ko	pathway	ratio_in_study	ratio_in_pop	p_value
ko04080	Neuroactive ligand-receptor interaction	157/1006	423/7206	4.65032489978e-35
ko05033	Nicotine addiction	43/1006	56/7206	2.34887733997e-26
ko04724	Glutamatergic synapse	75/1006	152/7206	5.43202921365e-26
ko05032	Morphine addiction	55/1006	110/7206	1.11829186428e-19
ko04713	Circadian entrainment	61/1006	136/7206	1.11933790834e-18
ko04721	Synaptic vesicle cycle	44/1006	80/7206	4.72574550161e-18
ko04728	Dopaminergic synapse	71/1006	185/7206	5.31675936316e-17
ko04727	GABAergic synapse	51/1006	110/7206	1.48635011214e-16
ko04725	Cholinergic synapse	61/1006	160/7206	1.31412998065e-14
ko04723	Retrograde endocannabinoid signaling	64/1006	175/7206	2.9109484985e-14
ko04024	cAMP signaling pathway	85/1006	279/7206	3.64485901612e-13
ko04020	Calcium signaling pathway	80/1006	265/7206	3.14507504669e-12
ko04921	Oxytocin signaling pathway	66/1006	209/7206	3.6227983329e-11
ko04744	Phototransduction	21/1006	36/7206	6.27713306501e-10
ko04726	Serotonergic synapse	47/1006	137/7206	1.01591731379e-09
ko04911	Insulin secretion	42/1006	117/7206	1.6636007653e-09
ko05031	Amphetamine addiction	35/1006	91/7206	4.78495122229e-09
ko04261	Adrenergic signaling in cardiomyocytes	60/1006	205/7206	7.7422929813e-09
ko03040	Spliceosome	1/1006	145/7206	1.50188085603e-08
ko04742	Taste transduction	26/1006	61/7206	3.92028356954e-08
ko04970	Salivary secretion	34/1006	95/7206	6.54652140017e-08
ko04720	Long-term potentiation	34/1006	99/7206	2.07191820251e-07
ko05203	Viral carcinogenesis	13/1006	277/7206	5.28380888028e-07
ko05014	Amyotrophic lateral sclerosis (ALS)	26/1006	74/7206	3.44065992752e-06
ko03013	RNA transport	5/1006	166/7206	3.66205200458e-06
ko05322	Systemic lupus erythematosus	4/1006	151/7206	4.00312623497e-06
ko04514	Cell adhesion molecules (CAMs)	38/1006	130/7206	4.66077325062e-06
ko04022	cGMP-PKG signaling pathway	55/1006	216/7206	5.28916051651e-06
ko04360	Axon guidance	57/1006	233/7206	1.24093785062e-05
ko04966	Collecting duct acid secretion	13/1006	26/7206	1.26052154831e-05
ko04010	MAPK signaling pathway	73/1006	321/7206	1.53087415839e-05
ko04120	Ubiquitin mediated proteolysis	4/1006	138/7206	1.7616887895e-05
ko04925	Aldosterone synthesis and secretion	31/1006	105/7206	2.68172766489e-05
ko05168	Herpes simplex infection	8/1006	182/7206	3.11410848312e-05
ko05030	Cocaine addiction	24/1006	73/7206	4.53324585296e-05
ko04060	Cytokine-cytokine receptor interaction	9/1006	191/7206	4.63444829941e-05
ko04971	Gastric acid secretion	29/1006	98/7206	4.86730891316e-05
ko04964	Proximal tubule bicarbonate reclamation	13/1006	29/7206	5.47425630237e-05
ko05164	Influenza A	7/1006	167/7206	5.89928675402e-05
ko04745	Phototransduction - fly	15/1006	38/7206	8.92393879748e-05
ko04730	Long-term depression	24/1006	78/7206	0.000104808623059
ko04070	Phosphatidylinositol signaling system	31/1006	112/7206	0.000147101734432
ko04621	NOD-like receptor signaling pathway	7/1006	157/7206	0.000158968340083
ko04612	Antigen processing and presentation	1/1006	77/7206	0.000197060501886
ko03008	Ribosome biogenesis in eukaryotes	1/1006	79/7206	0.000212016327603
ko04740	Olfactory transduction	24/1006	80/7206	0.000229749618401
ko04972	Pancreatic secretion	30/1006	111/7206	0.000255160355184
ko04014	Ras signaling pathway	61/1006	279/7206	0.00027264976897
ko05412	Arrhythmogenic right ventricular cardiomyopathy (ARVC)	23/1006	79/7206	0.000426423989628
ko04710	Circadian rhythm	15/1006	43/7206	0.00044241523306
ko05162	Measles	5/1006	120/7206	0.00075620848145
ko04141	Protein processing in endoplasmic reticulum	11/1006	184/7206	0.000763179470913
ko05205	Proteoglycans in cancer	20/1006	271/7206	0.0008858867249
ko05169	Epstein-Barr virus infection	14/1006	206/7206	0.00149267436359
ko04924	Renin secretion	23/1006	86/7206	0.00149309250673
ko04110	Cell cycle	8/1006	145/7206	0.00153599756877
ko04626	Plant-pathogen interaction	8/1006	18/7206	0.00167275893794
ko04146	Peroxisome	3/1006	89/7206	0.00174607285399
ko04260	Cardiac muscle contraction	25/1006	98/7206	0.00190970724858
ko05140	Leishmaniasis	2/1006	75/7206	0.00210088358923
ko05110	Vibrio cholerae infection	18/1006	63/7206	0.00266380753097
ko04371	Apelin signaling pathway	39/1006	177/7206	0.0028863734536
ko04976	Bile secretion	21/1006	80/7206	0.00309819435349
ko04540	Gap junction	30/1006	128/7206	0.00418161260516
ko04072	Phospholipase D signaling pathway	42/1006	197/7206	0.00459304125835
ko00280	Valine, leucine and isoleucine degradation	1/1006	54/7206	0.00497247096681
ko05161	Hepatitis B	12/1006	173/7206	0.00523352252029
ko00562	Inositol phosphate metabolism	22/1006	89/7206	0.00542073279368
ko05016	Huntington's disease	17/1006	215/7206	0.00692803566955
ko04750	Inflammatory mediator regulation of TRP channels	28/1006	122/7206	0.00772860393733
ko00604	Glycosphingolipid biosynthesis - ganglio series	6/1006	14/7206	0.0080478121175
ko05166	HTLV-I infection	26/1006	292/7206	0.00952946404569
ko04064	NF-kappa B signaling pathway	5/1006	96/7206	0.0107950042797
ko00260	Glycine, serine and threonine metabolism	1/1006	48/7206	0.0109747553401
ko05219	Bladder cancer	1/1006	48/7206	0.0109747553401
ko05410	Hypertrophic cardiomyopathy (HCM)	23/1006	100/7206	0.0128811784569
ko00330	Arginine and proline metabolism	2/1006	61/7206	0.0139658127023
ko04630	Jak-STAT signaling pathway	9/1006	132/7206	0.0153378810899
ko04217	Necroptosis	14/1006	178/7206	0.0156140370681
ko00071	Fatty acid degradation	1/1006	45/7206	0.0162670493321
ko03420	Nucleotide excision repair	1/1006	46/7206	0.0166153996611
ko00240	Pyrimidine metabolism	7/1006	110/7206	0.0178027812855
ko05414	Dilated cardiomyopathy	25/1006	112/7206	0.0183561526518
ko04610	Complement and coagulation cascades	4/1006	79/7206	0.0207890883481
ko04915	Estrogen signaling pathway	28/1006	131/7206	0.020998235025
ko05120	Epithelial cell signaling in Helicobacter pylori infection	21/1006	92/7206	0.0216823132741
ko04960	Aldosterone-regulated sodium reabsorption	11/1006	41/7206	0.0237979591755
ko03022	Basal transcription factors	1/1006	44/7206	0.0255705440843
ko04711	Circadian rhythm - fly	5/1006	13/7206	0.0256276775994
ko05145	Toxoplasmosis	9/1006	126/7206	0.0264836009513
ko04922	Glucagon signaling pathway	27/1006	128/7206	0.0275509326386
ko04657	IL-17 signaling pathway	5/1006	87/7206	0.0276828731618
ko04510	Focal adhesion	22/1006	240/7206	0.0290003881438
ko04015	Rap1 signaling pathway	51/1006	278/7206	0.0342532206965
ko04214	Apoptosis - fly	4/1006	72/7206	0.0388672291594
ko00380	Tryptophan metabolism	2/1006	50/7206	0.0393078279923
ko04330	Notch signaling pathway	3/1006	62/7206	0.0405398625514
ko04622	RIG-I-like receptor signaling pathway	3/1006	62/7206	0.0405398625514
ko04930	Type II diabetes mellitus	13/1006	54/7206	0.0455146634343
ko04210	Apoptosis	16/1006	180/7206	0.0493491452614