/7206	5.51715518134e-12
ko04911	Insulin secretion	42/898	117/7206	4.46216907922e-11
ko04726	Serotonergic synapse	46/898	137/7206	7.41165916443e-11
ko04261	Adrenergic signaling in cardiomyocytes	58/898	205/7206	6.05346725734e-10
ko04742	Taste transduction	27/898	61/7206	6.21319642496e-10
ko05031	Amphetamine addiction	34/898	91/7206	9.55243323516e-10
ko04970	Salivary secretion	33/898	95/7206	1.42363903961e-08
ko04966	Collecting duct acid secretion	15/898	26/7206	4.94267820533e-08
ko05203	Viral carcinogenesis	9/898	277/7206	7.79894105497e-08
ko03040	Spliceosome	1/898	145/7206	1.4388180653e-07
ko04720	Long-term potentiation	31/898	99/7206	5.63016263621e-07
ko05014	Amyotrophic lateral sclerosis (ALS)	25/898	74/7206	1.46971698448e-06
ko04744	Phototransduction	16/898	36/7206	1.90667330024e-06
ko04120	Ubiquitin mediated proteolysis	2/898	138/7206	3.11904864723e-06
ko04360	Axon guidance	54/898	233/7206	4.06089751595e-06
ko05030	Cocaine addiction	24/898	73/7206	4.10890426523e-06
ko05164	Influenza A	4/898	167/7206	4.57468848535e-06
ko04022	cGMP-PKG signaling pathway	51/898	216/7206	4.69814588836e-06
ko05322	Systemic lupus erythematosus	3/898	151/7206	4.82649152819e-06
ko04514	Cell adhesion molecules (CAMs)	35/898	130/7206	5.97944702117e-06
ko05168	Herpes simplex infection	5/898	182/7206	6.08798562906e-06
ko04010	MAPK signaling pathway	68/898	321/7206	8.2794360899e-06
ko04924	Renin secretion	26/898	86/7206	9.39032694668e-06
ko04971	Gastric acid secretion	28/898	98/7206	1.61405400916e-05
ko03013	RNA transport	5/898	166/7206	2.49783900198e-05
ko04972	Pancreatic secretion	30/898	111/7206	2.91822740442e-05
ko04060	Cytokine-cytokine receptor interaction	7/898	191/7206	3.25831458521e-05
ko05205	Proteoglycans in cancer	14/898	271/7206	7.01441778301e-05
ko04621	NOD-like receptor signaling pathway	5/898	157/7206	7.26075223546e-05
ko05110	Vibrio cholerae infection	19/898	63/7206	0.000152992267013
ko04730	Long-term depression	22/898	78/7206	0.000172063557494
ko05412	Arrhythmogenic right ventricular cardiomyopathy (ARVC)	22/898	79/7206	0.000200707797027
ko05162	Measles	3/898	120/7206	0.000216458651039
ko04740	Olfactory transduction	22/898	80/7206	0.000236106930972
ko04925	Aldosterone synthesis and secretion	27/898	105/7206	0.000248836266285
ko04141	Protein processing in endoplasmic reticulum	8/898	184/7206	0.000253649683635
ko04610	Complement and coagulation cascades	1/898	79/7206	0.000491357864492
ko03008	Ribosome biogenesis in eukaryotes	1/898	79/7206	0.000491357864492
ko05161	Hepatitis B	8/898	173/7206	0.000655470868779
ko04612	Antigen processing and presentation	1/898	77/7206	0.000738975471835
ko04014	Ras signaling pathway	54/898	279/7206	0.000807873629935
ko05169	Epstein-Barr virus infection	11/898	206/7206	0.000830444544844
ko05166	HTLV-I infection	19/898	292/7206	0.00105232311514
ko04745	Phototransduction - fly	12/898	38/7206	0.00159324594178
ko04964	Proximal tubule bicarbonate reclamation	10/898	29/7206	0.00184629878353
ko00240	Pyrimidine metabolism	4/898	110/7206	0.00209567379985
ko04540	Gap junction	28/898	128/7206	0.00262177087554
ko04064	NF-kappa B signaling pathway	3/898	96/7206	0.00269236617984
ko04260	Cardiac muscle contraction	23/898	98/7206	0.00287167648438
ko04110	Cell cycle	7/898	145/7206	0.00316401705283
ko04070	Phosphatidylinositol signaling system	25/898	112/7206	0.00342392363869
ko05414	Dilated cardiomyopathy	25/898	112/7206	0.00342392363869
ko04140	Autophagy - animal	9/898	164/7206	0.00391864160887
ko04626	Plant-pathogen interaction	7/898	18/7206	0.00417777225151
ko00604	Glycosphingolipid biosynthesis - ganglio series	6/898	14/7206	0.00455203626276
ko00330	Arginine and proline metabolism	1/898	61/7206	0.00538619532188
ko04146	Peroxisome	3/898	89/7206	0.00542420238703
ko04976	Bile secretion	19/898	80/7206	0.00542557439276
ko05120	Epithelial cell signaling in Helicobacter pylori infection	21/898	92/7206	0.0059870185229
ko05016	Huntington's disease	14/898	215/7206	0.00609017660056
ko04214	Apoptosis - fly	2/898	72/7206	0.00677072081904
ko05140	Leishmaniasis	2/898	75/7206	0.00715003393376
ko05215	Prostate cancer	5/898	111/7206	0.00834102563106
ko05410	Hypertrophic cardiomyopathy (HCM)	22/898	100/7206	0.00853009421579
ko00280	Valine, leucine and isoleucine degradation	1/898	54/7206	0.0116727729752
ko00480	Glutathione metabolism	1/898	55/7206	0.0119621509576
ko04932	Non-alcoholic fatty liver disease (NAFLD)	12/898	182/7206	0.0121817170683
ko05323	Rheumatoid arthritis	19/898	89/7206	0.0150845248552
ko04371	Apelin signaling pathway	33/898	177/7206	0.0152693641472
ko04915	Estrogen signaling pathway	26/898	131/7206	0.0153615292575
ko04217	Necroptosis	12/898	178/7206	0.0157315962113
ko00590	Arachidonic acid metabolism	1/898	52/7206	0.0178105385096
ko04330	Notch signaling pathway	2/898	62/7206	0.0201005722375
ko04640	Hematopoietic cell lineage	2/898	64/7206	0.0205128532573
ko04115	p53 signaling pathway	3/898	74/7206	0.0213289358175
ko01524	Platinum drug resistance	3/898	76/7206	0.0216005498463
ko04145	Phagosome	30/898	162/7206	0.0221499301891
ko04630	Jak-STAT signaling pathway	8/898	132/7206	0.0229665936955
ko04668	TNF signaling pathway	7/898	120/7206	0.0248860744665
ko04750	Inflammatory mediator regulation of TRP channels	24/898	122/7206	0.0255994095202
ko04510	Focal adhesion	19/898	240/7206	0.02853215948
ko05220	Chronic myeloid leukemia	4/898	85/7206	0.0299403440792
ko00310	Lysine degradation	3/898	73/7206	0.0304119279598
ko03022	Basal transcription factors	1/898	44/7206	0.0371884444707
ko05206	MicroRNAs in cancer	13/898	177/7206	0.0374247667573
ko05144	Malaria	1/898	45/7206	0.0379563514753
ko00071	Fatty acid degradation	1/898	45/7206	0.0379563514753
ko03420	Nucleotide excision repair	1/898	46/7206	0.0393354372364
ko05321	Inflammatory bowel disease (IBD)	2/898	56/7206	0.0409314932461
ko04961	Endocrine and other factor-regulated calcium reabsorption	13/898	59/7206	0.0440129963978
ko04072	Phospholipase D signaling pathway	34/898	197/7206	0.0480754980684