ko pathway ratio_in_study ratio_in_pop p_value ko04060 Cytokine-cytokine receptor interaction 33/559 191/7206 1.17080099795e-05 ko00120 Primary bile acid biosynthesis 8/559 20/7206 6.79706276325e-05 ko04710 Circadian rhythm 12/559 43/7206 6.92815068715e-05 ko04380 Osteoclast differentiation 24/559 134/7206 0.000100866531134 ko04137 Mitophagy - animal 17/559 82/7206 0.000145097531935 ko04610 Complement and coagulation cascades 16/559 79/7206 0.000300048467647 ko04070 Phosphatidylinositol signaling system 20/559 112/7206 0.000442464188369 ko03010 Ribosome 1/559 129/7206 0.000663491015493 ko03040 Spliceosome 2/559 145/7206 0.00137846472007 ko04650 Natural killer cell mediated cytotoxicity 17/559 97/7206 0.00151062582658 ko03013 RNA transport 3/559 166/7206 0.00170493180464 ko05145 Toxoplasmosis 20/559 126/7206 0.00196721257199 ko03320 PPAR signaling pathway 13/559 69/7206 0.00217051910213 ko04922 Glucagon signaling pathway 20/559 128/7206 0.00224587512267 ko00592 alpha-Linolenic acid metabolism 6/559 19/7206 0.00239834550127 ko04020 Calcium signaling pathway 34/559 265/7206 0.00320462432792 ko05152 Tuberculosis 26/559 187/7206 0.00324529575111 ko04921 Oxytocin signaling pathway 28/559 209/7206 0.00369322945902 ko05203 Viral carcinogenesis 10/559 277/7206 0.00575575653214 ko04672 Intestinal immune network for IgA production 8/559 37/7206 0.00643094006329 ko05034 Alcoholism 8/559 238/7206 0.0064976156825 ko04270 Vascular smooth muscle contraction 21/559 154/7206 0.00931762024115 ko05321 Inflammatory bowel disease (IBD) 10/559 56/7206 0.0100155974287 ko00140 Steroid hormone biosynthesis 8/559 41/7206 0.0121106601004 ko04022 cGMP-PKG signaling pathway 27/559 216/7206 0.0133055665134 ko00051 Fructose and mannose metabolism 8/559 42/7206 0.0139756062055 ko04621 NOD-like receptor signaling pathway 21/559 157/7206 0.0144430860236 ko04110 Cell cycle 4/559 145/7206 0.0179319181799 ko05150 Staphylococcus aureus infection 7/559 36/7206 0.0188159262284 ko04630 Jak-STAT signaling pathway 18/559 132/7206 0.0195782416659 ko04611 Platelet activation 21/559 163/7206 0.0246386755308 ko00330 Arginine and proline metabolism 10/559 61/7206 0.0250304736791 ko05340 Primary immunodeficiency 6/559 30/7206 0.0253518773042 ko04068 FoxO signaling pathway 21/559 167/7206 0.0267205780073 ko05031 Amphetamine addiction 13/559 91/7206 0.0279585826676 ko04723 Retrograde endocannabinoid signaling 6/559 175/7206 0.0304354470221 ko00350 Tyrosine metabolism 6/559 33/7206 0.0388794788848 ko04066 HIF-1 signaling pathway 16/559 123/7206 0.0390534836727 ko01040 Biosynthesis of unsaturated fatty acids 5/559 25/7206 0.0400487745923 ko04925 Aldosterone synthesis and secretion 14/559 105/7206 0.0411904831247 ko04072 Phospholipase D signaling pathway 23/559 197/7206 0.0425359186774 ko04659 Th17 cell differentiation 14/559 106/7206 0.0429033764165 ko05322 Systemic lupus erythematosus 5/559 151/7206 0.0435060053622 ko04662 B cell receptor signaling pathway 12/559 88/7206 0.0448913141018 ko04626 Plant-pathogen interaction 4/559 18/7206 0.0457735839176 ko04933 AGE-RAGE signaling pathway in diabetic complications 17/559 135/7206 0.0486209229087