ko	pathway	ratio_in_study	ratio_in_pop	p_value
ko04610	Complement and coagulation cascades	37/502	79/7206	1.30002866344e-22
ko04974	Protein digestion and absorption	32/502	96/7206	1.63044748848e-14
ko00260	Glycine, serine and threonine metabolism	19/502	48/7206	1.28726325124e-10
ko04975	Fat digestion and absorption	16/502	35/7206	2.86548401524e-10
ko04950	Maturity onset diabetes of the young	14/502	29/7206	1.55659164381e-09
ko01200	Carbon metabolism	28/502	128/7206	3.62306976722e-08
ko04977	Vitamin digestion and absorption	11/502	22/7206	5.87385987785e-08
ko01230	Biosynthesis of amino acids	20/502	85/7206	9.81295058596e-07
ko04976	Bile secretion	19/502	80/7206	1.57582144801e-06
ko04978	Mineral absorption	13/502	40/7206	1.63692972286e-06
ko00010	Glycolysis / Gluconeogenesis	18/502	74/7206	2.04880346597e-06
ko00980	Metabolism of xenobiotics by cytochrome P450	12/502	40/7206	1.0554135662e-05
ko05150	Staphylococcus aureus infection	11/502	36/7206	2.03768058482e-05
ko04310	Wnt signaling pathway	1/502	181/7206	4.43559234291e-05
ko00330	Arginine and proline metabolism	14/502	61/7206	5.6485428487e-05
ko04360	Axon guidance	3/502	233/7206	6.90249267333e-05
ko05034	Alcoholism	3/502	238/7206	7.26835362178e-05
ko05204	Chemical carcinogenesis	12/502	48/7206	7.87247137503e-05
ko00983	Drug metabolism - other enzymes	11/502	42/7206	9.89696390815e-05
ko04062	Chemokine signaling pathway	2/502	201/7206	0.000106369058166
ko04260	Cardiac muscle contraction	18/502	98/7206	0.000120697198011
ko04614	Renin-angiotensin system	7/502	18/7206	0.000123546775332
ko03013	RNA transport	1/502	166/7206	0.000145987887038
ko04144	Endocytosis	8/502	342/7206	0.000180145657446
ko04390	Hippo signaling pathway	2/502	188/7206	0.000221498982014
ko05166	HTLV-I infection	6/502	292/7206	0.000225686257129
ko03320	PPAR signaling pathway	14/502	69/7206	0.00023136782686
ko00620	Pyruvate metabolism	11/502	46/7206	0.000239073400428
ko00040	Pentose and glucuronate interconversions	8/502	26/7206	0.000266870758982
ko04724	Glutamatergic synapse	1/502	152/7206	0.000310971689709
ko05200	Pathways in cancer	16/502	492/7206	0.000325801404122
ko04973	Carbohydrate digestion and absorption	10/502	42/7206	0.000474755367034
ko00500	Starch and sucrose metabolism	9/502	35/7206	0.00049407805384
ko00380	Tryptophan metabolism	11/502	50/7206	0.000519125029913
ko04216	Ferroptosis	10/502	44/7206	0.000705723655238
ko03040	Spliceosome	1/502	145/7206	0.000712602440053
ko04110	Cell cycle	1/502	145/7206	0.000712602440053
ko00630	Glyoxylate and dicarboxylate metabolism	9/502	38/7206	0.000945643956739
ko04120	Ubiquitin mediated proteolysis	1/502	138/7206	0.00101542661938
ko00270	Cysteine and methionine metabolism	10/502	47/7206	0.00121933760408
ko04060	Cytokine-cytokine receptor interaction	3/502	191/7206	0.00125039085415
ko00052	Galactose metabolism	8/502	33/7206	0.00153801116978
ko00680	Methane metabolism	8/502	34/7206	0.00189101752577
ko05169	Epstein-Barr virus infection	4/502	206/7206	0.00194474768506
ko00710	Carbon fixation in photosynthetic organisms	7/502	27/7206	0.00198910549473
ko00051	Fructose and mannose metabolism	9/502	42/7206	0.00201587183203
ko04660	T cell receptor signaling pathway	1/502	124/7206	0.00212246650276
ko00020	Citrate cycle (TCA cycle)	8/502	35/7206	0.00230492551744
ko05206	MicroRNAs in cancer	3/502	177/7206	0.00241951577831
ko00100	Steroid biosynthesis	6/502	21/7206	0.00244096456285
ko04072	Phospholipase D signaling pathway	4/502	197/7206	0.00265873354203
ko04964	Proximal tubule bicarbonate reclamation	7/502	29/7206	0.00309623015491
ko00591	Linoleic acid metabolism	6/502	22/7206	0.00316201779669
ko00053	Ascorbate and aldarate metabolism	6/502	22/7206	0.00316201779669
ko00982	Drug metabolism - cytochrome P450	8/502	37/7206	0.00334349157485
ko05203	Viral carcinogenesis	8/502	277/7206	0.00372933868251
ko00250	Alanine, aspartate and glutamate metabolism	8/502	38/7206	0.00398291760629
ko04922	Glucagon signaling pathway	18/502	128/7206	0.00412030931759
ko00480	Glutathione metabolism	10/502	55/7206	0.00417094478539
ko05410	Hypertrophic cardiomyopathy (HCM)	15/502	100/7206	0.00435448357105
ko04972	Pancreatic secretion	16/502	111/7206	0.00440996483486
ko04013	MAPK signaling pathway - fly	1/502	115/7206	0.00464580712052
ko04140	Autophagy - animal	3/502	164/7206	0.0047522680847
ko04550	Signaling pathways regulating pluripotency of stem cells	3/502	165/7206	0.00478285520749
ko04728	Dopaminergic synapse	4/502	185/7206	0.00511839220235
ko00030	Pentose phosphate pathway	7/502	32/7206	0.00556831293775
ko04933	AGE-RAGE signaling pathway in diabetic complications	2/502	135/7206	0.00583421891259
ko04114	Oocyte meiosis	2/502	139/7206	0.00607797432647
ko00340	Histidine metabolism	6/502	25/7206	0.00627923212221
ko04659	Th17 cell differentiation	1/502	106/7206	0.00661051932387
ko00350	Tyrosine metabolism	7/502	33/7206	0.00665339418299
ko04141	Protein processing in endoplasmic reticulum	4/502	184/7206	0.00739232652661
ko04630	Jak-STAT signaling pathway	2/502	132/7206	0.00848698177944
ko00590	Arachidonic acid metabolism	9/502	52/7206	0.00895201039236
ko05161	Hepatitis B	4/502	173/7206	0.00973567183753
ko04520	Adherens junction	1/502	103/7206	0.00978709695907
ko04350	TGF-beta signaling pathway	1/502	103/7206	0.00978709695907
ko04146	Peroxisome	13/502	89/7206	0.00981005657484
ko04920	Adipocytokine signaling pathway	13/502	89/7206	0.00981005657484
ko00120	Primary bile acid biosynthesis	5/502	20/7206	0.0103831203316
ko04015	Rap1 signaling pathway	9/502	278/7206	0.0109866337936
ko00561	Glycerolipid metabolism	10/502	63/7206	0.0110711982153
ko04014	Ras signaling pathway	9/502	279/7206	0.0110839450575
ko00071	Fatty acid degradation	8/502	45/7206	0.0114442623498
ko00520	Amino sugar and nucleotide sugar metabolism	9/502	55/7206	0.0128618258803
ko04658	Th1 and Th2 cell differentiation	1/502	96/7206	0.0140495669029
ko05132	Salmonella infection	1/502	98/7206	0.0143913411116
ko00521	Streptomycin biosynthesis	3/502	8/7206	0.0144474325057
ko04720	Long-term potentiation	1/502	99/7206	0.0146755972669
ko05162	Measles	2/502	120/7206	0.0170033684811
ko04666	Fc gamma R-mediated phagocytosis	2/502	122/7206	0.0175538537296
ko05168	Herpes simplex infection	5/502	182/7206	0.0179579558226
ko04150	mTOR signaling pathway	5/502	184/7206	0.0180329443149
ko04722	Neurotrophin signaling pathway	4/502	160/7206	0.0182800846027
ko04071	Sphingolipid signaling pathway	4/502	162/7206	0.018318200522
ko04391	Hippo signaling pathway - fly	1/502	90/7206	0.0203593942559
ko00140	Steroid hormone biosynthesis	7/502	41/7206	0.0216639334095
ko04024	cAMP signaling pathway	10/502	279/7206	0.0219428296247
ko00220	Arginine biosynthesis	5/502	24/7206	0.0226238756027
ko00830	Retinol metabolism	7/502	42/7206	0.024491770404
ko04380	Osteoclast differentiation	3/502	134/7206	0.0249034391141
ko04740	Olfactory transduction	11/502	80/7206	0.0250785584424
ko04621	NOD-like receptor signaling pathway	4/502	157/7206	0.0250993160203
ko04713	Circadian entrainment	3/502	136/7206	0.0252423975513
ko00643	Styrene degradation	2/502	4/7206	0.0264448080407
ko00524	Neomycin, kanamycin and gentamicin biosynthesis	2/502	4/7206	0.0264448080407
ko00720	Carbon fixation pathways in prokaryotes	4/502	17/7206	0.0267503855696
ko00360	Phenylalanine metabolism	4/502	17/7206	0.0267503855696
ko05220	Chronic myeloid leukemia	1/502	85/7206	0.0296636140665
ko05210	Colorectal cancer	1/502	86/7206	0.0300160540795
ko05167	Kaposi's sarcoma-associated herpesvirus infection	6/502	191/7206	0.030485305906
ko04657	IL-17 signaling pathway	1/502	87/7206	0.0305122217618
ko04662	B cell receptor signaling pathway	1/502	88/7206	0.0311523696894
ko00410	beta-Alanine metabolism	6/502	35/7206	0.0319576942138
ko04010	MAPK signaling pathway	13/502	321/7206	0.0329002197924
ko01521	EGFR tyrosine kinase inhibitor resistance	2/502	106/7206	0.0332380086898
ko04723	Retrograde endocannabinoid signaling	5/502	175/7206	0.0333821907083
ko04012	ErbB signaling pathway	2/502	109/7206	0.0341241903684
ko04540	Gap junction	3/502	128/7206	0.0343336413682
ko05032	Morphine addiction	2/502	110/7206	0.0346679897821
ko00130	Ubiquinone and other terpenoid-quinone biosynthesis	3/502	11/7206	0.036402985603
ko00472	D-Arginine and D-ornithine metabolism	2/502	5/7206	0.0420597582578
ko00232	Caffeine metabolism	2/502	5/7206	0.0420597582578
ko00400	Phenylalanine, tyrosine and tryptophan biosynthesis	2/502	5/7206	0.0420597582578
ko00311	Penicillin and cephalosporin biosynthesis	2/502	5/7206	0.0420597582578
ko04370	VEGF signaling pathway	1/502	77/7206	0.0424706101623
ko04664	Fc epsilon RI signaling pathway	1/502	77/7206	0.0424706101623
ko04138	Autophagy - yeast	1/502	81/7206	0.0439034338138
ko04620	Toll-like receptor signaling pathway	2/502	100/7206	0.0466153028652
ko04912	GnRH signaling pathway	3/502	122/7206	0.0471459125565
ko01522	Endocrine resistance	3/502	124/7206	0.0477564711605
ko04914	Progesterone-mediated oocyte maturation	2/502	104/7206	0.048499465328