ko	pathway	ratio_in_study	ratio_in_pop	p_value
ko04080	Neuroactive ligand-receptor interaction	178/1133	423/7206	2.80031511497e-41
ko04724	Glutamatergic synapse	87/1133	152/7206	1.91469389877e-32
ko05033	Nicotine addiction	48/1133	56/7206	4.54085625141e-31
ko05032	Morphine addiction	67/1133	110/7206	2.0713201829e-27
ko04713	Circadian entrainment	73/1133	136/7206	5.49414157152e-25
ko04727	GABAergic synapse	64/1133	110/7206	1.19419342143e-24
ko04728	Dopaminergic synapse	82/1133	185/7206	7.32496688117e-21
ko04725	Cholinergic synapse	73/1133	160/7206	1.4377601224e-19
ko04723	Retrograde endocannabinoid signaling	77/1133	175/7206	2.04756826749e-19
ko04721	Synaptic vesicle cycle	46/1133	80/7206	9.28205387379e-18
ko04024	cAMP signaling pathway	100/1133	279/7206	5.32649526865e-17
ko04744	Phototransduction	28/1133	36/7206	2.0030884681e-16
ko04020	Calcium signaling pathway	92/1133	265/7206	9.32003699667e-15
ko04742	Taste transduction	36/1133	61/7206	1.15777945908e-14
ko04921	Oxytocin signaling pathway	77/1133	209/7206	4.04011619578e-14
ko04911	Insulin secretion	50/1133	117/7206	1.97238702646e-12
ko04726	Serotonergic synapse	54/1133	137/7206	1.22071063999e-11
ko04261	Adrenergic signaling in cardiomyocytes	69/1133	205/7206	1.30730200418e-10
ko05031	Amphetamine addiction	38/1133	91/7206	2.04315244215e-09
ko04720	Long-term potentiation	40/1133	99/7206	2.46906176215e-09
ko04970	Salivary secretion	38/1133	95/7206	8.64718214307e-09
ko05203	Viral carcinogenesis	13/1133	277/7206	9.78863732604e-09
ko03040	Spliceosome	2/1133	145/7206	1.03984101511e-08
ko03010	Ribosome	1/1133	129/7206	1.10295359794e-08
ko04740	Olfactory transduction	32/1133	80/7206	1.2991281957e-07
ko04022	cGMP-PKG signaling pathway	64/1133	216/7206	1.79136595399e-07
ko04925	Aldosterone synthesis and secretion	37/1133	105/7206	9.14866607139e-07
ko05014	Amyotrophic lateral sclerosis (ALS)	28/1133	74/7206	2.94451107551e-06
ko03013	RNA transport	7/1133	166/7206	4.13618378391e-06
ko05168	Herpes simplex infection	9/1133	182/7206	7.24568362497e-06
ko05322	Systemic lupus erythematosus	6/1133	151/7206	7.34144668271e-06
ko04966	Collecting duct acid secretion	14/1133	26/7206	7.80590423476e-06
ko04971	Gastric acid secretion	33/1133	98/7206	8.70859204284e-06
ko05030	Cocaine addiction	27/1133	73/7206	1.08111198787e-05
ko04060	Cytokine-cytokine receptor interaction	10/1133	191/7206	1.10553993569e-05
ko04010	MAPK signaling pathway	80/1133	321/7206	1.36320609618e-05
ko05412	Arrhythmogenic right ventricular cardiomyopathy (ARVC)	28/1133	79/7206	1.39616587132e-05
ko04514	Cell adhesion molecules (CAMs)	40/1133	130/7206	1.40047452016e-05
ko04745	Phototransduction - fly	17/1133	38/7206	2.07664416451e-05
ko04070	Phosphatidylinositol signaling system	35/1133	112/7206	3.38163276281e-05
ko04621	NOD-like receptor signaling pathway	8/1133	157/7206	5.26876122295e-05
ko04360	Axon guidance	60/1133	233/7206	7.08236936667e-05
ko04072	Phospholipase D signaling pathway	52/1133	197/7206	9.34642023837e-05
ko04730	Long-term depression	26/1133	78/7206	0.000109041779538
ko05205	Proteoglycans in cancer	21/1133	271/7206	0.000114369818479
ko04120	Ubiquitin mediated proteolysis	7/1133	138/7206	0.000137687496949
ko05164	Influenza A	10/1133	167/7206	0.000148609153487
ko04064	NF-kappa B signaling pathway	3/1133	96/7206	0.000173552012969
ko05414	Dilated cardiomyopathy	33/1133	112/7206	0.000200474158545
ko04110	Cell cycle	8/1133	145/7206	0.000200851493939
ko04260	Cardiac muscle contraction	30/1133	98/7206	0.000205376445994
ko04610	Complement and coagulation cascades	2/1133	79/7206	0.000266002765665
ko03008	Ribosome biogenesis in eukaryotes	2/1133	79/7206	0.000266002765665
ko05161	Hepatitis B	11/1133	173/7206	0.00027917130099
ko04371	Apelin signaling pathway	46/1133	177/7206	0.000344031218038
ko05169	Epstein-Barr virus infection	15/1133	206/7206	0.000419574543271
ko04710	Circadian rhythm	16/1133	43/7206	0.000490063529412
ko05140	Leishmaniasis	2/1133	75/7206	0.000604736608091
ko05166	HTLV-I infection	26/1133	292/7206	0.000717893444987
ko04626	Plant-pathogen interaction	9/1133	18/7206	0.000717915781603
ko04540	Gap junction	35/1133	128/7206	0.000797622662387
ko04924	Renin secretion	26/1133	86/7206	0.00081098781408
ko04964	Proximal tubule bicarbonate reclamation	12/1133	29/7206	0.000822996233984
ko04972	Pancreatic secretion	31/1133	111/7206	0.00089689788756
ko04915	Estrogen signaling pathway	35/1133	131/7206	0.00100281350655
ko04976	Bile secretion	24/1133	80/7206	0.00105094017087
ko00480	Glutathione metabolism	1/1133	55/7206	0.00134756074757
ko04014	Ras signaling pathway	64/1133	279/7206	0.00135441521858
ko05110	Vibrio cholerae infection	20/1133	63/7206	0.00135952050077
ko04141	Protein processing in endoplasmic reticulum	14/1133	184/7206	0.00136275661092
ko04923	Regulation of lipolysis in adipocytes	23/1133	77/7206	0.00145117977925
ko05410	Hypertrophic cardiomyopathy (HCM)	27/1133	100/7206	0.00338107842353
ko04510	Focal adhesion	22/1133	240/7206	0.0037322707918
ko04930	Type II diabetes mellitus	17/1133	54/7206	0.00385901702644
ko00240	Pyrimidine metabolism	7/1133	110/7206	0.00508349326906
ko04146	Peroxisome	5/1133	89/7206	0.00512901426348
ko04750	Inflammatory mediator regulation of TRP channels	31/1133	122/7206	0.00536757252288
ko04922	Glucagon signaling pathway	32/1133	128/7206	0.00653417633782
ko03420	Nucleotide excision repair	1/1133	46/7206	0.0069444192702
ko00562	Inositol phosphate metabolism	24/1133	89/7206	0.00751558407483
ko04630	Jak-STAT signaling pathway	10/1133	132/7206	0.00754293336898
ko05321	Inflammatory bowel disease (IBD)	2/1133	56/7206	0.00867849161079
ko04711	Circadian rhythm - fly	6/1133	13/7206	0.00945208394354
ko04115	p53 signaling pathway	4/1133	74/7206	0.00986441467055
ko03022	Basal transcription factors	1/1133	44/7206	0.0106698873454
ko05162	Measles	9/1133	120/7206	0.0108641584922
ko05016	Huntington's disease	21/1133	215/7206	0.0131878351285
ko04330	Notch signaling pathway	3/1133	62/7206	0.0134784774868
ko04622	RIG-I-like receptor signaling pathway	3/1133	62/7206	0.0134784774868
ko05131	Shigellosis	5/1133	82/7206	0.0137238765083
ko04214	Apoptosis - fly	4/1133	72/7206	0.0138317565861
ko04640	Hematopoietic cell lineage	3/1133	64/7206	0.0141334380097
ko00604	Glycosphingolipid biosynthesis - ganglio series	6/1133	14/7206	0.0143746358073
ko00980	Metabolism of xenobiotics by cytochrome P450	1/1133	40/7206	0.01524357765
ko05200	Pathways in cancer	59/1133	492/7206	0.0175419909322
ko00982	Drug metabolism - cytochrome P450	1/1133	37/7206	0.0226697073074
ko04657	IL-17 signaling pathway	6/1133	87/7206	0.0247876788423
ko05133	Pertussis	6/1133	87/7206	0.0247876788423
ko05145	Toxoplasmosis	11/1133	126/7206	0.0262772210713
ko05219	Bladder cancer	2/1133	48/7206	0.0264015221723
ko05217	Basal cell carcinoma	4/1133	68/7206	0.0275910630309
ko04973	Carbohydrate digestion and absorption	12/1133	42/7206	0.031274984017
ko03018	RNA degradation	6/1133	84/7206	0.0331695025299
ko04210	Apoptosis	18/1133	180/7206	0.0373019166886
ko05206	MicroRNAs in cancer	18/1133	177/7206	0.0461381951872
ko04658	Th1 and Th2 cell differentiation	8/1133	96/7206	0.0472866080709
ko04810	Regulation of actin cytoskeleton	30/1133	264/7206	0.0475168049707
ko05215	Prostate cancer	10/1133	111/7206	0.0488594679295