ko	pathway	ratio_in_study	ratio_in_pop	p_value
ko04080	Neuroactive ligand-receptor interaction	184/1044	423/7206	6.95856210121e-51
ko04724	Glutamatergic synapse	84/1044	152/7206	1.61613312703e-32
ko05033	Nicotine addiction	47/1044	56/7206	3.03612201829e-31
ko04721	Synaptic vesicle cycle	52/1044	80/7206	3.75988229709e-25
ko04727	GABAergic synapse	62/1044	110/7206	7.34645501144e-25
ko05032	Morphine addiction	61/1044	110/7206	5.81243417921e-24
ko04713	Circadian entrainment	69/1044	136/7206	6.27346285911e-24
ko04728	Dopaminergic synapse	80/1044	185/7206	7.3773865252e-22
ko04725	Cholinergic synapse	71/1044	160/7206	2.7563022767e-20
ko04723	Retrograde endocannabinoid signaling	74/1044	175/7206	1.34032284174e-19
ko04024	cAMP signaling pathway	95/1044	279/7206	4.32090476318e-17
ko04742	Taste transduction	35/1044	61/7206	7.00415132815e-15
ko04911	Insulin secretion	50/1044	117/7206	7.77113534734e-14
ko04020	Calcium signaling pathway	85/1044	265/7206	1.11592825986e-13
ko04726	Serotonergic synapse	54/1044	137/7206	4.29320215252e-13
ko04921	Oxytocin signaling pathway	71/1044	209/7206	6.84311049402e-13
ko04744	Phototransduction	24/1044	36/7206	1.25692075439e-12
ko04261	Adrenergic signaling in cardiomyocytes	67/1044	205/7206	2.34729032502e-11
ko05031	Amphetamine addiction	39/1044	91/7206	4.02279206952e-11
ko04720	Long-term potentiation	41/1044	99/7206	4.72882343807e-11
ko03040	Spliceosome	1/1044	145/7206	5.75182194552e-09
ko05203	Viral carcinogenesis	11/1044	277/7206	9.30234956928e-09
ko04970	Salivary secretion	35/1044	95/7206	4.66418883153e-08
ko05168	Herpes simplex infection	5/1044	182/7206	1.63057552849e-07
ko05164	Influenza A	4/1044	167/7206	1.69483045353e-07
ko04740	Olfactory transduction	30/1044	80/7206	2.71564330186e-07
ko05014	Amyotrophic lateral sclerosis (ALS)	28/1044	74/7206	5.46747632344e-07
ko04060	Cytokine-cytokine receptor interaction	7/1044	191/7206	1.12555612088e-06
ko04971	Gastric acid secretion	33/1044	98/7206	1.43858987798e-06
ko05030	Cocaine addiction	27/1044	73/7206	1.4691509218e-06
ko05412	Arrhythmogenic right ventricular cardiomyopathy (ARVC)	28/1044	79/7206	2.52680837488e-06
ko04966	Collecting duct acid secretion	14/1044	26/7206	2.89273237763e-06
ko04925	Aldosterone synthesis and secretion	34/1044	105/7206	3.5942008819e-06
ko04120	Ubiquitin mediated proteolysis	4/1044	138/7206	7.91536131146e-06
ko05322	Systemic lupus erythematosus	5/1044	151/7206	1.02827392305e-05
ko04360	Axon guidance	58/1044	233/7206	2.51718272462e-05
ko03013	RNA transport	7/1044	166/7206	2.76505298683e-05
ko04022	cGMP-PKG signaling pathway	54/1044	216/7206	3.17891285029e-05
ko04745	Phototransduction - fly	16/1044	38/7206	3.21238385206e-05
ko04260	Cardiac muscle contraction	30/1044	98/7206	3.5062444194e-05
ko05414	Dilated cardiomyopathy	33/1044	112/7206	3.52539294357e-05
ko04070	Phosphatidylinositol signaling system	33/1044	112/7206	3.52539294357e-05
ko04010	MAPK signaling pathway	73/1044	321/7206	4.59531518626e-05
ko05205	Proteoglycans in cancer	18/1044	271/7206	6.61853786117e-05
ko04514	Cell adhesion molecules (CAMs)	36/1044	130/7206	7.41132159969e-05
ko04621	NOD-like receptor signaling pathway	7/1044	157/7206	7.72707629304e-05
ko04924	Renin secretion	26/1044	86/7206	0.000152496467402
ko05161	Hepatitis B	9/1044	173/7206	0.000166291887038
ko04972	Pancreatic secretion	31/1044	111/7206	0.000193689101441
ko04730	Long-term depression	24/1044	78/7206	0.000242115495721
ko05169	Epstein-Barr virus infection	13/1044	206/7206	0.000278286907314
ko04540	Gap junction	34/1044	128/7206	0.00031415305048
ko04141	Protein processing in endoplasmic reticulum	11/1044	184/7206	0.000407957650327
ko04072	Phospholipase D signaling pathway	47/1044	197/7206	0.000423922436441
ko05110	Vibrio cholerae infection	20/1044	63/7206	0.000427500803643
ko03008	Ribosome biogenesis in eukaryotes	2/1044	79/7206	0.000994370870768
ko04110	Cell cycle	8/1044	145/7206	0.00112651911427
ko05140	Leishmaniasis	2/1044	75/7206	0.0013868009782
ko05162	Measles	6/1044	120/7206	0.00149836669658
ko00604	Glycosphingolipid biosynthesis - ganglio series	7/1044	14/7206	0.00177220815322
ko04064	NF-kappa B signaling pathway	4/1044	96/7206	0.00189045639645
ko04976	Bile secretion	22/1044	80/7206	0.00208941524703
ko04626	Plant-pathogen interaction	8/1044	18/7206	0.00213720039178
ko05166	HTLV-I infection	25/1044	292/7206	0.00220925790134
ko04750	Inflammatory mediator regulation of TRP channels	30/1044	122/7206	0.00263994516117
ko00480	Glutathione metabolism	1/1044	55/7206	0.00325428434913
ko04146	Peroxisome	4/1044	89/7206	0.00375725780413
ko04630	Jak-STAT signaling pathway	8/1044	132/7206	0.00377478635086
ko00240	Pyrimidine metabolism	6/1044	110/7206	0.0039356161191
ko04961	Endocrine and other factor-regulated calcium reabsorption	17/1044	59/7206	0.00431804009034
ko00590	Arachidonic acid metabolism	1/1044	52/7206	0.00484582577075
ko04612	Antigen processing and presentation	3/1044	77/7206	0.00497980187426
ko04915	Estrogen signaling pathway	31/1044	131/7206	0.00535612558671
ko05410	Hypertrophic cardiomyopathy (HCM)	25/1044	100/7206	0.00585623231343
ko04640	Hematopoietic cell lineage	2/1044	64/7206	0.00638436693665
ko04140	Autophagy - animal	12/1044	164/7206	0.00672332726683
ko04210	Apoptosis	14/1044	180/7206	0.00720034704474
ko04932	Non-alcoholic fatty liver disease (NAFLD)	14/1044	182/7206	0.00728620155048
ko03018	RNA degradation	4/1044	84/7206	0.00743519244976
ko04014	Ras signaling pathway	56/1044	279/7206	0.00908853788952
ko00330	Arginine and proline metabolism	2/1044	61/7206	0.0092210132637
ko00562	Inositol phosphate metabolism	22/1044	89/7206	0.00937413218784
ko04214	Apoptosis - fly	3/1044	72/7206	0.0103271111535
ko03420	Nucleotide excision repair	1/1044	46/7206	0.0107241151986
ko00260	Glycine, serine and threonine metabolism	1/1044	48/7206	0.0113899190653
ko05219	Bladder cancer	1/1044	48/7206	0.0113899190653
ko04668	TNF signaling pathway	8/1044	120/7206	0.0122889959804
ko05120	Epithelial cell signaling in Helicobacter pylori infection	22/1044	92/7206	0.0159047815451
ko03022	Basal transcription factors	1/1044	44/7206	0.0161371198511
ko05144	Malaria	1/1044	45/7206	0.0167600255146
ko00071	Fatty acid degradation	1/1044	45/7206	0.0167600255146
ko05321	Inflammatory bowel disease (IBD)	2/1044	56/7206	0.0198126279312
ko01524	Platinum drug resistance	4/1044	76/7206	0.0203674570752
ko04923	Regulation of lipolysis in adipocytes	19/1044	77/7206	0.0209378727386
ko04350	TGF-beta signaling pathway	7/1044	103/7206	0.0233595205833
ko00980	Metabolism of xenobiotics by cytochrome P450	1/1044	40/7206	0.0236255891686
ko00140	Steroid hormone biosynthesis	1/1044	41/7206	0.0238441735781
ko05131	Shigellosis	5/1044	82/7206	0.0266041971002
ko00310	Lysine degradation	4/1044	73/7206	0.0281203384814
ko05418	Fluid shear stress and atherosclerosis	15/1044	173/7206	0.0281440475824
ko04622	RIG-I-like receptor signaling pathway	3/1044	62/7206	0.0281879925269
ko04964	Proximal tubule bicarbonate reclamation	9/1044	29/7206	0.0284714374615
ko05215	Prostate cancer	8/1044	111/7206	0.028610272543
ko04620	Toll-like receptor signaling pathway	7/1044	100/7206	0.0310660349245
ko00982	Drug metabolism - cytochrome P450	1/1044	37/7206	0.0349763025673
ko04933	AGE-RAGE signaling pathway in diabetic complications	11/1044	135/7206	0.0351349131092
ko03410	Base excision repair	1/1044	38/7206	0.0351857053478
ko04912	GnRH signaling pathway	26/1044	122/7206	0.0373053531499
ko03320	PPAR signaling pathway	4/1044	69/7206	0.0381807467774
ko04218	Cellular senescence	16/1044	177/7206	0.0392507228719
ko05206	MicroRNAs in cancer	16/1044	177/7206	0.0392507228719
ko05145	Toxoplasmosis	10/1044	126/7206	0.0398009680282
ko00380	Tryptophan metabolism	2/1044	50/7206	0.0403762380441
ko04658	Th1 and Th2 cell differentiation	7/1044	96/7206	0.041032845885
ko04657	IL-17 signaling pathway	6/1044	87/7206	0.0451225083575
ko05133	Pertussis	6/1044	87/7206	0.0451225083575