ko	pathway	ratio_in_study	ratio_in_pop	p_value
ko04080	Neuroactive ligand-receptor interaction	188/1202	423/7206	6.46607334206e-44
ko05033	Nicotine addiction	49/1202	56/7206	2.35208749412e-31
ko04724	Glutamatergic synapse	86/1202	152/7206	1.35238897107e-29
ko05032	Morphine addiction	69/1202	110/7206	1.03932906027e-27
ko04727	GABAergic synapse	67/1202	110/7206	7.5348081288e-26
ko04713	Circadian entrainment	74/1202	136/7206	3.7370074819e-24
ko04728	Dopaminergic synapse	85/1202	185/7206	4.15304770057e-21
ko04725	Cholinergic synapse	74/1202	160/7206	1.03241768662e-18
ko04723	Retrograde endocannabinoid signaling	78/1202	175/7206	1.78058168692e-18
ko04024	cAMP signaling pathway	105/1202	279/7206	8.34566495854e-18
ko04721	Synaptic vesicle cycle	43/1202	80/7206	2.79795781926e-14
ko04744	Phototransduction	26/1202	36/7206	2.18275619209e-13
ko04742	Taste transduction	35/1202	61/7206	5.4658745285e-13
ko04020	Calcium signaling pathway	91/1202	265/7206	8.87287660068e-13
ko04360	Axon guidance	82/1202	233/7206	2.90703127998e-12
ko04911	Insulin secretion	50/1202	117/7206	1.91524123473e-11
ko04261	Adrenergic signaling in cardiomyocytes	72/1202	205/7206	1.02864943954e-10
ko03040	Spliceosome	1/1202	145/7206	1.17408591815e-10
ko04921	Oxytocin signaling pathway	72/1202	209/7206	1.97828722018e-10
ko04726	Serotonergic synapse	53/1202	137/7206	4.35988408919e-10
ko05203	Viral carcinogenesis	15/1202	277/7206	1.38260230697e-08
ko03013	RNA transport	5/1202	166/7206	3.68799211956e-08
ko05031	Amphetamine addiction	37/1202	91/7206	4.08129513238e-08
ko05322	Systemic lupus erythematosus	4/1202	151/7206	5.6061047057e-08
ko04720	Long-term potentiation	38/1202	99/7206	1.76579385309e-07
ko04970	Salivary secretion	37/1202	95/7206	1.80110733376e-07
ko04740	Olfactory transduction	32/1202	80/7206	5.23116845161e-07
ko05030	Cocaine addiction	30/1202	73/7206	5.94373005527e-07
ko04010	MAPK signaling pathway	87/1202	321/7206	1.62902108414e-06
ko04022	cGMP-PKG signaling pathway	63/1202	216/7206	4.1518594808e-06
ko04060	Cytokine-cytokine receptor interaction	11/1202	191/7206	7.2932396744e-06
ko04070	Phosphatidylinositol signaling system	38/1202	112/7206	8.18472391938e-06
ko05014	Amyotrophic lateral sclerosis (ALS)	28/1202	74/7206	1.08143637167e-05
ko03008	Ribosome biogenesis in eukaryotes	1/1202	79/7206	1.2797474287e-05
ko04971	Gastric acid secretion	34/1202	98/7206	1.34556691428e-05
ko04925	Aldosterone synthesis and secretion	35/1202	105/7206	2.80024003762e-05
ko04711	Circadian rhythm - fly	9/1202	13/7206	3.65959694092e-05
ko05412	Arrhythmogenic right ventricular cardiomyopathy (ARVC)	28/1202	79/7206	4.76590373333e-05
ko05164	Influenza A	10/1202	167/7206	5.26675392869e-05
ko04972	Pancreatic secretion	35/1202	111/7206	9.28939037597e-05
ko04730	Long-term depression	27/1202	78/7206	9.57533291625e-05
ko04072	Phospholipase D signaling pathway	54/1202	197/7206	0.000134300219842
ko04014	Ras signaling pathway	70/1202	279/7206	0.000286530015345
ko03018	RNA degradation	3/1202	84/7206	0.000325989611837
ko04141	Protein processing in endoplasmic reticulum	14/1202	184/7206	0.000409271560751
ko04260	Cardiac muscle contraction	30/1202	98/7206	0.000544592588583
ko00240	Pyrimidine metabolism	6/1202	110/7206	0.000677021997648
ko05414	Dilated cardiomyopathy	33/1202	112/7206	0.000748681903581
ko04514	Cell adhesion molecules (CAMs)	37/1202	130/7206	0.000761132009185
ko04930	Type II diabetes mellitus	19/1202	54/7206	0.000792263512273
ko00480	Glutathione metabolism	1/1202	55/7206	0.000838288378096
ko05205	Proteoglycans in cancer	26/1202	271/7206	0.000862867000915
ko04612	Antigen processing and presentation	3/1202	77/7206	0.00102036091219
ko04621	NOD-like receptor signaling pathway	12/1202	157/7206	0.00111090895558
ko04640	Hematopoietic cell lineage	2/1202	64/7206	0.0011953752939
ko00590	Arachidonic acid metabolism	1/1202	52/7206	0.00126906066466
ko04710	Circadian rhythm	16/1202	43/7206	0.00134001941858
ko05140	Leishmaniasis	3/1202	75/7206	0.00150675728908
ko04391	Hippo signaling pathway - fly	27/1202	90/7206	0.00151276880457
ko04923	Regulation of lipolysis in adipocytes	24/1202	77/7206	0.0017242730101
ko04110	Cell cycle	11/1202	145/7206	0.00216538565464
ko05168	Herpes simplex infection	16/1202	182/7206	0.00245329659912
ko04146	Peroxisome	5/1202	89/7206	0.00249790895378
ko00330	Arginine and proline metabolism	2/1202	61/7206	0.00271888486035
ko00260	Glycine, serine and threonine metabolism	1/1202	48/7206	0.00290392542074
ko04915	Estrogen signaling pathway	35/1202	131/7206	0.00301126145532
ko04745	Phototransduction - fly	14/1202	38/7206	0.00315054504384
ko04924	Renin secretion	25/1202	86/7206	0.00342263951545
ko04064	NF-kappa B signaling pathway	6/1202	96/7206	0.00352956958498
ko04120	Ubiquitin mediated proteolysis	11/1202	138/7206	0.0037764936702
ko04540	Gap junction	34/1202	128/7206	0.00393306649115
ko00604	Glycosphingolipid biosynthesis - ganglio series	7/1202	14/7206	0.00409042476353
ko05162	Measles	9/1202	120/7206	0.00432402742403
ko05144	Malaria	1/1202	45/7206	0.00434015070823
ko00071	Fatty acid degradation	1/1202	45/7206	0.00434015070823
ko03420	Nucleotide excision repair	1/1202	46/7206	0.00444282643432
ko01200	Carbon metabolism	10/1202	128/7206	0.00551713629161
ko04371	Apelin signaling pathway	44/1202	177/7206	0.00553419337483
ko05169	Epstein-Barr virus infection	20/1202	206/7206	0.00571340504444
ko00562	Inositol phosphate metabolism	25/1202	89/7206	0.00613426873249
ko00534	Glycosaminoglycan biosynthesis - heparan sulfate / heparin	10/1202	26/7206	0.00651394120647
ko04750	Inflammatory mediator regulation of TRP channels	32/1202	122/7206	0.00671156521381
ko03022	Basal transcription factors	1/1202	44/7206	0.00684115835769
ko04961	Endocrine and other factor-regulated calcium reabsorption	18/1202	59/7206	0.00766733172081
ko00980	Metabolism of xenobiotics by cytochrome P450	1/1202	40/7206	0.00979326433952
ko04142	Lysosome	14/1202	151/7206	0.0110257910802
ko00380	Tryptophan metabolism	2/1202	50/7206	0.0120392540544
ko04071	Sphingolipid signaling pathway	39/1202	162/7206	0.0139388342018
ko00982	Drug metabolism - cytochrome P450	1/1202	37/7206	0.0147187937474
ko04976	Bile secretion	22/1202	80/7206	0.0147261071262
ko00630	Glyoxylate and dicarboxylate metabolism	1/1202	38/7206	0.0147577787652
ko03410	Base excision repair	1/1202	38/7206	0.0147577787652
ko05016	Huntington's disease	23/1202	215/7206	0.0155223547508
ko05219	Bladder cancer	2/1202	48/7206	0.01778024374
ko04115	p53 signaling pathway	5/1202	74/7206	0.0180879527206
ko04722	Neurotrophin signaling pathway	38/1202	160/7206	0.0182654306697
ko05321	Inflammatory bowel disease (IBD)	3/1202	56/7206	0.0184712859561
ko04964	Proximal tubule bicarbonate reclamation	10/1202	29/7206	0.0202593654868
ko05410	Hypertrophic cardiomyopathy (HCM)	26/1202	100/7206	0.0205550026247
ko05161	Hepatitis B	18/1202	173/7206	0.0230039226978
ko00515	Mannose type O-glycan biosynthesis	9/1202	25/7206	0.0259772091681
ko00620	Pyruvate metabolism	2/1202	46/7206	0.0263316738702
ko00280	Valine, leucine and isoleucine degradation	3/1202	54/7206	0.0263411355238
ko04966	Collecting duct acid secretion	9/1202	26/7206	0.0290679137311
ko04015	Rap1 signaling pathway	60/1202	278/7206	0.0324684576454
ko03320	PPAR signaling pathway	5/1202	69/7206	0.0339465761647
ko00640	Propanoate metabolism	1/1202	34/7206	0.0340992504901
ko04932	Non-alcoholic fatty liver disease (NAFLD)	20/1202	182/7206	0.0346011130403
ko00983	Drug metabolism - other enzymes	2/1202	42/7206	0.0364038072701
ko04670	Leukocyte transendothelial migration	16/1202	151/7206	0.0463367440771