ko	pathway	ratio_in_study	ratio_in_pop	p_value
ko04080	Neuroactive ligand-receptor interaction	115/923	423/7206	2.93605337548e-16
ko04724	Glutamatergic synapse	55/923	152/7206	8.90152319805e-14
ko04727	GABAergic synapse	41/923	110/7206	4.63672279907e-11
ko04713	Circadian entrainment	44/923	136/7206	1.81184647634e-09
ko05033	Nicotine addiction	25/923	56/7206	3.86651324817e-09
ko05032	Morphine addiction	37/923	110/7206	1.10688944156e-08
ko04911	Insulin secretion	37/923	117/7206	7.03980412747e-08
ko03040	Spliceosome	1/923	145/7206	9.38866922214e-08
ko04020	Calcium signaling pathway	65/923	265/7206	1.01518384357e-07
ko05322	Systemic lupus erythematosus	2/923	151/7206	4.1084743962e-07
ko04725	Cholinergic synapse	44/923	160/7206	4.64873690152e-07
ko04728	Dopaminergic synapse	49/923	185/7206	4.97017915619e-07
ko03010	Ribosome	1/923	129/7206	7.29750110583e-07
ko04726	Serotonergic synapse	39/923	137/7206	8.15434497373e-07
ko04970	Salivary secretion	30/923	95/7206	1.26249836282e-06
ko04925	Aldosterone synthesis and secretion	32/923	105/7206	1.85877175515e-06
ko04721	Synaptic vesicle cycle	26/923	80/7206	3.53217823428e-06
ko05031	Amphetamine addiction	28/923	91/7206	5.02331870648e-06
ko04723	Retrograde endocannabinoid signaling	43/923	175/7206	1.6466177461e-05
ko03013	RNA transport	5/923	166/7206	1.69244964589e-05
ko04024	cAMP signaling pathway	61/923	279/7206	2.12666587412e-05
ko04110	Cell cycle	4/923	145/7206	4.18444779789e-05
ko04022	cGMP-PKG signaling pathway	49/923	216/7206	4.50705999826e-05
ko04720	Long-term potentiation	28/923	99/7206	4.74232095957e-05
ko05203	Viral carcinogenesis	15/923	277/7206	4.85350159456e-05
ko04921	Oxytocin signaling pathway	47/923	209/7206	8.40128552552e-05
ko04971	Gastric acid secretion	27/923	98/7206	8.74482924042e-05
ko04966	Collecting duct acid secretion	11/923	26/7206	0.000177194530625
ko04730	Long-term depression	22/923	78/7206	0.000235257501841
ko04514	Cell adhesion molecules (CAMs)	32/923	130/7206	0.000267255663755
ko04964	Proximal tubule bicarbonate reclamation	11/923	29/7206	0.000550985320102
ko04745	Phototransduction - fly	13/923	38/7206	0.000566781860007
ko04710	Circadian rhythm	14/923	43/7206	0.000622405038585
ko05168	Herpes simplex infection	9/923	182/7206	0.000653576317394
ko05030	Cocaine addiction	20/923	73/7206	0.00066151904005
ko04070	Phosphatidylinositol signaling system	27/923	112/7206	0.000887503652004
ko04744	Phototransduction	12/923	36/7206	0.00119365356337
ko04972	Pancreatic secretion	26/923	111/7206	0.00223921252501
ko04261	Adrenergic signaling in cardiomyocytes	41/923	205/7206	0.00289305223727
ko05169	Epstein-Barr virus infection	13/923	206/7206	0.00294132122991
ko04976	Bile secretion	20/923	80/7206	0.00346155728111
ko05016	Huntington's disease	14/923	215/7206	0.00353864660189
ko04960	Aldosterone-regulated sodium reabsorption	12/923	41/7206	0.00410573353992
ko04371	Apelin signaling pathway	36/923	177/7206	0.00415679683155
ko04120	Ubiquitin mediated proteolysis	7/923	138/7206	0.00425085744011
ko04072	Phospholipase D signaling pathway	39/923	197/7206	0.00472157952247
ko04742	Taste transduction	16/923	61/7206	0.00568025259781
ko05110	Vibrio cholerae infection	16/923	63/7206	0.00659346530609
ko04141	Protein processing in endoplasmic reticulum	12/923	184/7206	0.00714063483708
ko00643	Styrene degradation	3/923	4/7206	0.00757910563091
ko05224	Breast cancer	11/923	174/7206	0.00784265366643
ko04750	Inflammatory mediator regulation of TRP channels	26/923	122/7206	0.00865564462262
ko00120	Primary bile acid biosynthesis	7/923	20/7206	0.00945249577132
ko04270	Vascular smooth muscle contraction	31/923	154/7206	0.00987778099815
ko03050	Proteasome	1/923	54/7206	0.0120282585305
ko00280	Valine, leucine and isoleucine degradation	1/923	54/7206	0.0120282585305
ko05014	Amyotrophic lateral sclerosis (ALS)	17/923	74/7206	0.0134881566694
ko05130	Pathogenic Escherichia coli infection	3/923	77/7206	0.0151495609574
ko04657	IL-17 signaling pathway	4/923	87/7206	0.015360920453
ko04961	Endocrine and other factor-regulated calcium reabsorption	14/923	59/7206	0.0178340094213
ko04932	Non-alcoholic fatty liver disease (NAFLD)	13/923	182/7206	0.0180066966598
ko04510	Focal adhesion	19/923	240/7206	0.018320110126
ko05162	Measles	7/923	120/7206	0.0185016694344
ko05211	Renal cell carcinoma	5/923	96/7206	0.0206127959286
ko04360	Axon guidance	42/923	233/7206	0.0213239504059
ko04014	Ras signaling pathway	49/923	279/7206	0.0218476979545
ko04810	Regulation of actin cytoskeleton	22/923	264/7206	0.024268913222
ko03420	Nucleotide excision repair	1/923	46/7206	0.0250297344689
ko05200	Pathways in cancer	47/923	492/7206	0.0251394613197
ko04922	Glucagon signaling pathway	25/923	128/7206	0.0314099010249
ko04540	Gap junction	25/923	128/7206	0.0314099010249
ko05205	Proteoglycans in cancer	23/923	271/7206	0.0325002157935
ko04924	Renin secretion	18/923	86/7206	0.033064974816
ko04918	Thyroid hormone synthesis	18/923	86/7206	0.033064974816
ko05161	Hepatitis B	13/923	173/7206	0.0373029199017
ko05222	Small cell lung cancer	5/923	89/7206	0.0377838513807
ko05166	HTLV-I infection	26/923	292/7206	0.0398303297913
ko00520	Amino sugar and nucleotide sugar metabolism	2/923	55/7206	0.0407639254022