ko	pathway	ratio_in_study	ratio_in_pop	p_value
ko04080	Neuroactive ligand-receptor interaction	155/1014	423/7206	2.08327206615e-33
ko04724	Glutamatergic synapse	76/1014	152/7206	1.41247245188e-26
ko05033	Nicotine addiction	42/1014	56/7206	6.42112529396e-25
ko04721	Synaptic vesicle cycle	46/1014	80/7206	9.59786518312e-20
ko05032	Morphine addiction	55/1014	110/7206	1.63219340617e-19
ko04728	Dopaminergic synapse	75/1014	185/7206	2.52553820908e-19
ko04727	GABAergic synapse	54/1014	110/7206	1.03176854159e-18
ko04713	Circadian entrainment	58/1014	136/7206	2.12797561045e-16
ko04725	Cholinergic synapse	61/1014	160/7206	1.90713313119e-14
ko04723	Retrograde endocannabinoid signaling	64/1014	175/7206	4.26636319215e-14
ko04742	Taste transduction	32/1014	61/7206	1.28220305911e-12
ko04024	cAMP signaling pathway	84/1014	279/7206	1.76118271091e-12
ko04911	Insulin secretion	44/1014	117/7206	1.53218582805e-10
ko04726	Serotonergic synapse	47/1014	137/7206	2.09271671333e-09
ko04360	Axon guidance	67/1014	233/7206	3.86777047976e-09
ko03040	Spliceosome	1/1014	145/7206	9.03675026803e-09
ko05203	Viral carcinogenesis	11/1014	277/7206	2.85926736543e-08
ko04261	Adrenergic signaling in cardiomyocytes	59/1014	205/7206	3.09139001581e-08
ko04744	Phototransduction	18/1014	36/7206	2.98203399556e-07
ko05031	Amphetamine addiction	32/1014	91/7206	3.06204396458e-07
ko04060	Cytokine-cytokine receptor interaction	6/1014	191/7206	4.69871800512e-07
ko05030	Cocaine addiction	27/1014	73/7206	8.18256950428e-07
ko04921	Oxytocin signaling pathway	56/1014	209/7206	8.53292890979e-07
ko04514	Cell adhesion molecules (CAMs)	39/1014	130/7206	2.36621437932e-06
ko03013	RNA transport	5/1014	166/7206	2.37970310004e-06
ko04120	Ubiquitin mediated proteolysis	3/1014	138/7206	2.79098473508e-06
ko05168	Herpes simplex infection	7/1014	182/7206	7.0250906311e-06
ko04621	NOD-like receptor signaling pathway	5/1014	157/7206	7.21355116679e-06
ko05164	Influenza A	6/1014	167/7206	1.30417294627e-05
ko05014	Amyotrophic lateral sclerosis (ALS)	25/1014	74/7206	1.34854064765e-05
ko05322	Systemic lupus erythematosus	5/1014	151/7206	1.50011151504e-05
ko04020	Calcium signaling pathway	63/1014	265/7206	1.88633526442e-05
ko04720	Long-term potentiation	30/1014	99/7206	2.68865590803e-05
ko04970	Salivary secretion	29/1014	95/7206	3.43533227458e-05
ko05205	Proteoglycans in cancer	17/1014	271/7206	5.41066264594e-05
ko04010	MAPK signaling pathway	71/1014	321/7206	7.11735762779e-05
ko04141	Protein processing in endoplasmic reticulum	9/1014	184/7206	8.94876819314e-05
ko03008	Ribosome biogenesis in eukaryotes	1/1014	79/7206	0.000129864051913
ko00604	Glycosphingolipid biosynthesis - ganglio series	8/1014	14/7206	0.000204117563306
ko05169	Epstein-Barr virus infection	12/1014	206/7206	0.000221237856742
ko04260	Cardiac muscle contraction	27/1014	98/7206	0.000375862858839
ko05412	Arrhythmogenic right ventricular cardiomyopathy (ARVC)	23/1014	79/7206	0.000459898292709
ko04064	NF-kappa B signaling pathway	3/1014	96/7206	0.000569566333326
ko05162	Measles	5/1014	120/7206	0.000771500046912
ko04022	cGMP-PKG signaling pathway	48/1014	216/7206	0.000964889354795
ko04961	Endocrine and other factor-regulated calcium reabsorption	18/1014	59/7206	0.000995118541444
ko04972	Pancreatic secretion	28/1014	111/7206	0.00143911780425
ko04925	Aldosterone synthesis and secretion	27/1014	105/7206	0.00156385317803
ko04640	Hematopoietic cell lineage	1/1014	64/7206	0.00159007225009
ko04966	Collecting duct acid secretion	10/1014	26/7206	0.00181435164514
ko00240	Pyrimidine metabolism	5/1014	110/7206	0.00207571438687
ko05140	Leishmaniasis	2/1014	75/7206	0.0021349342806
ko04630	Jak-STAT signaling pathway	7/1014	132/7206	0.00215991731068
ko03018	RNA degradation	3/1014	84/7206	0.00245186472205
ko01200	Carbon metabolism	7/1014	128/7206	0.00290842007465
ko04971	Gastric acid secretion	25/1014	98/7206	0.00293850636335
ko04217	Necroptosis	12/1014	178/7206	0.00301218290391
ko05321	Inflammatory bowel disease (IBD)	1/1014	56/7206	0.00330539092587
ko04740	Olfactory transduction	21/1014	80/7206	0.00331371319036
ko04391	Hippo signaling pathway - fly	23/1014	90/7206	0.0033546380058
ko04964	Proximal tubule bicarbonate reclamation	10/1014	29/7206	0.00459892677465
ko04932	Non-alcoholic fatty liver disease (NAFLD)	13/1014	182/7206	0.004772152882
ko04014	Ras signaling pathway	56/1014	279/7206	0.00481112796889
ko00480	Glutathione metabolism	1/1014	55/7206	0.00518343513023
ko05161	Hepatitis B	12/1014	173/7206	0.00530098725108
ko04146	Peroxisome	4/1014	89/7206	0.00538593246627
ko00590	Arachidonic acid metabolism	1/1014	52/7206	0.00767456057153
ko04730	Long-term depression	20/1014	78/7206	0.00768617855364
ko04976	Bile secretion	20/1014	80/7206	0.00871796582335
ko00330	Arginine and proline metabolism	2/1014	61/7206	0.00914537208142
ko00561	Glycerolipid metabolism	2/1014	63/7206	0.00944837178826
ko04214	Apoptosis - fly	3/1014	72/7206	0.0101337043054
ko04110	Cell cycle	10/1014	145/7206	0.0107135461718
ko05219	Bladder cancer	1/1014	48/7206	0.0109905396568
ko03320	PPAR signaling pathway	3/1014	69/7206	0.0143376429097
ko03022	Basal transcription factors	1/1014	44/7206	0.0161826442963
ko00071	Fatty acid degradation	1/1014	45/7206	0.0162811326303
ko04072	Phospholipase D signaling pathway	40/1014	197/7206	0.0162908110581
ko03420	Nucleotide excision repair	1/1014	46/7206	0.0167711721167
ko04924	Renin secretion	20/1014	86/7206	0.0187526092716
ko04070	Phosphatidylinositol signaling system	25/1014	112/7206	0.0187553761541
ko05414	Dilated cardiomyopathy	25/1014	112/7206	0.0187553761541
ko04657	IL-17 signaling pathway	5/1014	87/7206	0.0197969827887
ko05133	Pertussis	5/1014	87/7206	0.0197969827887
ko05145	Toxoplasmosis	9/1014	126/7206	0.0199653962083
ko04612	Antigen processing and presentation	4/1014	77/7206	0.0203402586177
ko04915	Estrogen signaling pathway	28/1014	131/7206	0.0215989698546
ko04140	Autophagy - animal	13/1014	164/7206	0.0223703948076
ko04210	Apoptosis	15/1014	180/7206	0.0224548754951
ko00140	Steroid hormone biosynthesis	1/1014	41/7206	0.0239676410801
ko00983	Drug metabolism - other enzymes	1/1014	42/7206	0.0240793997458
ko00280	Valine, leucine and isoleucine degradation	2/1014	54/7206	0.0281232207338
ko04540	Gap junction	27/1014	128/7206	0.0283114970492
ko00600	Sphingolipid metabolism	3/1014	63/7206	0.0283882597432
ko01524	Platinum drug resistance	4/1014	76/7206	0.0290623769094
ko04668	TNF signaling pathway	9/1014	120/7206	0.0340457651187
ko04962	Vasopressin-regulated water reabsorption	14/1014	58/7206	0.0355331587151
ko05418	Fluid shear stress and atherosclerosis	15/1014	173/7206	0.0356700279507
ko05131	Shigellosis	5/1014	82/7206	0.0366644363692
ko04137	Mitophagy - animal	5/1014	82/7206	0.0366644363692
ko05215	Prostate cancer	8/1014	111/7206	0.0379282648852
ko00380	Tryptophan metabolism	2/1014	50/7206	0.0393473184923
ko04622	RIG-I-like receptor signaling pathway	3/1014	62/7206	0.0409114215651
ko00564	Glycerophospholipid metabolism	7/1014	99/7206	0.0414729896835
ko05146	Amoebiasis	7/1014	99/7206	0.0414729896835
ko04620	Toll-like receptor signaling pathway	7/1014	100/7206	0.0416117037467
ko05110	Vibrio cholerae infection	15/1014	63/7206	0.0423225610256
ko04933	AGE-RAGE signaling pathway in diabetic complications	11/1014	135/7206	0.0453003071762
ko04930	Type II diabetes mellitus	13/1014	54/7206	0.0466566234956
ko00533	Glycosaminoglycan biosynthesis - keratan sulfate	5/1014	15/7206	0.0485834305275