ko	pathway	ratio_in_study	ratio_in_pop	p_value
ko03040	Spliceosome	63/510	145/7206	3.80544385025e-35
ko05322	Systemic lupus erythematosus	52/510	151/7206	2.28415368881e-23
ko04110	Cell cycle	45/510	145/7206	2.6809105924e-18
ko04111	Cell cycle - yeast	35/510	90/7206	5.29164832345e-18
ko03013	RNA transport	47/510	166/7206	2.83564358133e-17
ko03440	Homologous recombination	21/510	41/7206	3.35277064365e-14
ko04080	Neuroactive ligand-receptor interaction	1/510	423/7206	6.6328043521e-13
ko03460	Fanconi anemia pathway	22/510	51/7206	7.22692227789e-13
ko05034	Alcoholism	50/510	238/7206	1.13889717198e-12
ko04113	Meiosis - yeast	25/510	70/7206	3.17948240521e-12
ko03030	DNA replication	17/510	38/7206	1.54178377785e-10
ko03008	Ribosome biogenesis in eukaryotes	23/510	79/7206	2.49563743591e-09
ko05203	Viral carcinogenesis	48/510	277/7206	4.62749992176e-09
ko04144	Endocytosis	3/510	342/7206	5.51508697522e-08
ko03430	Mismatch repair	10/510	22/7206	8.59817773721e-07
ko04114	Oocyte meiosis	27/510	139/7206	1.11324342563e-06
ko00240	Pyrimidine metabolism	23/510	110/7206	1.86712604305e-06
ko04024	cAMP signaling pathway	3/510	279/7206	3.66777922162e-06
ko04921	Oxytocin signaling pathway	1/510	209/7206	6.37725339908e-06
ko03410	Base excision repair	12/510	38/7206	6.85152790608e-06
ko04020	Calcium signaling pathway	3/510	265/7206	7.51898599047e-06
ko05010	Alzheimer's disease	1/510	202/7206	9.2208515731e-06
ko04151	PI3K-Akt signaling pathway	8/510	390/7206	9.4669077591e-06
ko03018	RNA degradation	18/510	84/7206	1.72868920719e-05
ko04060	Cytokine-cytokine receptor interaction	1/510	191/7206	2.03602013586e-05
ko03015	mRNA surveillance pathway	19/510	93/7206	2.08264417277e-05
ko04728	Dopaminergic synapse	1/510	185/7206	3.00136786442e-05
ko04022	cGMP-PKG signaling pathway	2/510	216/7206	3.48330074379e-05
ko03022	Basal transcription factors	12/510	44/7206	3.6052759767e-05
ko03420	Nucleotide excision repair	12/510	46/7206	5.83741048751e-05
ko04261	Adrenergic signaling in cardiomyocytes	2/510	205/7206	7.45918192485e-05
ko04120	Ubiquitin mediated proteolysis	23/510	138/7206	0.00012593582699
ko04611	Platelet activation	1/510	163/7206	0.000144188177554
ko05012	Parkinson's disease	1/510	155/7206	0.000209959615004
ko04621	NOD-like receptor signaling pathway	1/510	157/7206	0.000211633656964
ko05152	Tuberculosis	2/510	187/7206	0.000224674667848
ko04725	Cholinergic synapse	1/510	160/7206	0.000225630779418
ko04932	Non-alcoholic fatty liver disease (NAFLD)	2/510	182/7206	0.000329505638969
ko04371	Apelin signaling pathway	2/510	177/7206	0.000483647886765
ko04510	Focal adhesion	5/510	240/7206	0.000765804494837
ko05202	Transcriptional misregulation in cancer	26/510	188/7206	0.00080684745081
ko04810	Regulation of actin cytoskeleton	6/510	264/7206	0.000826850624381
ko05166	HTLV-I infection	36/510	292/7206	0.000973715027971
ko04010	MAPK signaling pathway	9/510	321/7206	0.00112130721428
ko04914	Progesterone-mediated oocyte maturation	17/510	104/7206	0.00137366083012
ko01200	Carbon metabolism	1/510	128/7206	0.00144377932034
ko05142	Chagas disease (American trypanosomiasis)	1/510	130/7206	0.00147569861739
ko04915	Estrogen signaling pathway	1/510	131/7206	0.0015061590854
ko05205	Proteoglycans in cancer	7/510	271/7206	0.00154986891645
ko04062	Chemokine signaling pathway	4/510	201/7206	0.001907472678
ko04750	Inflammatory mediator regulation of TRP channels	1/510	122/7206	0.00211252868448
ko04072	Phospholipase D signaling pathway	4/510	197/7206	0.00270204266947
ko04014	Ras signaling pathway	8/510	279/7206	0.00277655045324
ko04911	Insulin secretion	1/510	117/7206	0.00309909196681
ko03020	RNA polymerase	7/510	29/7206	0.00338482592036
ko05167	Kaposi's sarcoma-associated herpesvirus infection	4/510	191/7206	0.00374845727682
ko04015	Rap1 signaling pathway	8/510	278/7206	0.00383015174365
ko05414	Dilated cardiomyopathy	1/510	112/7206	0.00455171601142
ko04071	Sphingolipid signaling pathway	3/510	162/7206	0.00475049189928
ko04630	Jak-STAT signaling pathway	2/510	132/7206	0.00581834433196
ko04380	Osteoclast differentiation	2/510	134/7206	0.00583700929663
ko04931	Insulin resistance	2/510	137/7206	0.00607694157027
ko04726	Serotonergic synapse	2/510	137/7206	0.00607694157027
ko04142	Lysosome	3/510	151/7206	0.00935889138616
ko05410	Hypertrophic cardiomyopathy (HCM)	1/510	100/7206	0.00961939173049
ko04620	Toll-like receptor signaling pathway	1/510	100/7206	0.00961939173049
ko05418	Fluid shear stress and atherosclerosis	4/510	173/7206	0.00984490856431
ko04912	GnRH signaling pathway	2/510	122/7206	0.0117791432647
ko04530	Tight junction	7/510	228/7206	0.012286873726
ko04140	Autophagy - animal	4/510	164/7206	0.0133225992652
ko05164	Influenza A	4/510	167/7206	0.013500815032
ko04970	Salivary secretion	1/510	95/7206	0.0140620578217
ko04658	Th1 and Th2 cell differentiation	1/510	96/7206	0.0142365365765
ko05200	Pathways in cancer	22/510	492/7206	0.0176489666099
ko04141	Protein processing in endoplasmic reticulum	5/510	184/7206	0.0184433425222
ko04152	AMPK signaling pathway	4/510	161/7206	0.0184517989296
ko04146	Peroxisome	1/510	89/7206	0.0203549833797
ko05323	Rheumatoid arthritis	1/510	89/7206	0.0203549833797
ko04070	Phosphatidylinositol signaling system	2/510	112/7206	0.0238522726304
ko04933	AGE-RAGE signaling pathway in diabetic complications	3/510	135/7206	0.0255200757827
ko01230	Biosynthesis of amino acids	1/510	85/7206	0.0300932372946
ko00534	Glycosaminoglycan biosynthesis - heparan sulfate / heparin	5/510	26/7206	0.033155194989
ko04925	Aldosterone synthesis and secretion	2/510	105/7206	0.0332558756425
ko04659	Th17 cell differentiation	2/510	106/7206	0.033515289897
ko04922	Glucagon signaling pathway	3/510	128/7206	0.0347199290984
ko04540	Gap junction	3/510	128/7206	0.0347199290984
ko04514	Cell adhesion molecules (CAMs)	3/510	130/7206	0.0356231405587
ko04923	Regulation of lipolysis in adipocytes	1/510	77/7206	0.0424715304816
ko04730	Long-term depression	1/510	78/7206	0.0427825270502
ko04145	Phagosome	5/510	162/7206	0.0431335743452
ko05412	Arrhythmogenic right ventricular cardiomyopathy (ARVC)	1/510	79/7206	0.0432958128428
ko04139	Mitophagy - yeast	6/510	37/7206	0.043497539142
ko05132	Salmonella infection	2/510	98/7206	0.0464624573777
ko04720	Long-term potentiation	2/510	99/7206	0.0466203197375
ko00564	Glycerophospholipid metabolism	2/510	99/7206	0.0466203197375
ko05162	Measles	3/510	120/7206	0.0470304384104
ko04066	HIF-1 signaling pathway	3/510	123/7206	0.0481405887293
ko01522	Endocrine resistance	3/510	124/7206	0.0487903150524