ko	pathway	ratio_in_study	ratio_in_pop	p_value
ko05033	Nicotine addiction	26/445	56/7206	2.09897266294e-17
ko04724	Glutamatergic synapse	39/445	152/7206	6.19048097642e-15
ko04721	Synaptic vesicle cycle	28/445	80/7206	8.77010537337e-15
ko04727	GABAergic synapse	30/445	110/7206	1.69093962311e-12
ko05032	Morphine addiction	29/445	110/7206	1.01505617067e-11
ko04723	Retrograde endocannabinoid signaling	35/445	175/7206	3.33252963132e-10
ko04728	Dopaminergic synapse	35/445	185/7206	1.61436630341e-09
ko04080	Neuroactive ligand-receptor interaction	58/445	423/7206	4.2402106943e-09
ko04514	Cell adhesion molecules (CAMs)	24/445	130/7206	1.01850675175e-06
ko04713	Circadian entrainment	24/445	136/7206	2.36281018409e-06
ko05030	Cocaine addiction	16/445	73/7206	6.83762121942e-06
ko05014	Amyotrophic lateral sclerosis (ALS)	16/445	74/7206	8.23729925036e-06
ko04911	Insulin secretion	20/445	117/7206	2.67671032853e-05
ko04726	Serotonergic synapse	22/445	137/7206	2.94113041891e-05
ko04725	Cholinergic synapse	24/445	160/7206	4.09107133094e-05
ko04060	Cytokine-cytokine receptor interaction	1/445	191/7206	0.000100966233738
ko04024	cAMP signaling pathway	34/445	279/7206	0.000112710758632
ko04261	Adrenergic signaling in cardiomyocytes	27/445	205/7206	0.00016452847806
ko04744	Phototransduction	9/445	36/7206	0.000253281005678
ko04360	Axon guidance	29/445	233/7206	0.000254818321391
ko05031	Amphetamine addiction	15/445	91/7206	0.000405932216163
ko05164	Influenza A	1/445	167/7206	0.000478789935496
ko04611	Platelet activation	1/445	163/7206	0.000729946641049
ko05203	Viral carcinogenesis	5/445	277/7206	0.000796916996721
ko00604	Glycosphingolipid biosynthesis - ganglio series	5/445	14/7206	0.00110294545572
ko05166	HTLV-I infection	6/445	292/7206	0.00114225011201
ko04010	MAPK signaling pathway	34/445	321/7206	0.00183449345145
ko03013	RNA transport	2/445	166/7206	0.00294059236591
ko04961	Endocrine and other factor-regulated calcium reabsorption	10/445	59/7206	0.00297367797809
ko04120	Ubiquitin mediated proteolysis	1/445	138/7206	0.00339512725331
ko04966	Collecting duct acid secretion	6/445	26/7206	0.00427716671268
ko04720	Long-term potentiation	14/445	99/7206	0.00461011647091
ko01200	Carbon metabolism	1/445	128/7206	0.00468654660705
ko04630	Jak-STAT signaling pathway	1/445	132/7206	0.00500001315385
ko04621	NOD-like receptor signaling pathway	2/445	157/7206	0.00625374783493
ko04668	TNF signaling pathway	1/445	120/7206	0.00678185778849
ko05168	Herpes simplex infection	3/445	182/7206	0.0070543072938
ko04932	Non-alcoholic fatty liver disease (NAFLD)	3/445	182/7206	0.0070543072938
ko04970	Salivary secretion	13/445	95/7206	0.0075800700624
ko03040	Spliceosome	2/445	145/7206	0.00850121597094
ko04512	ECM-receptor interaction	11/445	79/7206	0.00879260815845
ko05205	Proteoglycans in cancer	7/445	271/7206	0.0094792239813
ko05161	Hepatitis B	3/445	173/7206	0.00958767487065
ko04742	Taste transduction	9/445	61/7206	0.0118650584072
ko04145	Phagosome	18/445	162/7206	0.0128391662301
ko04140	Autophagy - animal	3/445	164/7206	0.0132006179412
ko05120	Epithelial cell signaling in Helicobacter pylori infection	12/445	92/7206	0.0133365541363
ko04141	Protein processing in endoplasmic reticulum	4/445	184/7206	0.0187558392541
ko04260	Cardiac muscle contraction	12/445	98/7206	0.0188845866134
ko05322	Systemic lupus erythematosus	3/445	151/7206	0.0253262301364
ko04972	Pancreatic secretion	13/445	111/7206	0.0255297992956
ko04730	Long-term depression	10/445	78/7206	0.0277574800841
ko04064	NF-kappa B signaling pathway	1/445	96/7206	0.0302560165504
ko04964	Proximal tubule bicarbonate reclamation	5/445	29/7206	0.0304797737114
ko04978	Mineral absorption	6/445	40/7206	0.0344716030041
ko04066	HIF-1 signaling pathway	2/445	123/7206	0.0347232064583
ko04657	IL-17 signaling pathway	1/445	87/7206	0.0431888155343
ko04150	mTOR signaling pathway	5/445	184/7206	0.0437644928829
ko04940	Type I diabetes mellitus	5/445	32/7206	0.0444766096331
ko04931	Insulin resistance	3/445	137/7206	0.047761489461
ko04974	Protein digestion and absorption	11/445	96/7206	0.0493683640676