ko	pathway	ratio_in_study	ratio_in_pop	p_value
ko04080	Neuroactive ligand-receptor interaction	184/1214	423/7206	1.15405691595e-40
ko04724	Glutamatergic synapse	83/1214	152/7206	8.2219889033e-27
ko05033	Nicotine addiction	44/1214	56/7206	3.32199801563e-24
ko04713	Circadian entrainment	72/1214	136/7206	2.58183954474e-22
ko05032	Morphine addiction	62/1214	110/7206	2.94867468553e-21
ko04727	GABAergic synapse	58/1214	110/7206	4.3858335327e-18
ko04728	Dopaminergic synapse	80/1214	185/7206	1.09607534653e-17
ko04020	Calcium signaling pathway	101/1214	265/7206	3.0913432261e-17
ko04725	Cholinergic synapse	72/1214	160/7206	3.56502080047e-17
ko04721	Synaptic vesicle cycle	43/1214	80/7206	4.02196333458e-14
ko04024	cAMP signaling pathway	98/1214	279/7206	4.32904773352e-14
ko04723	Retrograde endocannabinoid signaling	71/1214	175/7206	4.86422535843e-14
ko04911	Insulin secretion	54/1214	117/7206	9.57964814762e-14
ko04921	Oxytocin signaling pathway	79/1214	209/7206	1.56070483912e-13
ko04726	Serotonergic synapse	59/1214	137/7206	2.94739390947e-13
ko04742	Taste transduction	33/1214	61/7206	3.04372871262e-11
ko05031	Amphetamine addiction	40/1214	91/7206	9.93217105088e-10
ko04970	Salivary secretion	41/1214	95/7206	1.20792148658e-09
ko03010	Ribosome	1/1214	129/7206	1.54051222428e-09
ko04720	Long-term potentiation	41/1214	99/7206	5.34198008358e-09
ko05322	Systemic lupus erythematosus	3/1214	151/7206	7.12994200167e-09
ko03040	Spliceosome	3/1214	145/7206	1.53669890657e-08
ko04744	Phototransduction	21/1214	36/7206	2.08038028715e-08
ko04022	cGMP-PKG signaling pathway	69/1214	216/7206	2.99326639543e-08
ko04261	Adrenergic signaling in cardiomyocytes	66/1214	205/7206	4.10450704109e-08
ko04925	Aldosterone synthesis and secretion	41/1214	105/7206	4.36736822073e-08
ko04971	Gastric acid secretion	38/1214	98/7206	1.69274109042e-07
ko05203	Viral carcinogenesis	19/1214	277/7206	1.03314731534e-06
ko04070	Phosphatidylinositol signaling system	40/1214	112/7206	1.2097376344e-06
ko03013	RNA transport	8/1214	166/7206	2.89211045118e-06
ko04730	Long-term depression	30/1214	78/7206	4.36342815015e-06
ko04745	Phototransduction - fly	18/1214	38/7206	1.18767798733e-05
ko04072	Phospholipase D signaling pathway	57/1214	197/7206	1.76060575907e-05
ko04710	Circadian rhythm	19/1214	43/7206	2.36166350703e-05
ko05030	Cocaine addiction	27/1214	73/7206	2.80959193812e-05
ko04010	MAPK signaling pathway	83/1214	321/7206	3.33036308143e-05
ko04360	Axon guidance	64/1214	233/7206	3.61101807623e-05
ko05164	Influenza A	10/1214	167/7206	3.6713410854e-05
ko05168	Herpes simplex infection	12/1214	182/7206	5.12578706911e-05
ko04621	NOD-like receptor signaling pathway	9/1214	157/7206	5.16927730692e-05
ko04972	Pancreatic secretion	36/1214	111/7206	5.23930265908e-05
ko03008	Ribosome biogenesis in eukaryotes	2/1214	79/7206	0.000110056467541
ko05014	Amyotrophic lateral sclerosis (ALS)	26/1214	74/7206	0.000120457923556
ko04120	Ubiquitin mediated proteolysis	8/1214	138/7206	0.000131703406721
ko04110	Cell cycle	9/1214	145/7206	0.000187033312487
ko04514	Cell adhesion molecules (CAMs)	39/1214	130/7206	0.000197292240957
ko04750	Inflammatory mediator regulation of TRP channels	37/1214	122/7206	0.0002035993561
ko04740	Olfactory transduction	27/1214	80/7206	0.000219440091329
ko04014	Ras signaling pathway	71/1214	279/7206	0.000219468172428
ko04371	Apelin signaling pathway	49/1214	177/7206	0.00022934068144
ko04141	Protein processing in endoplasmic reticulum	14/1214	184/7206	0.000300742475452
ko05412	Arrhythmogenic right ventricular cardiomyopathy (ARVC)	26/1214	79/7206	0.000405974841516
ko04922	Glucagon signaling pathway	37/1214	128/7206	0.000724007121003
ko04540	Gap junction	37/1214	128/7206	0.000724007121003
ko04976	Bile secretion	26/1214	80/7206	0.000734062519179
ko04060	Cytokine-cytokine receptor interaction	16/1214	191/7206	0.000820552459561
ko04064	NF-kappa B signaling pathway	5/1214	96/7206	0.000877368258788
ko05169	Epstein-Barr virus infection	18/1214	206/7206	0.00090484604778
ko04270	Vascular smooth muscle contraction	42/1214	154/7206	0.0009957202681
ko05140	Leishmaniasis	3/1214	75/7206	0.00100213738384
ko04612	Antigen processing and presentation	3/1214	77/7206	0.00103776137907
ko04964	Proximal tubule bicarbonate reclamation	12/1214	29/7206	0.0015444308758
ko04966	Collecting duct acid secretion	11/1214	26/7206	0.00195024092696
ko04924	Renin secretion	26/1214	86/7206	0.00200346095596
ko04915	Estrogen signaling pathway	36/1214	131/7206	0.00200664152131
ko04711	Circadian rhythm - fly	7/1214	13/7206	0.00253259693609
ko05161	Hepatitis B	15/1214	173/7206	0.00268726509163
ko04930	Type II diabetes mellitus	18/1214	54/7206	0.00284900374031
ko04217	Necroptosis	16/1214	178/7206	0.00316266612947
ko05016	Huntington's disease	21/1214	215/7206	0.00396082299957
ko03022	Basal transcription factors	1/1214	44/7206	0.00432242903848
ko05144	Malaria	1/1214	45/7206	0.0043270706018
ko05162	Measles	9/1214	120/7206	0.0043273759013
ko03420	Nucleotide excision repair	1/1214	46/7206	0.00450926895424
ko00280	Valine, leucine and isoleucine degradation	2/1214	54/7206	0.00555319672393
ko04626	Plant-pathogen interaction	8/1214	18/7206	0.00565186142393
ko04630	Jak-STAT signaling pathway	11/1214	132/7206	0.00661120792069
ko05414	Dilated cardiomyopathy	30/1214	112/7206	0.00717139588201
ko04657	IL-17 signaling pathway	6/1214	87/7206	0.00917382204214
ko05133	Pertussis	6/1214	87/7206	0.00917382204214
ko04622	RIG-I-like receptor signaling pathway	3/1214	62/7206	0.00936430927738
ko05110	Vibrio cholerae infection	19/1214	63/7206	0.00988429709008
ko04015	Rap1 signaling pathway	63/1214	278/7206	0.0110622818912
ko05145	Toxoplasmosis	11/1214	126/7206	0.0114345884168
ko05166	HTLV-I infection	34/1214	292/7206	0.0133454444869
ko04260	Cardiac muscle contraction	26/1214	98/7206	0.0139361090403
ko00562	Inositol phosphate metabolism	24/1214	89/7206	0.0147598436964
ko03410	Base excision repair	1/1214	38/7206	0.0148121564933
ko05205	Proteoglycans in cancer	31/1214	271/7206	0.0161015707923
ko05131	Shigellosis	6/1214	82/7206	0.0171144287315
ko05219	Bladder cancer	2/1214	48/7206	0.0180321644102
ko04960	Aldosterone-regulated sodium reabsorption	13/1214	41/7206	0.0188601296834
ko05231	Choline metabolism in cancer	33/1214	134/7206	0.0194097217553
ko00604	Glycosphingolipid biosynthesis - ganglio series	6/1214	14/7206	0.0199591456044
ko04923	Regulation of lipolysis in adipocytes	21/1214	77/7206	0.0205317422184
ko05410	Hypertrophic cardiomyopathy (HCM)	26/1214	100/7206	0.0211063483925
ko04973	Carbohydrate digestion and absorption	13/1214	42/7206	0.0214033851352
ko04146	Peroxisome	7/1214	89/7206	0.0217024375218
ko04113	Meiosis - yeast	5/1214	70/7206	0.0247050569569
ko04214	Apoptosis - fly	5/1214	72/7206	0.0251872633669
ko05214	Glioma	21/1214	79/7206	0.0326260630994
ko04962	Vasopressin-regulated water reabsorption	16/1214	58/7206	0.0343662644652
ko00860	Porphyrin and chlorophyll metabolism	1/1214	34/7206	0.0345630484155
ko04115	p53 signaling pathway	6/1214	74/7206	0.0421654970087
ko04210	Apoptosis	20/1214	180/7206	0.0429409589669
ko05222	Small cell lung cancer	8/1214	89/7206	0.0458091975364
ko05340	Primary immunodeficiency	1/1214	30/7206	0.0486292276023
ko05321	Inflammatory bowel disease (IBD)	4/1214	56/7206	0.0491748646248